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WRAIR collaborates with Sanofi Pasteur to develop ZPIV vaccine candidate

The Walter Reed Army Institute of Research announces a Cooperative Research and Development Agreement for the development of a Zika vaccine candidate with Sanofi Pasteur, the vaccines division of Sanofi.

7 Jul 2016

AMPK protein activated during fasting regulates hunger neurons in the brain

Neurons in the brain that control hunger are regulated by AMPK, a protein activated during fasting, report researchers from Tufts University School of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School in Neuron on July 6, 2016.

6 Jul 2016

New risk calculator can assess individual's risk of developing psychosis

A new risk calculator can predict an individual's risk of developing psychotic disorders such as schizophrenia, according to a new study published today in The American Journal of Psychiatry.

6 Jul 2016

Researchers identify potential biomarker for Parkinson's disease in biobanked urine samples

For more than five years, urine and cerebral-spinal fluid samples from patients with Parkinson's disease have been locked in freezers in the NINDS National Repository, stored with the expectation they might someday help unravel the still-hidden course of this slow-acting neurodegenerative disease.

6 Jul 2016

Penn researchers develop low-cost genetic test for Zika virus

University of Pennsylvania engineers have developed a rapid, low-cost genetic test for the Zika virus.

6 Jul 2016

CDC invests in Donator’s unique heat stabilization technology

Denator, the Swedish-based biotechnology company specialized in biological sample preparation technologies announced today that the Center for Disease Control and Prevention, Atlanta, had made a major purchase of its proprietary heat stabilization technology Stabilizor T1™.

6 Jul 2016

miRNAs may improve risk prediction in CAD

Single microRNAs derived from peripheral blood predict cardiovascular mortality in patients with coronary artery disease, German research shows.

6 Jul 2016

Researchers demonstrate simple approach to prove how classes of new drugs work

A collaborative effort by cancer researchers at Cold Spring Harbor Laboratory and chemists at Boehringer Ingelheim, a pharmaceutical firm, has resulted in the identification of a new drug target in leukemia and creation of a candidate drug that hits the target.

6 Jul 2016

Replacing saturated fats with unsaturated fats in diet can confer substantial health benefits

Consuming higher amounts of unsaturated fats was associated with lower mortality, according to a study from Harvard T.H. Chan School of Public Health.

5 Jul 2016

Celltrion Healthcare commits to develop lab tests for evidence-based decision-making in anti-TNF treatment

Celltrion Healthcare, a global biopharmaceutical company, today announced its research commitment to develop laboratory tests that will determine both drug and anti-drug antibody levels in the blood, enabling physicians to identify when patients on an anti-tumour necrosis factor drug require a change of dose or a switch to a different treatment in the class.

5 Jul 2016

Study shows how pasta consumption is linked to reduced likelihood of general, abdominal obesity

In recent years pasta gained a bad reputation: it will fatten you. This led lots of people to limit its consumption, often as part of some aggressive "do it yourself" diets. Now a study conducted by the Department of Epidemiology, I.R.C.C.S. Neuromed in Pozzilli, Italy, does justice to this fundamental element of the Mediterranean diet, showing how pasta consumption is actually associated with a reduced likelihood of both general and abdominal obesity.

4 Jul 2016

Novel technique could help discover genes linked to complex traits in any animal model

Mice are one of the most commonly used laboratory organisms, widely used to study everything from autism to infectious diseases. Yet genomic studies in mice have lagged behind those in humans.

4 Jul 2016

Neuroscientists map neural connections over long distances in the brain

A team of neuroscientists at the Champalimaud Centre for the Unknown, in Lisbon, has been able to map single neural connections over long distances in the brain.

4 Jul 2016

Immunotherapy in conjunction with drugs could be effective in treating pancreatic cancer

While immune therapy has proven effective in treating certain types of cancer, especially lung cancer and melanoma, tumors of the pancreas remain among the most difficult to treat and, so far, are impervious to immune-based therapies.

4 Jul 2016

Study shows how genetic variants control immune cell response to pathogens

A study that is first in its kind and published in Nature Medicine today has looked at how far genetic factors control the immune cell response to pathogens in healthy individuals.

4 Jul 2016

Study provides insight into why individual mycobacteria respond differently to antibiotics

Tuberculosis is one of the most common infectious diseases in the world, infecting almost 10 million people each year. Treating the disease can be challenging and requires a combination of multiple antibiotics delivered over several months.

4 Jul 2016

Studies shed more light on relation between bacteria, immune system and antibiotics

Antibiotics and the immune system are the two forces that cope with bacterial infections. Now, two studies from Isabel Gordo's laboratory, at Instituto Gulbenkian de Ciência, show for the first time that resistance to antibiotics and to the immune system is interconnected in bacteria.

4 Jul 2016

New test strip can rapidly, cost-effectively detect disease pathogens

At present, bacteria, fungi or viruses can generally only be detected with certainty by way of elaborate laboratory tests or animal experiments. The food and pharmaceutical industries would like to have faster tests to check their products.

4 Jul 2016

Traumatic images induce stronger alcohol craving than stress in military veterans

Post-traumatic stress disorder and alcohol dependence (AD) are two of the most common and debilitating disorders diagnosed among American military veterans. AD and PTSD often occur together, and this co-occurrence has a worse prognosis than either disorder alone.

4 Jul 2016

New strategy treats fatal autoimmune disease without outward off-target effects

In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists from the Perelman School of Medicine at the University of Pennsylvania have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system.

4 Jul 2016

Laboratory News and Research

WRAIR collaborates with Sanofi Pasteur to develop ZPIV vaccine candidate

AMPK protein activated during fasting regulates hunger neurons in the brain

New risk calculator can assess individual's risk of developing psychosis

Researchers identify potential biomarker for Parkinson's disease in biobanked urine samples

Penn researchers develop low-cost genetic test for Zika virus

CDC invests in Donator’s unique heat stabilization technology

miRNAs may improve risk prediction in CAD

Researchers demonstrate simple approach to prove how classes of new drugs work

Replacing saturated fats with unsaturated fats in diet can confer substantial health benefits

Celltrion Healthcare commits to develop lab tests for evidence-based decision-making in anti-TNF treatment

Study shows how pasta consumption is linked to reduced likelihood of general, abdominal obesity

Novel technique could help discover genes linked to complex traits in any animal model

Neuroscientists map neural connections over long distances in the brain

Immunotherapy in conjunction with drugs could be effective in treating pancreatic cancer

Study shows how genetic variants control immune cell response to pathogens

Study provides insight into why individual mycobacteria respond differently to antibiotics

Studies shed more light on relation between bacteria, immune system and antibiotics

New test strip can rapidly, cost-effectively detect disease pathogens

Traumatic images induce stronger alcohol craving than stress in military veterans

New strategy treats fatal autoimmune disease without outward off-target effects

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