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Labopharm launches antidepressant OLEPTRO for major depressive disorder in U.S.

Labopharm Inc. today announced that OLEPTRO(TM) (trazodone hydrochloride extended-release tablets), a novel once-daily formulation of the antidepressant trazodone, has been launched in the United States by its joint venture with Gruppo Angelini, Angelini Labopharm. OLEPTRO(TM) is indicated for the treatment of major depressive disorder (MDD) in adults. The efficacy of OLEPTRO(TM) has been established in a trial of outpatients with MDD as well as in trials with the immediate release formulation of trazodone.

11 Aug 2010

Progestins have tumor-stage specific effects that determine promotion, suppression: Study

Progestins are used in hormone replacement therapies to counteract the negative effects of estrogen on the uterus and reduce the risk of uterine cancer. However, evidence in recent studies and clinical trials has demonstrated that progestins increase the risk of breast cancer. Now, University of Missouri researchers have compared four types of progestins used in hormone replacement therapies and found significantly different outcomes on the progression of breast cancer in an animal model depending on the type of progestins used.

11 Aug 2010

Cardiovascular Systems fourth-quarter revenue increases 15% to $18.0 million

Cardiovascular Systems, Inc., a medical device company developing and commercializing innovative interventional treatment systems for vascular disease, today reported financial results for its fiscal fourth quarter and year ended June 30, 2010.

11 Aug 2010

Scientists develop new method to enable drug release inside cancer cells

Scientists from UCLA's California NanoSystems Institute and Korea's Yonsei University have developed an innovative method that enables nanomachines to release drugs inside living cancer cells when activated remotely by an oscillating magnetic field.The new system - the first to utilize a class of porous nanomaterials driven by a magnetic core - has the potential to improve both targeted drug-delivery and magnetic resonance imaging in the treatment of cancer and other diseases.

11 Aug 2010

State News: Ex-Anthem Blue Cross president speaks out; Clinics to fill in N.M. primary care gap

The Los Angeles Times: "The abrupt resignation last month of Anthem Blue Cross' president is offering a glimpse of an internal struggle that has roiled California's largest for-profit health insurer for months. Leslie Margolin was the public face of Anthem this year when it sought to raise individual insurance rates as much as 39%.

11 Aug 2010

Study suggests zinc supplementation may reduce pneumonia risk

A high proportion of nursing facility residents were found to have low serum (blood) zinc concentrations during an observational study funded by the Agricultural Research Service (ARS) and the National Institute of Aging. The scientists found that those with normal blood zinc concentrations were about 50 percent less likely to develop pneumonia than those with low concentrations.

11 Aug 2010

ACT signs agreement to select novel clinical candidates for two cancer metabolic programs

Advanced Cancer Therapeutics (ACT), a privately held company dedicated to bringing new anti-cancer therapies to market, today announced that it has signed an exclusive agreement to leverage the translational research expertise of Dr. Jason Chesney, Associate Professor, Department of Medicine at the University of Louisville's James Graham Brown Cancer Center (Brown Cancer Center), to identify new clinical candidates for the prevention and treatment of cancers against two key cancer metabolic targets.

11 Aug 2010

Study reveals no evidence of link between bisphosphonates to esophageal cancer risk

Although some reports have suggested a link between the use of oral bisphosphonates (drugs that prevent the loss of bone mass) and esophageal cancer, analysis of medical data from more than 80,000 patients in the United Kingdom found that use of these drugs was not significantly associated with new cases of esophageal or gastric cancer, according to a study in the August 11 issue of JAMA.

11 Aug 2010

Opinions: HIV prevention research; Foreign aid; Sanitation; Aid, self-reliance

"Microbicides, vaccines and other new approaches will one day join proven HIV-prevention strategies, including condoms, male circumcision and clean needles. How soon that day comes will depend on whether funders and the scientific community can develop the more collaborative approaches to HIV prevention research needed to address this fast-moving epidemic," Global HIV Vaccine Enterprise leaders Alan Bernstein, executive director, and Peter Piot, chair, write in a Globe and Mail opinion piece.

11 Aug 2010

Today's Opinions and Editorials: Bringing down health care costs; More on the Medicare trustees report

Short of transforming the medical payment system, can we bring down health care costs by feasible fixes? Yes, by reducing the number of services that must be covered by every insurance policy and requiring higher copayments for patients using the highest cost providers (Robert Pozen, 8/10).

11 Aug 2010

Telephone monitoring can save heart failure patients: Study

Chronic heart failure needs constant care and regular monitoring. Now research says remote monitoring, either over the phone or using wireless technology, helps people with heart failure live longer and stay out of hospital.

10 Aug 2010

Breath test to detect cancer: Study

According to researchers cancer may soon be detectable using a breath test. They are now developing sensors that can detect chemical markers of lung, breast, bowel and prostate cancer in a person's breath. The new portable device has been purported as an “electronic nose” that can detect early cancers. As a cancer grows, the surface of the cells emits chemicals. The research found that sensors – involving gold nanoparticles – could be used to detect these chemicals in the breath.

10 Aug 2010

Study results provide rationale for use of PI3K inhibitors in therapeutic settings

Research at the Babraham Institute, investigating how white blood cells known as B cells develop, has revealed that genes from the Phosphatidylinositol 3-kinase family of enzymes are critical in enabling the B cells to produce antibodies in the spleen and lymph nodes.

10 Aug 2010

Arrowhead Research signs option agreement for new technology platform to kill fat tissue

Arrowhead Research Corporation today announced that it has signed an option agreement with The University of Texas MD Anderson Cancer Center to negotiate a license in a defined field to a class of compounds that is believed to kill fat tissue by specifically targeting the blood vessels that supply it. The technology was developed in the laboratory of Drs. Renata Pasqualini and Wadih Arap at MD Anderson in Houston, Texas.

10 Aug 2010

Quick-Med develops new NIMBUS Advanced Active prototype wound dressing

Quick-Med Technologies, Inc. announced today the development of a new prototype wound dressing, NIMBUS® Advanced Active, developed as part of ongoing research currently being funded by the U.S. Army Medical Research and Material Command under a $900,000 Small Business Innovation Research (SBIR) grant. NIMBUS was competitively selected by the U.S. Army for evaluation in the healing of vesicant injuries, and this new dressing is the first "active" wound healing product developed by Quick-Med.

10 Aug 2010

Inhibitex reports net loss of $5.6 million for second-quarter 2010

Inhibitex, Inc. today announced its financial results for the second quarter ended June 30, 2010.

10 Aug 2010

Analysis finds no evidence that inclusion of retinyl palmitate in sunscreens can cause cancer

Despite previous concerns about the cancer-causing potential of sunscreens containing retinyl palmitate (vitamin A), an independent analysis published online in the Journal of the American Academy of Dermatology determined that there is no evidence that the inclusion of retinyl palmitate in sunscreens can cause cancer in humans.

10 Aug 2010

Response Biomedical second-quarter revenue from product sales increases 2%

Response Biomedical Corporation today announced financial results for the second quarter and six months ended June 30, 2010.

10 Aug 2010

FDA grants Orphan Drug Designation to YM BioSciences' JAK1/2 inhibitor

YM BioSciences Inc., announced that the Office of Orphan Products Development of the U.S. Food and Drug Administration has granted Orphan Drug Designation to the Company's highly-selective JAK1/2 inhibitor, CYT387, for the treatment of myelofibrosis, a chronic debilitating unmet medical need, in which a patient's bone marrow is replaced by scar tissue, and for which treatment options are limited or unsatisfactory.

10 Aug 2010

First Edition: August 10, 2010

In today's news, the House is back in town... though just for a day. Lawmakers will consider a state aid package that includes $16 billion in federal Medicaid assistance.

10 Aug 2010

Research News and Research

Labopharm launches antidepressant OLEPTRO for major depressive disorder in U.S.

Progestins have tumor-stage specific effects that determine promotion, suppression: Study

Cardiovascular Systems fourth-quarter revenue increases 15% to $18.0 million

Scientists develop new method to enable drug release inside cancer cells

State News: Ex-Anthem Blue Cross president speaks out; Clinics to fill in N.M. primary care gap

Study suggests zinc supplementation may reduce pneumonia risk

ACT signs agreement to select novel clinical candidates for two cancer metabolic programs

Study reveals no evidence of link between bisphosphonates to esophageal cancer risk

Opinions: HIV prevention research; Foreign aid; Sanitation; Aid, self-reliance

Today's Opinions and Editorials: Bringing down health care costs; More on the Medicare trustees report

Telephone monitoring can save heart failure patients: Study

Breath test to detect cancer: Study

Study results provide rationale for use of PI3K inhibitors in therapeutic settings

Arrowhead Research signs option agreement for new technology platform to kill fat tissue

Quick-Med develops new NIMBUS Advanced Active prototype wound dressing

Inhibitex reports net loss of $5.6 million for second-quarter 2010

Analysis finds no evidence that inclusion of retinyl palmitate in sunscreens can cause cancer

Response Biomedical second-quarter revenue from product sales increases 2%

FDA grants Orphan Drug Designation to YM BioSciences' JAK1/2 inhibitor

First Edition: August 10, 2010

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