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Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

Most drugs operate via the membranes that surround the body's cells. A study by researchers at Karolinska Institutet in Sweden has now mapped the structure and mechanism of MGST2, a membrane enzyme that, amongst other things, plays a part in chronic inflammation and cancer.

20 Mar 2021

FDA authorizes first machine learning-based COVID-19 non-diagnostic screening device

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the first machine learning-based Coronavirus Disease 2019 (COVID-19) non-diagnostic screening device that identifies certain biomarkers that are indicative of some types of conditions, such as hypercoagulation (a condition causing blood to clot more easily than normal).

20 Mar 2021

COVID-19 in pregnancy associated with preeclampsia, stillbirth, preterm birth

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in pregnancy is associated with preeclampsia, stillbirth, preterm birth and other adverse outcomes, found new research published in CMAJ.

20 Mar 2021

COVID-19 patients have higher risk of stroke, finds study

New research found patients hospitalized with COVID-19 had a higher risk of stroke, compared with patients who had similar infectious conditions such as influenza and sepsis in prior studies.

19 Mar 2021

Endovascular therapy more prevalent among stroke patients, yet racial differences persist

Mechanical removal of blood clots causing a stroke is increasing, yet racial differences in treatment persist, according to late-breaking science presented today at the American Stroke Association's International Stroke Conference 2021.

19 Mar 2021

Study reveals worsening health profiles in Gen X and Gen Y

Recent generations show a worrying decline in health compared to their parents and grandparents when they were the same age, a new national study reveals.

19 Mar 2021

Developing a COVID-19 vaccine using inactivated E. coli

A team of researchers inactivated whole-cell E.coli with a reduced genome and utilized this to express coronavirus-specific fusion peptides, demonstrating a potent anamnestic response.

19 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

The case for donating US Covid vaccines overseas

A Senate committee grilled federal officials about the shortage of vaccines to protect Americans against a pandemic virus. Two months later, the U.S. public had lost interest in the virus, and millions of vaccines were sitting in warehouses — although poor countries still needed them.

19 Mar 2021

Study examines efficacy of Pfizer-BioNTech mRNA COVID-19 vaccine across demographic groups

A new study examines data from Israel's vaccination campaign to assess the efficacy of the Pfizer-BioNTech mRNA vaccine across different demographics.

19 Mar 2021

New proteomics method helps confirm COVID-19 transmission from mother to fetus

Researchers from Skoltech were part of a research consortium studying a case of vertical COVID-19 transmission from mother to her unborn child that resulted in major complications in the pregnancy, premature birth and death of the child.

19 Mar 2021

Study: Mobile stroke units reduce disability, improve outcomes in stroke patients

Stroke patients treated via a mobile stroke unit (MSU) received clot-busting medications faster and more often - and recovered significantly better than patients who receive regular emergency care by standard ambulance.

19 Mar 2021

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Atypical teratoid rhabdoid tumor (ATRT) is a rare brain tumor that predominantly occurs in young children. Scientists at St. Jude Children's Research Hospital used data from two clinical trials to study the molecular groups of ATRT and correlate them with clinical outcomes.

19 Mar 2021

Alliance for Cancer Gene Therapy provides new opportunity to develop cancer cell and gene therapies

Alliance for Cancer Gene Therapy wants to change the C-word from Cancer to Cure -- building on the life changing success of CAR-T therapies for blood cancers, the organization is now focused on the urgent need to translate this success into therapies to fight more types of cancer, such as solid tumor cancers.

19 Mar 2021

N-terminal domain antibodies play a key role in COVID immunity

Scientists are learning that a lesser-studied region on the pandemic coronavirus is recognized by COVID-19 infection-fighting antibodies. These antibodies were identified in blood samples from previously infected patients, and were found to potently prevent the virus from infecting cells.

19 Mar 2021

Pancreatic cancer cells use adaptive mechanisms to avoid death by starvation

In new findings published online March 18, 2021 in the journal Cancer Cell, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Moores Cancer Center, describe how pancreatic cancer cells use an alternative method to find necessary nutrients, defying current therapies, to help them grow and spread.

19 Mar 2021

Malfunctioning blood-brain barrier is linked to benign forgetfulness of aging

Have you forgotten where you laid your keys? Ever wondered where you had parked your car? Or having trouble remembering the name of the new neighbor? Unfortunately, these things seem to get worse as one gets older.

19 Mar 2021

Mass vaccination needed to protect against future resurgences of COVID-19

The first long-term seroprevalence study of residents in Wuhan, China, has found that 6.9% of people in the city had antibodies against COVID-19 in April 2020, and 82% of these people had an asymptomatic infection.

19 Mar 2021

Anti-inflammatory therapies may help prevent heart disease in people with age-related blood condition

Therapies that soothe inflammation could be an effective way to prevent heart disease in people with a common age-related blood condition, according to a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons.

18 Mar 2021

Antidiabetic drug could help reduce chronic inflammation in people living with HIV

Metformin, a drug used to treat type-2 diabetes, could help reduce chronic inflammation in people living with HIV (PLWH) who are being treated with antiretroviral therapy (ART), according to researchers at the University of Montreal Hospital Research Centre.

18 Mar 2021

Blood News and Research

Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

FDA authorizes first machine learning-based COVID-19 non-diagnostic screening device

COVID-19 in pregnancy associated with preeclampsia, stillbirth, preterm birth

COVID-19 patients have higher risk of stroke, finds study

Endovascular therapy more prevalent among stroke patients, yet racial differences persist

Study reveals worsening health profiles in Gen X and Gen Y

Developing a COVID-19 vaccine using inactivated E. coli

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

The case for donating US Covid vaccines overseas

Study examines efficacy of Pfizer-BioNTech mRNA COVID-19 vaccine across demographic groups

New proteomics method helps confirm COVID-19 transmission from mother to fetus

Study: Mobile stroke units reduce disability, improve outcomes in stroke patients

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Alliance for Cancer Gene Therapy provides new opportunity to develop cancer cell and gene therapies

N-terminal domain antibodies play a key role in COVID immunity

Pancreatic cancer cells use adaptive mechanisms to avoid death by starvation

Malfunctioning blood-brain barrier is linked to benign forgetfulness of aging

Mass vaccination needed to protect against future resurgences of COVID-19

Anti-inflammatory therapies may help prevent heart disease in people with age-related blood condition

Antidiabetic drug could help reduce chronic inflammation in people living with HIV

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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