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Merlin protein controls adult cell activity to cause liver cancer

A protein known to be involved in a rare hereditary cancer syndrome may have a role in the regulation of liver stem cells and the development of liver cancer. In the August 15 issue of Genes & Development, a Massachusetts General Hospital (MGH) research team describes finding that the protein called merlin, encoded by the NF2 (neurofibromatosis type 2) gene, controls the activity of adult stem cells that give rise to the two major types of liver cells.

13 Aug 2010

Insurers, small businesses and ER care all affected by overhaul

News outlets consider the impact of health reform on insurers — who are seeking flexibility on mandates — as well as changes to premiums, small businesses and emergency room care.

13 Aug 2010

Research identifies intracellular mechanism for altering blood vessels permeability for tumours treatment

Dr. Jean-Philippe Gratton, Director of the Endothelial cell biology research unit at the Institut de recherches cliniques de Montr-al (IRCM), identifies a new intracellular mechanism responsible for modulating vascular permeability: the nitrosylation of beta-catenin protein by nitric oxide. This scientific breakthrough could have a possible impact on the treatment of cancerous tumours by altering the permeability of the blood vessels irrigating them. Dr. Gratton's team will publish the results of its research tomorrow in the scientific journal Molecular Cell.

13 Aug 2010

Single neurons in brain distinguish different temporal sequences of incoming information

Single neurons in the brain are surprisingly good at distinguishing different sequences of incoming information according to new research by UCL neuroscientists.The study, published today in Science and carried out by researchers based at the Wolfson Institute for Biomedical Research at UCL, shows that single neurons, and indeed even single dendrites, the tiny receiving elements of neurons, can very effectively distinguish between different temporal sequences of incoming information.

13 Aug 2010

Emergent BioSolutions enters agreement to acquire Trubion Pharmaceuticals

Emergent BioSolutions Inc. announced today it has entered into a definitive agreement to acquire Trubion Pharmaceuticals, Inc. for upfront consideration of $96.8 million of value and up to $38.7 million of success-based milestones, resulting in a total consideration of up to $135.5 million. The acquisition will diversify Emergent's product development pipeline with the addition of Trubion's two clinical-stage product candidates focused on the targeted disease areas of oncology and autoimmunity.

13 Aug 2010

American Society of Hematology offers recommendations to propel collaborative research in regenerative medicine

The American Society of Hematology has developed specific recommendations to the scientific community and federal agencies to help propel collaborative research in regenerative medicine in order to make real strides in improving patient care. These recommendations were released today in Blood, ASH's premier scientific journal, in the article titled "Enhancing Research in Regenerative Medicine."

13 Aug 2010

Polls show public confusion continues regarding new health law

In three recent polls, large percentages of Americans said the health law would cut Medicare benefits, slash doctors pay and ration health care to patients, all false claims that remain pervasive despite reform supporters' efforts to educate the public, USA Today reports. "Six weeks before the nation's health care delivery system begins a huge transformation, confusion reigns.

13 Aug 2010

OriGene Technologies announces acquisition of Blue Heron Biotechnology

OriGene Technologies, Inc., a gene-centric life sciences company, announces the acquisition of Blue Heron Biotechnology, a pioneer in the gene synthesis business since 1999.

13 Aug 2010

Arrowhead third-quarter 2010 net loss decreases to $0.4 million

Arrowhead Research Corporation today announced financial results for its fiscal 2010 third quarter ended June 30, 2010.

13 Aug 2010

FTC works to crack down on health care 'discount' plans

Reuters: "The Federal Trade Commission said on Wednesday it is working with 24 states to crack down on sellers of medical discount plans that market them as health insurance that covers doctors, hospitals and other services." The prevalence of such plans has increased since March, when Congress passed its health overhaul.

13 Aug 2010

Today's Opinions: Health law's effect for Democrats; Canadians' view; Cutting Medicare costs; The health issue in Tenn. Governor's race

Despite lofty predictions that a broad-based Democratic constituency would be activated by the health care reform bill, recent polling shows that the bill has been a disaster for the party — with near 60 percent of voters saying that they oppose the measure (Douglas Schoen, 8/11).

13 Aug 2010

Research finds genetic roots of alcoholism in humans

A novel mutation found in a mouse gene might provide new insights into the genetic roots of alcoholism in humans, according to a study led by researchers at the Ernest Gallo Clinic and Research Center and the University of California, San Francisco. The study is published August 12th in the open-access journal PLoS Genetics.

13 Aug 2010

New research with agitated monkeys may help predict childhood anxiety & depression

According to the latest discovery from the University of Wisconsin-Madison School of Medicine and Public Health, there may be a possible link between brain activity and childhood anxiety.

12 Aug 2010

Heater replacement funding falters

Education Minister Verity Firth promised parents two weeks ago that 55,000 unflued gas heaters in the state's schools that could result in respiratory problems for children would be replaced. However the Government was unable to find $400 million for the project and parents and students need to wait before the heaters are actually replaced. The plan is now to take up a 10-year replacement program.

12 Aug 2010

Aeterna Zentaris second-quarter revenues decrease to $5.6 million

Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrinology, today reported financial and operating results for the second quarter ended June 30, 2010.

12 Aug 2010

Interleukin Genetics, University of Michigan to conduct landmark clinical study on periodontal disease

Interleukin Genetics, Inc. announced today that the Company has signed an agreement with the University of Michigan to conduct a landmark clinical study on risk factors predictive of periodontal disease progression to tooth loss using a new version of Interleukin Genetics' PST genetic test.

12 Aug 2010

Gentium second-quarter total revenues increase to EUR 7.55 million

Gentium S.p.A. today reported financial results for the first half of 2010 and for the quarter ended June 30, 2010. The Company reports its financial condition and operating results using U.S. Generally Accepted Accounting Principles (GAAP). The Company's financial statements are prepared using the Euro as its functional currency.

12 Aug 2010