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Breast cancer classification algorithm to identify 20 gene signature developed using Microsoft Excel

Using readily available computer programs, researchers have developed a system to identify genes that will be useful in the classification of breast cancer. The algorithm, described in BioMed Central's open access Journal of Experimental & Clinical Cancer Research will enable researchers to quickly generate valuable gene signatures without specialized software or extensive bioinformatics training.

2 Sep 2010

Researchers develop new technique to trace counterfeit drugs

Counterfeiting of drugs is a huge industry with an annual turnover of more than SEK 500 billion. In Africa the situation is extremely serious. Half of the malaria medication sold there could be ineffective or even harmful. Researchers from Lund and the UK have now developed a technique that could resolve the situation.

2 Sep 2010

Researchers dispute study findings that show greater incidence of surgery for children with CD

A new multi-center study of 854 children with Crohn's disease shows a 5-year cumulative risk of bowel surgery is significantly lower than reported in recent studies. The findings of the study, led by Hasbro Children's Hospital, also indicate that children diagnosed between ages 13 and 16 had an increased risk of bowel surgery, and that a common treatment that begins at diagnosis, immunomodulator therapy, did not alter the risk of surgery.

2 Sep 2010

First Edition: September 2, 2010

Today's headlines include reports about a new study examining the impact of the health overhaul on the small business workforce.

2 Sep 2010

Agent Orange cases expanded; Added costs raise fiscal concerns

Hundreds of thousands of Vietnam War veterans are receiving disability compensation for diseases normally associated with aging - not combat - because of the possibility of a link Agent Orange exposure. The diseases in question range from diabetes, for which 270,000 veterans receive Agent Orange-related checks, to erectile dysfunction.

2 Sep 2010

First Phase I/II clinical trial to test MK-0752 in patients with advanced pancreatic cancer

Cancer Research UK's Drug Development Office has launched a clinical trial* to test an experimental drug in patients with advanced (Stage IV) pancreatic cancer - one of the most difficult cancers to treat.

2 Sep 2010

Cannabis Science issues statement on marijuana study for post-surgery neuropathic pain

Cannabis Science, Inc., a pioneering U.S. biotech company developing pharmaceutical cannabis products, has issued a statement regarding a Canadian study on marijuana and intractable post-traumatic or post-surgery neuropathic pain that did not respond to conventional treatment.

2 Sep 2010

Study links community violence with asthma hospitalizations, emergency department visits

Patients with asthma who are exposed to violence in their community are at an increased risk for an asthma-related hospitalization and emergency room visits for asthma or any cause, according to new research from the University Of Pennsylvania School of Medicine. Exposure to community violence has been linked to more symptoms in pediatric asthma patients; however the new research adds to this finding with a longitudinal study showing a connection in an adult population and more than symptoms - actual emergency department visits and hospitalizations.

2 Sep 2010

More patients research their own diseases, seek to manage chronic conditions

News outlets report on how the delivery of health care is being changed by empowered patients.

2 Sep 2010

Researcher awarded $1.8M grant to investigate sex differences in anxiety

Anxiety disorders afflict women twice as often as men, but estrogen might not be the reason. Testosterone, though, could be. That is one of the preliminary findings in the lab of Florida State University researcher Mohamed Kabbaj, associate professor in the College of Medicine. He recently was awarded a five-year, $1.8 million grant from the National Institute of Mental Health to investigate the sex differences in anxiety.

2 Sep 2010

HHS Secretary announces grants for patient-centered outcome research

HHS Secretary Kathleen Sebelius today announced three sets of grants and cooperative agreements totaling nearly $17 million for patient-centered outcomes research (PCOR), or research that compares treatments and strategies to improve health outcomes for patients.

2 Sep 2010

TGen researchers use RNAi-based screening to study Ewing's sarcoma

The first study of Ewing's sarcoma that screened hundreds of genes based on how they affect cell growth has identified two potential anti-cancer drug targets, according to a scientific paper by the Translational Genomics Research Institute published this month in the journal Molecular Cancer.

2 Sep 2010

Skills for Health publishes English regional briefings on skills and labour market environment

New resources to help health sector employers understand and respond to the fast-changing regional skills and labour market environment have been published by Skills for Health, the UK's Skills Council for healthcare.

2 Sep 2010

Study: Preemptive surgery may help prevent cancer for some women

A study published in the Journal of the American Medical Association suggests that women with a gene mutation linked to breast and ovarian cancer face lower risks of developing such cancer after receiving mastectomies or having their ovaries removed, The Wall Street Journal reports.

2 Sep 2010

HIV-infected children who receive HAART require revaccination: Researchers

HIV-infected children receiving highly active antiretroviral therapy may require revaccination to maintain immunity against preventable diseases. There remains no standard or official recommendation on revaccination of children receiving HAART, an effective intervention in reducing morbidity and mortality in HIV-infected children.

2 Sep 2010

Cellerant Therapeutics signs contract with BARDA to develop CLT-008 therapy for ARS

Cellerant Therapeutics Inc., a biotechnology company developing novel hematopoietic stem cell-based cellular and antibody therapies for blood disorders and cancer, announced today that it has signed a contract valued at up to $153 million over five years with the Biomedical Advanced Research and Development Authority (BARDA) in the Office of the Assistant Secretary for Preparedness and Response of the Department of Health and Human Services, to develop CLT-008, a cellular therapy for the treatment of Acute Radiation Syndrome (ARS).

2 Sep 2010

Promega to provide FuGENE HD Transfection Reagent throughout life science market

Promega Corporation announces it will provide FuGENE HD Transfection Reagent throughout the life science market. The comprehensive, direct use offering from Promega means any life scientist can utilize FuGENE technology with no licensing requirements. FuGENE HD enables the transfection of DNA into many cell types with high efficiency and little-to-no toxicity.

2 Sep 2010

WHO proposes creation of African Public Health Emergency Fund, strategy to reduce alcohol use in Africa

During the 60th session of the Africa Committee of the WHO on Monday, Luis Sambo, regional director of the WHO for Africa, proposed the creation of a public health emergency fund to provide financial support to African countries in emergency situations, Agencia AngolaPress reports (8/30).

2 Sep 2010

ThromboGenics second microplasmin Phase III trial for non-surgical treatment of VMA meets primary endpoint

ThromboGenics NV, a biopharmaceutical company focused on the discovery and development of innovative treatments for eye disease, vascular disease and cancer announces that its second Phase III trial evaluating microplasmin for the non-surgical treatment of vitreomacular adhesion (VMA) has met its primary endpoint.

2 Sep 2010

Pfizer enters agreement to acquire FoldRx Pharmaceuticals

Pfizer Inc. and FoldRx Pharmaceuticals, Inc., a privately held drug discovery and clinical development company, today announced that they have entered into an agreement under which Pfizer will acquire FoldRx.

2 Sep 2010

Research News and Research

Breast cancer classification algorithm to identify 20 gene signature developed using Microsoft Excel

Researchers develop new technique to trace counterfeit drugs

Researchers dispute study findings that show greater incidence of surgery for children with CD

First Edition: September 2, 2010

Agent Orange cases expanded; Added costs raise fiscal concerns

First Phase I/II clinical trial to test MK-0752 in patients with advanced pancreatic cancer

Cannabis Science issues statement on marijuana study for post-surgery neuropathic pain

Study links community violence with asthma hospitalizations, emergency department visits

More patients research their own diseases, seek to manage chronic conditions

Researcher awarded $1.8M grant to investigate sex differences in anxiety

HHS Secretary announces grants for patient-centered outcome research

TGen researchers use RNAi-based screening to study Ewing's sarcoma

Skills for Health publishes English regional briefings on skills and labour market environment

Study: Preemptive surgery may help prevent cancer for some women

HIV-infected children who receive HAART require revaccination: Researchers

Cellerant Therapeutics signs contract with BARDA to develop CLT-008 therapy for ARS

Promega to provide FuGENE HD Transfection Reagent throughout life science market

WHO proposes creation of African Public Health Emergency Fund, strategy to reduce alcohol use in Africa

ThromboGenics second microplasmin Phase III trial for non-surgical treatment of VMA meets primary endpoint

Pfizer enters agreement to acquire FoldRx Pharmaceuticals

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