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Silence Therapeutics extends ongoing research, development collaboration with AstraZeneca

Silence Therapeutics plc is pleased to announce a one-year extension of its ongoing research and development collaboration with AstraZeneca. Under the terms of the agreement, which has progressed well since being signed in July 2007, Silence and AstraZeneca are jointly collaborating in the identification and optimization of five novel siRNA therapeutic molecules addressing respiratory and oncology indications.

14 Jul 2010

Insight into inner functional mechanisms of new bacterial infection target

In any battle, sizing up one's opponent is a critical first step. For researchers fighting a bacterial infection, that means assessing every nook and cranny of the malicious microorganism and identifying which ones to attack.

14 Jul 2010

AD may lead to increased risk of comorbid conditions, research shows

Pfizer Inc., together with its collaborator on the Alzheimer's Immunotherapy Program, Janssen Alzheimer Immunotherapy, presented new research this week at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 from two podium and four poster presentations.

14 Jul 2010

Suicide attempt method affects prognosis

The method used for a suicide attempt is highly significant for the risk of subsequent successful suicide, reveals a long-term study from Karolinska Institutet. The results may be of help in acute risk assessment following a suicide attempt.

14 Jul 2010

Improved delivery methods needed to advance gene therapy strategies for prostate cancer: Review

Improved delivery methods and better testing systems are needed to advance promising gene therapy strategies for treating prostate cancer, according to a series of review articles in Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc.

14 Jul 2010

Therapeutic workbook to facilitate healing process in Haitian children

"When children can tell their stories about a traumatic event in their own words or pictures and at their own speed, healing can begin," says Dr. Jodie Kliman, psychologist and professor at the Massachusetts School of Professional Psychology (MSPP) in Boston. That is why Kliman led MSPP's collaboration with the Children's Psychological Health Center (CPHC) in San Francisco and Ekol Akasya (Acacia School) in Haiti to create a workbook to facilitate that healing process in Haitian children and to identify those at greatest risk for long-term emotional problems.

14 Jul 2010

Protein discovery may lead to new cancer therapies

Researchers funded by the Medical Research Council (MRC) have discovered for the first time that two proteins called Mahjong and Lgl could be star players in helping to identify how the body's own cells fight back against cancer cells.

14 Jul 2010

Skin cell samples may help discover factors behind Parkinson's disease

Researchers are applying new stem cell technology to use skin samples to grow the brain cells thought to be responsible for the onset of Parkinson's disease

14 Jul 2010

New research studies presented at Alzheimer's Association International Conference

The primary therapeutic target in Alzheimer's disease has been the beta amyloid peptide, which clusters outside cells in the brain to form sticky clumps known as plaques. Recently, more attention has been given to the tau protein, which aggregates inside the brain cells of people with Alzheimer's, forming neurofibrillary tangles. Precisely how these proteins interact in causing the disease is unclear.

14 Jul 2010

CRT, MRCT to swap medical discoveries to advance translation of scientific research

Cancer Research Technology and Medical Research Council Technology will 'swap' medical discoveries to accelerate the translation of early scientific research into patient benefit.

14 Jul 2010

Life-or-death 'cell competition' process in mammalian tissue identified

A landmark study by Florida State University biologists, in collaboration with scientists in Britain, is the first to identify a life-or-death "cell competition" process in mammalian tissue that suppresses cancer by causing cancerous cells to kill themselves.

14 Jul 2010

CWRU researchers discover biomarker for early warning of oral cancer

Detecting oral cancer in its earliest stages can save the lives of the nearly 40,500 people diagnosed annually. But early detection has been difficult.

14 Jul 2010

Lung cancer patients likely to suffer significant stigma due to disease's link to smoking: Study

Today, Lung Cancer Alliance highlighted a study, carried out by Ipsos MORI on behalf of The Global Lung Cancer Coalition. The study finds lung cancer patients are likely to suffer significant stigma due to the disease's link to smoking.

14 Jul 2010

Researchers detail innovations that may facilitate earlier detection, improved public health preparedness

With current public health threats ranging from swine flu to bioterrorism to environmental contamination, innovations that better predict disease outbreaks have vast potential to protect the public. In a paper published online in advance of print on July 6 in Emerging Health Threats Journal, public health researchers describe their vision for the future of disease surveillance, detailing innovations on the horizon that may facilitate earlier detection and improved public health preparedness.

14 Jul 2010

Individual genes and networks that play an important role in inflammation, atherosclerosis identified

HemoShear, LLC, a leading developer of innovative, cell-based, human surrogate models for discovery and assessment of new drug compounds, has produced a profile of all of the genes that influence the biology and function of the human artery system. This research has generated valuable information on the entire spectrum of genes that are found in specific cell-types that make up human arteries.

14 Jul 2010

Researcher to lead $14.5M project to fight malaria in Southeast Asia

A researcher in Penn State's College of Agricultural Sciences will lead a seven-year, $14.5 million project to fight malaria in Southeast Asia. Liwang Cui, professor of entomology, is the principal investigator for the Southeast Asia Malaria Research Center, one of 10 International Centers of Excellence for Malaria Research announced by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

14 Jul 2010

The Samuel Waxman Cancer Research Foundation announces research grants totaling $1.54 million

The Samuel Waxman Cancer Research Foundation (SWCRF) has awarded 13 collaborative research grants and 3 individual research grants, totaling $1.54 million. The 16 grants represent a portion of the science grant program at the Foundation, which will award more than $2 million this year to cancer research.

14 Jul 2010

Researchers awarded $3M grant to establish DC D-CFAR

Researchers from institutions across Washington, DC, led by Alan E. Greenberg, M.D., M.P.H., of The George Washington University School of Public Health and Health Services, have been awarded an approximately $3M grant over five years from the National Institutes of Health to establish the District of Columbia Developmental Center for AIDS Research.

14 Jul 2010

Susceptibility to Behcet's disease associated with genes involved in body's immune response

Researchers with the National Institutes of Health have found susceptibility to Behcet's disease, a painful, inflammatory condition, to be associated with genes involved in the body's immune response.

14 Jul 2010

Drugs taken for common medical conditions cause long term cognitive impairment in older adults: Study

Drugs commonly taken for a variety of common medical conditions including insomnia, allergies, or incontinence negatively affect the brain causing long term cognitive impairment in older African-Americans, according to a study appearing in the July 13, 2010 print issue of Neurology, the medical journal of the American Academy of Neurology.

14 Jul 2010

Research News and Research

Silence Therapeutics extends ongoing research, development collaboration with AstraZeneca

Insight into inner functional mechanisms of new bacterial infection target

AD may lead to increased risk of comorbid conditions, research shows

Suicide attempt method affects prognosis

Improved delivery methods needed to advance gene therapy strategies for prostate cancer: Review

Therapeutic workbook to facilitate healing process in Haitian children

Protein discovery may lead to new cancer therapies

Skin cell samples may help discover factors behind Parkinson's disease

New research studies presented at Alzheimer's Association International Conference

CRT, MRCT to swap medical discoveries to advance translation of scientific research

Life-or-death 'cell competition' process in mammalian tissue identified

CWRU researchers discover biomarker for early warning of oral cancer

Lung cancer patients likely to suffer significant stigma due to disease's link to smoking: Study

Researchers detail innovations that may facilitate earlier detection, improved public health preparedness

Individual genes and networks that play an important role in inflammation, atherosclerosis identified

Researcher to lead $14.5M project to fight malaria in Southeast Asia

The Samuel Waxman Cancer Research Foundation announces research grants totaling $1.54 million

Researchers awarded $3M grant to establish DC D-CFAR

Susceptibility to Behcet's disease associated with genes involved in body's immune response

Drugs taken for common medical conditions cause long term cognitive impairment in older adults: Study

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