Laboratory News and Research

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Researchers call for more accurate renal assessment in stroke patients

Unrecognised renal insufficiency is common among patients with acute stroke and is associated with a significantly increased risk of in-hospital mortality or severe disability at discharge, say researchers.

2 Jun 2016

New checklist from Mettler Toledo helps you keep your lab lean

The successful implementation of “lean manufacturing” in various fields has inspired many businesses to adopt this model in their laboratories as well. However, laboratories have different challenges compared to manufacturing environments.

From Mettler-Toledo International Inc. 1 Jun 2016

RNA molecular dynamics research provides key insights into new treatments for retroviral diseases

New molecular dynamics research into how RNA folds into hairpin-shaped structures called tetraloops could provide important insights into new treatments for retroviral diseases.

1 Jun 2016

Researchers identify potential therapeutic target against oncogenic viral infection

A benign virus normally found in the skin can lead to a type of rare, lethal skin cancer. Specifically, infection by the Merkel cell polyomavirus can lead to Merkel cell carcinoma in immune-compromised individuals.

1 Jun 2016

Altered circadian somatostatin expression linked to bipolar disorder

Results of the first study of its kind to link abnormalities in circadian rhythms to changes in specific neurotransmitters in people with bipolar disorder will be published this week in the journal Biological Psychiatry.

1 Jun 2016

Implanted neuroprosthesis for multi-joint control can improve mobility among stroke survivors

A surgically implanted neuroprosthesis—programmed to stimulate coordinated activity of hip, knee, and ankle muscles—has led to substantial improvement in walking speed and distance in a patient with limited mobility after a stroke, according to a single-patient study in the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists.

1 Jun 2016

Vital compound in common anti-inflammatory drugs can combat cancer, inflammation

Scientists from the Gladstone Institutes have identified a new pathway by which salicylic acid--a key compound in the nonsteroidal anti-inflammatory drugs aspirin and diflunisal--stops inflammation and cancer.

1 Jun 2016

New urine-based diagnostic method may help detect preeclampsia in pregnant women

A team of scientists from the Federal State Budget Institution "Research Center for Obstetrics, Gynecology and Perinatology", Moscow Institute of Physics and Technology, the Emanuel Institute for Biochemical Physics, and the Talrose Institute for Energy Problems of Chemical Physics have developed an approach for a method of non-invasive testing for pregnant women with a serious and complex condition called preeclampsia.

1 Jun 2016

Experts at EAN Congress discuss spread of Zika virus threat across Europe

The Zika epidemic has long assumed global proportions, experts told the Congress of the European Academy of Neurology in Copenhagen. Europe needs to get prepared to deal with the relentless spread of the health threat, in particular with a view to "imported" infection.

31 May 2016

New research uncovers vital role of DHHC9 enzyme in brain circuit development

Research by Dr. Shernaz Bamji, from the University of British Columbia, uncovers the mechanism of action of an enzyme called DHHC9 in the normal development and function of neural networks in the brain.

31 May 2016

Portable breath sensor to detect lifestyle diseases? An interview with Osamu Tsuboi, Fujitsu Laboratories

Generally, it is thought that there is a connection between concentrations of ammonia and liver disease, such as fatty liver and cirrhosis, Helicobacter pylori (H. pylori) infection, and kidney failure.

31 May 2016

Use of next-generation gene sequencing in NICUs may improve diagnosis of rare diseases

The use of next-generation gene sequencing in newborns in neonatal intensive care units (NICUs) may improve the diagnosis of rare diseases and deliver results more quickly to anxious families, according to new research in CMAJ (Canadian Medical Association Journal).

30 May 2016

New study sheds light on link between gut microbiome and the brain

Intestinal bacteria that can boost bravery or trigger multiple sclerosis: An increasing body of research results confirms the importance of the "gut-brain axis" for neurology and indicates that the triggers for a number of neurological diseases may be located in the digestive tract.

30 May 2016

PNNL scientists play central role in National Microbiome Initiative

Scientists at the U.S. Department of Energy's Pacific Northwest National Laboratory are playing a central role as the nation devotes more than $500 million to understand communities of microorganisms and their role in climate science, food production and human health.

28 May 2016

New CRISPR-EZ method makes genome editing much easier in mice

University of California, Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the new gene-editing tool.

28 May 2016

Scientists discover how Zika virus replicates in the placenta

Zika virus can infect and replicate in immune cells from the placenta, without killing them, scientists have discovered. The finding may explain how the virus can pass through the placenta of a pregnant woman, on its way to infect developing brain cells in her fetus.

28 May 2016

Study identifies potential new treatment for subset of gastric cancer patients

Testing cancers for 'addiction' to a gene that boosts cell growth can pick out patients who may respond to a targeted drug under development, a major new study reports.

28 May 2016

Researchers discover ANKRD55 gene linked to multiple sclerosis

The Ikerbasque researcher Koen Vandenbroeck, who heads the Neurogenomiks laboratory which reports to the Achucarro centre and the UPV/EHU-University of the Basque Country, together with other national and international groups, has shown that a genetic variant in the 5q11 chromosome, which is associated with susceptibility to developing multiple sclerosis, greatly regulates a gene known as ANKRD55. ANKRD55 is a gene with an unknown function.

28 May 2016

Salk scientists discover REV-ERBα protein that controls strength of circadian rhythm

At noon every day, levels of genes and proteins throughout your body are drastically different than they are at midnight. Disruptions to this 24-hour cycle of physiological activity are why jet lag or a bad night's sleep can alter your appetite and sleep patterns for days--and even contribute to conditions like heart disease, sleep disorders and cancers.

27 May 2016

Research sheds light on how subtle genetic differences in DMD patients produce variation in symptoms

Johns Hopkins researchers report they have inadvertently found a way to make human muscle cells bearing genetic mutations from people with Duchenne muscular dystrophy (DMD).

27 May 2016

Laboratory News and Research

Researchers call for more accurate renal assessment in stroke patients

New checklist from Mettler Toledo helps you keep your lab lean

RNA molecular dynamics research provides key insights into new treatments for retroviral diseases

Researchers identify potential therapeutic target against oncogenic viral infection

Altered circadian somatostatin expression linked to bipolar disorder

Implanted neuroprosthesis for multi-joint control can improve mobility among stroke survivors

Vital compound in common anti-inflammatory drugs can combat cancer, inflammation

New urine-based diagnostic method may help detect preeclampsia in pregnant women

Experts at EAN Congress discuss spread of Zika virus threat across Europe

New research uncovers vital role of DHHC9 enzyme in brain circuit development

Portable breath sensor to detect lifestyle diseases? An interview with Osamu Tsuboi, Fujitsu Laboratories

Use of next-generation gene sequencing in NICUs may improve diagnosis of rare diseases

New study sheds light on link between gut microbiome and the brain

PNNL scientists play central role in National Microbiome Initiative

New CRISPR-EZ method makes genome editing much easier in mice

Scientists discover how Zika virus replicates in the placenta

Study identifies potential new treatment for subset of gastric cancer patients

Researchers discover ANKRD55 gene linked to multiple sclerosis

Salk scientists discover REV-ERBα protein that controls strength of circadian rhythm

Research sheds light on how subtle genetic differences in DMD patients produce variation in symptoms

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