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Doctor survived Cambodia’s killing fields, but not Covid

Linath Lim's life was shaped by starvation. She was not yet 13 when the Khmer Rouge seized power in Cambodia and ripped her family apart. The totalitarian regime sent her and four siblings to work camps, where they planted rice and dug irrigation canals from sunrise to sunset — each surviving on two ladles of rice gruel a day. One disappeared, never to be found.

7 Apr 2021

Study: Disparities persist in prescribing comfort care for ischemic stroke patients

Receiving palliative or hospice care services was found to improve quality of life for hospitalized ischemic stroke patients, however, disparities persist in which patients are prescribed or have access to these holistic comfort care options, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

7 Apr 2021

Study indicates an amyloid link between melanoma and Parkinson’s disease

On the surface, Parkinson's disease - a neurodegenerative disorder - and melanoma - a type of skin cancer - do not appear to have much in common.

7 Apr 2021

UNION therapeutics’ COVID-19 candidates show promising results in phase 1 study

UNION therapeutics A/S (UNION) announced today that the results of a phase 1 study of inhaled and intranasal niclosamide (UNI911) have been published by The Lancet Regional Health – Europe.

7 Apr 2021

Gut microbiome communicates with horse’s cells to enhance their athletic performance

A horse’s gut microbiome communicates with its host by sending chemical signals to its cells, which has the effect of helping the horse to extend its energy output, finds a new study published in Frontiers in Molecular Biosciences.

7 Apr 2021

Study reveals sex-differences in aging of the brain stem cell niche

Ageing and age-related brain disease do not affect women and men in the same way. The adult brain constantly generates new brain cells called neurons from stem cells, a process called neurogenesis.

7 Apr 2021

New research could rescue failed immunotherapies for treating solid tumors

New research from the UVA Cancer Center could rescue once-promising immunotherapies for treating solid cancer tumors, such as ovarian, colon and triple-negative breast cancer, that ultimately failed in human clinical trials.

7 Apr 2021

Neurotechnology combined with saliva testing improves accuracy in measuring psychoactive effects of cannabis

A new study, released today in the scientific journal Advances in Therapy is providing critical evidence that neurotechnology combined with saliva testing can drastically reduce the likelihood of falsely determining cannabis impairment due to THC residual detection.

7 Apr 2021

Intermittent auscultation outperforms more modern methods at reducing cesarean sections

Intermittent auscultation, in which the baby’s heartbeat is monitored using a sonic aid or Doppler probe, outperforms more modern methods at reducing the number of emergency caesarean sections in labour, according to a new study led by researchers from the University of Warwick.

7 Apr 2021

Individuals with Major Depressive Disorder have accelerated cellular aging

Cells from individuals with Major Depressive Disorder (MDD) were found to have higher than expected rates of methylation at specific sites on their DNA, when compared to cells from healthy individuals without MDD, according to a study by a multidisciplinary team of UC San Francisco scientists, in collaboration with others.

7 Apr 2021

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Curing cancer has been the dream of countless doctors and researchers over the decades. Yet some types of cancer, whether because they affect relatively few people or lack influential advocates, receive less attention and funding than others.

7 Apr 2021

Study shows stronger link between Down syndrome and acute myeloid leukemia

A new large-scale study led by UC Davis Health and UC San Francisco researchers assessed the risks of leukemia in children with Down syndrome.

7 Apr 2021

High-intensity walking exercise benefits people with peripheral artery disease

No pain means no gain when it comes to reaping exercise benefits for people with peripheral artery disease (PAD), reports a new Northwestern Medicine study.

6 Apr 2021

New biomarker of glucocorticoid action could help clinicians to tailor treatments

Researchers have uncovered pathways involved in the body's response to glucocorticoid treatments and identified a novel biomarker that could be used to monitor how these drugs work in patients, according to a clinical study published today in eLife.

6 Apr 2021

UCI receives $4.2 million grant to study sporadic inclusion body myositis affecting aging adults

The National Institute of Arthritis and Musculoskeletal and Skin Diseases has awarded UCI a 5-year, $4.2 million grant to study sporadic inclusion body myositis (sIBM), which affects aging adults causing asymmetric muscle weakness and severe disability. The disease is currently untreatable and poorly understood.

6 Apr 2021

Researchers evaluate new drug for spinal muscular atrophy in a broader spectrum of patients

The rarity of spinal muscular atrophy (SMA) means that promising new treatments may be tested in only a limited spectrum of patients before approval. Investigators evaluated a newly approved drug, onasemnogene abeparvovec, in a broader spectrum of patients in order to obtain expanded data on its side effects profile.

6 Apr 2021

World's first human tracheal transplant performed by Mount Sinai surgeons

A team of Mount Sinai surgeons has performed the world's first human tracheal transplant--an achievement that has the potential to save the lives of thousands of patients around the world who have tracheal birth defects, untreatable airway diseases, burns, tumors, or severe tracheal damage from intubation, including those who had been hospitalized with COVID-19 and placed on a ventilator.

6 Apr 2021

FDA authorizes use of Symbiotica COVID-19 Self-Collected Antibody Test System

The U.S. Food and Drug Administration today announced it has issued an emergency use authorization for the Symbiotica COVID-19 Self-Collected Antibody Test System, the first antibody test authorized for use with home collected dried blood spot samples.

6 Apr 2021

Implantable sensor based on gold nanoparticles revolutionizes medical diagnostics

The idea of implantable sensors that continuously transmit information on vital values and concentrations of substances or drugs in the body has fascinated physicians and scientists for a long time. Such sensors enable the constant monitoring of disease progression and therapeutic success.

6 Apr 2021

Is non-severe SARS-CoV-2 infection characterized by early T cell proliferation?

To date, little evidence has been documented regarding the immune responses after the onset of the symptoms or virus detection. Further, no cross-sectional studies have been conducted that define the time of infection. Thereby, no report is available that explains the relationship between the earliest immune responses to COVID-19 and temporal kinetics. New research deals with this research gap using blood transcriptomics, multiparameter flow cytometry, and T cell receptor (TCR) sequencing methods.

6 Apr 2021

Blood News and Research

Doctor survived Cambodia’s killing fields, but not Covid

Study: Disparities persist in prescribing comfort care for ischemic stroke patients

Study indicates an amyloid link between melanoma and Parkinson’s disease

UNION therapeutics’ COVID-19 candidates show promising results in phase 1 study

Gut microbiome communicates with horse’s cells to enhance their athletic performance

Study reveals sex-differences in aging of the brain stem cell niche

New research could rescue failed immunotherapies for treating solid tumors

Neurotechnology combined with saliva testing improves accuracy in measuring psychoactive effects of cannabis

Intermittent auscultation outperforms more modern methods at reducing cesarean sections

Individuals with Major Depressive Disorder have accelerated cellular aging

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Study shows stronger link between Down syndrome and acute myeloid leukemia

High-intensity walking exercise benefits people with peripheral artery disease

New biomarker of glucocorticoid action could help clinicians to tailor treatments

UCI receives $4.2 million grant to study sporadic inclusion body myositis affecting aging adults

Researchers evaluate new drug for spinal muscular atrophy in a broader spectrum of patients

World's first human tracheal transplant performed by Mount Sinai surgeons

FDA authorizes use of Symbiotica COVID-19 Self-Collected Antibody Test System

Implantable sensor based on gold nanoparticles revolutionizes medical diagnostics

Is non-severe SARS-CoV-2 infection characterized by early T cell proliferation?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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