Laboratory News and Research

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VIB research reveals new insights into ALS

Research into amyotrophic lateral sclerosis (ALS) conducted by VIB-KU Leuven has led to interesting and unexpected conclusions.

14 Jul 2016

Study finds evidence that PD-1 antibody may benefit men with metastatic prostate cancer

Restoring tumor-specific immunity is a treatment strategy that works well in melanoma and lung cancer patients. Now a new study out of the OHSU Knight Cancer Institute is reviving hope that the approach also may help men with life-threatening prostate cancer.

14 Jul 2016

Losing weight can lower levels of some proteins linked to tumor growth

Overweight and obese women who lost weight through diet and exercise lowered the levels of certain proteins in their blood that play a role in angiogenesis, the process of blood vessel growth that can promote the growth and survival of cancer cells

14 Jul 2016

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

The Wistar Institute is pleased to announce that the National Institutes of Health has awarded a nearly $23 million Martin Delaney Collaboratories for HIV Cure Research grant to the BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy, a consortium of top HIV researchers led by co-principal investigators Luis J. Montaner, D.V.M., D.Phil., director of the HIV-1 Immunopathogenesis Laboratory at The Wistar Institute Vaccine Center, and James L. Riley, Ph.D., research associate professor at the Perelman School of Medicine at the University of Pennsylvania.

13 Jul 2016

Regular drug use may hamper moral decision making

Regular cocaine and methamphetamine users can have difficulty choosing between right and wrong, perhaps because the specific parts of their brains used for moral processing and evaluating emotions are damaged by their prolonged drug habits.

13 Jul 2016

New diagnostic model may become cheaper and easier alternative to screen for NAFLD

Researchers have developed a diagnostic model that is highly predictive of nonalcoholic fatty liver disease (NAFLD).

13 Jul 2016

Scientists discover new, unexpected features of collagen

Scientists at the National Institutes of Health are reporting new, unexpected details about the fundamental structure of collagen, the most abundant protein in the human body.

13 Jul 2016

Antibodies from survivors of filovirus infection may offer protection against other filoviral diseases

Ebola and Marburg filovirus disease outbreaks have typically occurred as isolated events, confined to central Africa.

13 Jul 2016

Two new studies find potential genetic cause and new treatment method for autoimmune diseases

The American Autoimmune Related Diseases Association, Inc. is spotlighting two new research studies originally reported in ScienceDaily.

13 Jul 2016

Changes in cavefish metabolism could lead to new insights into diabetes

Cavefish that live in dark caves with only sporadic access to food show symptoms similar to diabetes, but don't appear to experience any health problems.

13 Jul 2016

Impact of diet may depend on individual’s genetic composition

If you've ever seen a friend have good results from a diet but then not been able to match those results yourself, you may not be surprised by new findings in mice that show that diet response is highly individualized.

13 Jul 2016

Researchers study how skin stem cells respond to forces

All cells share the same genetic code, no matter if they are skin or brain cells. However, these cells are exposed to very different types of mechanical environments and mechanical stresses.

13 Jul 2016

Scientists identify timing of major metabolic shift in developing neurons

Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a source of energy.

13 Jul 2016

New ultra-fast approach to modeling protein interactions may pave way for drug development

Protein-protein interactions (PPIs) are the basis of cellular functions, and when these processes are compromised diseases such as cancer emerge. For years scientists have tried with mixed success to map out PPIs to understand cellular processes.

13 Jul 2016

Italian researchers identify new variant of emerging antibiotic resistance mechanism

A team of Italian investigators has discovered a new variant of an emerging antibiotic resistance mechanism. The new variant, dubbed mcr-1.2, confers resistance to colistin, a last-resort antibiotic against multidrug-resistant Gram-negative pathogens.

13 Jul 2016

Study shows workplace conditions may contribute to gender-based job stress

Social scientists have long known that women working in numerically male-dominated occupations like physics and firefighting report experiencing workplace stress, but men who work in numerically female-dominated occupations like nursing and child care do not.

13 Jul 2016

New multicomponent reactions to develop active compounds against sleeping sickness

Multicomponent reactions are protocols that ease the chemical synthesis of new compounds, and are particularly important to gain molecules with biological activity as therapeutic agents against several pathogens.

13 Jul 2016

Low levels of blood selenium may increase risk of liver cancer

A new study, published in current issue of The American Journal of Clinical Nutrition, shows that the highest levels of blood selenium or of selenoprotein P, the protein that distributes selenium from the liver around the body, are associated with a decreased risk of developing liver cancer (particularly hepatocellular carcinoma), even when all other major liver cancer risk factors are taken into account.

13 Jul 2016

Machine learning can improve autism screening and diagnostics

Approximately one in 68 people are on the autism spectrum. Experts are unanimous on this: early intervention is critical for improving communication skills and addressing behavioral issues.

12 Jul 2016

Phase III clinical study of promising prostate cancer drug reveals surprising results

A recently published international clinical Phase III trial of a promising drug for treating advanced prostate cancer ended with surprising results: the new therapeutic agent failed to achieve any significant improvement in the overall survival of patients compared with the established standard treatment.

12 Jul 2016

Laboratory News and Research

VIB research reveals new insights into ALS

Study finds evidence that PD-1 antibody may benefit men with metastatic prostate cancer

Losing weight can lower levels of some proteins linked to tumor growth

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

Regular drug use may hamper moral decision making

New diagnostic model may become cheaper and easier alternative to screen for NAFLD

Scientists discover new, unexpected features of collagen

Antibodies from survivors of filovirus infection may offer protection against other filoviral diseases

Two new studies find potential genetic cause and new treatment method for autoimmune diseases

Changes in cavefish metabolism could lead to new insights into diabetes

Impact of diet may depend on individual’s genetic composition

Researchers study how skin stem cells respond to forces

Scientists identify timing of major metabolic shift in developing neurons

New ultra-fast approach to modeling protein interactions may pave way for drug development

Italian researchers identify new variant of emerging antibiotic resistance mechanism

Study shows workplace conditions may contribute to gender-based job stress

New multicomponent reactions to develop active compounds against sleeping sickness

Low levels of blood selenium may increase risk of liver cancer

Machine learning can improve autism screening and diagnostics

Phase III clinical study of promising prostate cancer drug reveals surprising results

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