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Scientists uncover variations in X chromosome inactivation in early passages of female embryonic stem cells

Human embryonic stem cells hold great promise for studying and treating disease and for the practice of regenerative medicine. However, more must be learned to ensure the cells that may one day be transplanted into humans are safe.

28 Jun 2010

New center opens for vets with traumatic brain injuries and psychological issues

"The $65 million medical center, which opened Thursday, is devoted exclusively to helping members of the military who suffer from traumatic brain injuries, PTSD and other psychological issues. Its opening comes on the heels of a flurry of congressional criticism and reports claiming that soldiers with traumatic brain injuries often do not have their conditions diagnosed and are forced to wade through the vast bureaucracy of the Defense Centers of Excellence for Psychological Help and Traumatic Brain Injury, which is charged with their treatment."

28 Jun 2010

Hospital for Special Surgery announces receipt of $5M commitment from CA Technologies

Hospital for Special Surgery announced the receipt of a $5 million commitment from CA Technologies, an IT management software and solutions company, at its 27th Annual Tribute Dinner at the Waldorf Astoria on June 21, 2010.

28 Jun 2010

G8 leaders to discuss economic policy, developing world, maternal and child health, Haitian rebuilding

Ahead of the G8 summit, which begins Friday in Canada, "leaders engaged in a series of dueling letters and interviews that exposed their conflicts" in how to foster global economic recovery, the Associated Press reports.

28 Jun 2010

Antioxidant therapy may prevent long-lasting cognitive impairment in cerebral malaria: Research

Using an experimental mouse model for malaria, an international group of scientists has discovered that adding antioxidant therapy to traditional antimalarial treatment may prevent long-lasting cognitive impairment in cerebral malaria. Their findings were published online June 24, 2010, in the journal PLoS Pathogens.

28 Jun 2010

Data on MetAP2 inhibitors for treatment of obesity presented at ADA 2010

Zafgen, Inc., a pharmaceutical company pioneering novel obesity therapeutics to help the body regain and sustain a lean, healthy state by targeting imbalances in fat metabolism, today announced data on ZGN-201, a prototype methionine aminopeptidase 2 inhibitor, for the treatment of obesity. Preclinical studies demonstrate MetAP2 inhibition eliminates excess body weight through the regulation of fat metabolism and food intake, and normalizes glucose tolerance in animal models.

28 Jun 2010

WCO signs declaration, vows to crack down on counterfeit drug industry

World Customs Organization Secretary General Kunio Mikuriya on Thursday signed a declaration vowing his group's commitment to crack down on the counterfeit drug industry, PBS NewsHour's "The Rundown" blog reports. The piece examines the growing threat of counterfeit medications worldwide and efforts to clamp down on the distribution of such drugs (Miller, 6/24).

28 Jun 2010

National Intrepid Center of Excellence to treat veterans with traumatic brain injury

The U.S. Department of Defense and the Intrepid Fallen Heroes Fund on June 24 officially dedicated the National Intrepid Center of Excellence, a new 72,000-square-foot medical facility in Bethesda, Md., dedicated to researching, diagnosing and treating traumatic brain injury in U.S. military personnel.

28 Jun 2010

Researchers discover genetic links to kidney failure, diabetic kidney disease

Researchers at the Translational Genomics Research Institute will make two presentations at this week's 70th Scientific Sessions of the American Diabetes Association, June 25-29, in Orlando, Florida.

28 Jun 2010

Senate fails to pass 'extenders' bill, state Medicaid funding

After a bill to extend jobs and economic relief programs failed for the third time in the Senate Thursday, Majority Leader Harry Reid announced he would withdraw the bill, Politico reports. The legislation included financial relief for states, including billions to support Medicaid programs.

28 Jun 2010

New preclinical data of XOMA 052 in animal model of Type 2 diabetes to be presented at ADA 2010

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, will be presenting new preclinical data in an animal model of Type 2 diabetes in which its anti-inflammatory therapeutic antibody candidate, XOMA 052, was used as monotherapy and in combination with the marketed anti-diabetic drugs exendin-4 (Byetta) or sitagliptin (Januvia).

28 Jun 2010

Report highlights economic growth, potential in Africa

A report from the consulting firm McKinsey & Company said "global businesses cannot afford to ignore the potential" in African economies, the New York Times reports.

28 Jun 2010

Mass. Legislature denies requests to trim municipal health benefits; N.Y. ordered to transfer people with mental Illness out of institutional group homes

"The state's public employee unions won a major victory this week when the Legislature abandoned efforts to allow cities and towns to trim generous health care benefits enjoyed by thousands of municipal employees, retirees, and elected officials. The decision by lawmakers not to address the issue in next year's budget means the Legislature will almost certainly not act on it this year, setting the stage for mayors and other municipal officials to take their case directly to voters in a ballot initiative for 2012" (Murphy, 6/25).

28 Jun 2010

Mechanism that regulates stem-cell differentiation in mice may trigger degenerative disease in humans: Research

A mechanism that regulates stem-cell differentiation in mice testes suggests a similar process that may trigger degenerative disease in humans, according to a Penn State College of Agricultural Sciences reproductive physiologist.

28 Jun 2010

Kansas doctor and wife found guilty of prescribing painkillers, causing deaths

"A federal jury Thursday found a Kansas doctor and his wife guilty of conspiring to profit from illegally prescribing painkillers to dozens of patients who later died, in a case highlighting medical treatment of chronic pain sufferers and prescription drug abuse."

28 Jun 2010

Phase 2b clinical trial data of SGLT2 inhibitor in patients with type 2 diabetes presented at ADA 2010

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. announced today that canagliflozin, an investigational, oral, selective sodium-glucose transporter-2 inhibitor, improved glycemic control, and was also associated with a decrease in body weight, in a Phase 2b dose-ranging trial in patients diagnosed with type 2 diabetes who were concurrently treated with metformin. The data were presented at the 70th American Diabetes Association Scientific Sessions.

28 Jun 2010

Insurer sees coming health insurer 'oligopoly,' doctors band together on system changes

Bloomberg Businessweek reports that health insurer WellPoint's investor-relations chief said Thursday that health insurers are "moving towards an oligopoly" accelerated by the new law. "New regulations on administrative spending and premium increases will push some independent insurers out of business or into deals with bigger rivals, said Michael Kleinman, vice president for investor relations, at a Wells Fargo & Co. conference in Boston.

28 Jun 2010

Additional results from BLISS-76 Phase 3 trial of BENLYSTA presented at International Congress on SLE

Human Genome Sciences, Inc. today announced the presentation of additional results from BLISS-76, one of two pivotal Phase 3 trials of BENLYSTA (belimumab) in seropositive patients with systemic lupus erythematosus. The additional data will be presented in Vancouver at the 9th International Congress on Systemic Lupus Erythematosus on Friday and Saturday, June 25-26.

28 Jun 2010

New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

The cause of diabetes during pregnancy is directly controlled by serotonin, a chemical produced by the body and normally known as a neurotransmitter, and is influenced by the amount of protein in the mother's diet early in pregnancy, according to new findings of an international team led by researchers at UCSF.

28 Jun 2010

High-risk health insurance pools opening soon

News outlets examine how states are coping with covering hard-to-insure people, confusion about insuring young adults and a COBRA subsidy extension.

28 Jun 2010

Research News and Research

Scientists uncover variations in X chromosome inactivation in early passages of female embryonic stem cells

New center opens for vets with traumatic brain injuries and psychological issues

Hospital for Special Surgery announces receipt of $5M commitment from CA Technologies

G8 leaders to discuss economic policy, developing world, maternal and child health, Haitian rebuilding

Antioxidant therapy may prevent long-lasting cognitive impairment in cerebral malaria: Research

Data on MetAP2 inhibitors for treatment of obesity presented at ADA 2010

WCO signs declaration, vows to crack down on counterfeit drug industry

National Intrepid Center of Excellence to treat veterans with traumatic brain injury

Researchers discover genetic links to kidney failure, diabetic kidney disease

Senate fails to pass 'extenders' bill, state Medicaid funding

New preclinical data of XOMA 052 in animal model of Type 2 diabetes to be presented at ADA 2010

Report highlights economic growth, potential in Africa

Mass. Legislature denies requests to trim municipal health benefits; N.Y. ordered to transfer people with mental Illness out of institutional group homes

Mechanism that regulates stem-cell differentiation in mice may trigger degenerative disease in humans: Research

Kansas doctor and wife found guilty of prescribing painkillers, causing deaths

Phase 2b clinical trial data of SGLT2 inhibitor in patients with type 2 diabetes presented at ADA 2010

Insurer sees coming health insurer 'oligopoly,' doctors band together on system changes

Additional results from BLISS-76 Phase 3 trial of BENLYSTA presented at International Congress on SLE

New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

High-risk health insurance pools opening soon

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