Research News and Research

RSS

GSK awards NCCN $4 million grant for study of ofatumumab and pazopanib

The National Comprehensive Cancer Network has been awarded two individual $2 million grants from GlaxoSmithKline to support clinical studies of ofatumumab (Arzerra®, GlaxoSmithKline) in the treatment of hematologic malignancies and pazopanib (Votrient®, GlaxoSmithKline) in the treatment of solid tumors.

28 Jul 2010

Mediomics receives additional $460,000 in STTR Phase II grant for PINCER protein assay development

Mediomics, LLC has received an additional $460,000 in a renewal of its 2nd year STTR Phase II grant (R42GM079891) from the National Institute of General Medical Sciences. Since 2007, Mediomics has received over one million dollars of STTR funding to develop its quick and sensitive homogenous PINCER™ protein assay. The major goal of the second year project is to further increase the sensitivity of the biosensor.

28 Jul 2010

Medicare to bundle payments for end-stage renal care, reward quality

Medicare payment for end-stage renal disease care may soon be tied to performance and quality measures if a new proposed rule issued by the Centers for Medicare and Medicaid Services is finalized. "If the rule is finalized, ESRD providers that do not meet set standards" - two measures for anemia management and one for hemodialysis quality - "could have their Medicare payments lowered by up to 2 percent starting January 2012, the CMS said" (McKinney, 7/26).

28 Jul 2010

Teenage boys more likely to develop high blood pressure in early adulthood, researchers reveal

Ben-Gurion University of the Negev researchers reveal in a new, large-scale study that "normal" blood pressure at age 17 can still predict hypertension at early adulthood and that teenage boys are three to four times more likely to develop high blood pressure in early adulthood than girls.

28 Jul 2010

CvergenX acquires global rights to InterveneXRT technology for individualization of radiation therapy

Moffitt Cancer Center and CvergenX, Inc., announced today that they have entered into a licensing agreement under which CvergenX has acquired the exclusive worldwide rights to a technology platform that individualizes radiation therapy, InterveneXRT™. Researchers at Moffitt have used gene expression analysis and systems biology to create a radio-sensitivity classification index for individual tumors.

28 Jul 2010

Late preterm births risk infant respiratory illness: Study

Babies born between 34 weeks and 37 weeks gestation are much more likely to have respiratory illness compared to infants born at full term, and their risk of respiratory illness decreases with each additional week of gestation until 38 weeks, researchers report.

28 Jul 2010

Affymetrix to develop, commercialize Axiom Chinese myDesign Genotyping Array

Affymetrix, Inc. today announced that it will develop and commercialize the Axiom Chinese myDesign Genotyping Array, the first product that provides maximum power for genome-wide association studies specifically on Chinese populations.

28 Jul 2010

Insurers test at-home technology, monitoring devices to help cut heart failure hospitalizations

Technology that aims to keep congestive heart failure patients out of the hospital is gaining traction. The idea is for heart patients to take readings like their weight, blood pressure and other key metrics using wireless and other technologies; the data are then transmitted to a case manager or medical care giver.

28 Jul 2010

New study reveals potential role of TGF-β1 in kidney disease

Fibrosis in the kidney is one of the key causes of progressive renal failure. High levels of the inflammatory molecule TGF-β1 in the kidney tubules due to tissue damage can cause fibrosis as well as nephron degeneration, resulting in loss of kidney function. To clarify the mechanisms regulating TGF-β1-mediated renal fibrosis, Koesters et al expressed high levels of TGF-β1 in renal tubules of mice. Nephron degeneration in this system was mediated by decomposition of the tubular cells. These data suggest that TGF-β1 may play a novel role in cell death of renal cells, thus contributing to renal fibrosis.

28 Jul 2010

At summit, AU leaders discuss funding challenges for maternal, child health

African leaders focused on the theme of the 15th African Union (AU) Summit on Sunday: maternal and infant mortality on the continent, PANA/Afrique en ligne reports (7/26).

28 Jul 2010

Scientists develop laser activated carbon nanoparticles for drug, gene delivery

Using chemical "nanoblasts" that punch tiny holes in the protective membranes of cells, researchers have demonstrated a new technique for getting therapeutic small molecules, proteins and DNA directly into living cells.Carbon nanoparticles activated by bursts of laser light trigger the tiny blasts, which open holes in cell membranes just long enough to admit therapeutic agents contained in the surrounding fluid. By adjusting laser exposure, the researchers administered a small-molecule marker compound to 90 percent of targeted cells - while keeping more than 90 percent of the cells alive.

28 Jul 2010

Delirium increases risk of death in older patients

A review and analysis of previous research indicates that delirium in elderly patients is associated with an increased risk of death, dementia, and institutionalization, independent of age, co-existing illnesses or illness severity, according to a study in the July 28 issue of JAMA.

28 Jul 2010

AB SCIEX collaborates with CDC to improve laboratory hormone testing technique

AB SCIEX, a global leader in life science analytical technologies, today announced a collaboration with the Centers for Disease Control and Prevention (CDC) and the CDC Foundation to facilitate the use of mass spectrometry technologies in clinical laboratories for hormone testing. This collaboration is intended to help support the CDC's Hormone Standardization Project for improving the reliability of laboratory results used to help assess disease risk and monitor treatment.

28 Jul 2010

BMJ News reports on Russia's $15.1B health care overhaul

Russia will undergo a $15.1 billion overhaul of its health care sector, including changes to its medical insurance system as well as health care delivery across the country, according to BMJ News. It is "the biggest reform of its troubled healthcare sector - described by Vladimir Putin, the prime minster, as 'deplorable.'" Russian MPs approved the legislation calling for the change in a preliminary vote in in July.

28 Jul 2010

CIHR grants $2.5 million to probe impact of physical activity on breast cancer

Over the next five years, a diverse, multi-disciplinary team of researchers led by Dr. Kerry Courneya of the University of Alberta and Dr. Christine Friedenreich of Alberta Health Services will conduct a series of five large research projects to probe the impacts of physical activity on breast cancer thanks to a $2.5 million team grant over five years from the Canadian Institutes of Health Research (CIHR).

28 Jul 2010

State governments expect tax collections to grow but still face budget gaps

The Wall Street Journal: "State governments expect tax collections to grow for the first time in two years as tax increases and a recovering economy lead to higher collections. But states are still likely to face at least two more years of financial troubles and about half will see gaps in this year's budgets if Congress doesn't extend special Medicaid payments that were part of the 2009 stimulus act, according to a report expected to be released Tuesday by the National Conference of State Legislatures.

28 Jul 2010

Abortion, other issues continue to stoke the politics surrounding health reform

Politico reports that "the issues of health care and abortion" are making the campaign tough for some Democrats. Among the vulnerable Democrats are Reps. Kathleen Dahlkemper, D-Pa.; Steve Driehaus, D-Ohio; and Indiana Reps. Joe Donnelly and Brad Ellsworth, who is running for Senate. "'We are going to do everything we can to point out that Democrats who said they were pro-life caved on the big one,' said Marilyn Musgrave, a former Colorado congresswoman.

28 Jul 2010

Seniors understand very little about health overhaul law, poll finds

The Hill: "The majority of the nation's seniors have little understanding of what the Democrats' newly enacted healthcare law actually does, according to poll results released Monday. The survey, sponsored by the National Council on Aging (NCOA), an advocate for seniors, found that only 17 percent of respondents could answer even half of the 12 questions about key provisions in the law selected by the NCOA.

28 Jul 2010

Maryland sees savings in federal health law, for a while at least

Maryland could spend $829 million less than expected on health care between next year and 2020 because of the federal health overhaul law, according to an analysis by a state-convened committee, The Associated Press/Washington Post reports. "The savings, however, last only until the end of the decade, when the federal law shifts a greater share of financial responsibility for Medicaid expansion to the states." The analysis was produced by the state's Health Care Reform Coordinating Council, a panel created by Gov. Martin O'Malley in March (Witte, 7/26).

28 Jul 2010

Study shows music alleviates anxiety, depression

For decades research has shown that listening to music alleviates anxiety and depression, enhances mood, and can increase cognitive functioning, such as spatial awareness. However, until now, research has not addressed how we listen to music. For instance, is the cognitive benefit still the same if we listen to music whilst performing a task, rather than before it? Further, how does our preference for a particular type of music affect performance? A new study from Applied Cognitive Psychology shows that listening to music that one likes whilst performing a serial recall task does not help performance any more than listening to music one does not enjoy.

28 Jul 2010