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Epigenomics receives FDA approval for Epi proColon®

Epigenomics AG, the German-American cancer molecular diagnostics company, has announced that the U.S. Food and Drug Administration (FDA) has approved the Company’s lead product, Epi proColon®, the first and only FDA-approved blood-based colorectal cancer screening test.

14 Apr 2016

UC San Diego receives NIH grant to establish interdisciplinary center to combat antibiotic resistance

Researchers at University of California, San Diego School of Medicine have received a five-year, $9.5-million award from the National Institute of Allergy and Infectious Diseases at the National Institutes of Health to establish an interdisciplinary center to define the systems biology of antibiotic resistance. The program will be led by Bernhard Palsson, PhD, Distinguished Professor of Bioengineering and Pediatrics, and Victor Nizet, MD, professor of pediatrics and pharmacy.

13 Apr 2016

Novel biochemical method can extend lifetime of implantable medical devices

Blood-contacting implantable medical devices, such as stents, heart valves, ventricular assist devices, and extracorporeal support systems, as well as vascular grafts and access catheters, are used worldwide to improve patients' lives. However, these devices are prone to failure due to the body's responses at the blood-material interface; clots can form and inflammatory reactions can prevent the device from performing as indicated. Currently, when this occurs, the only solution is to replace the device.

13 Apr 2016

Study reveals TRPV2 protein as new target for chronic pain, cancer treatments

In a recent paper published in Nature Communications, a group of Case Western University School of Medicine researchers presented their discovery of the full-length structure of a protein named Transient Receptor Potential Vanilloid subtype 2 (TRPV2).

13 Apr 2016

Combination of sugar and polyphenols may prevent occurrence of neurodegenerative disease

Catherine Aaron and Gabrielle Beaudry were 17 when they knocked on the door of the laboratory of Alex Parker, a neuroscience researcher at the University of Montreal Hospital Research Centre. While students at Collège Jean-de-Brébeuf in Montreal, they were looking for a mentor for an after-school research project. Two and half years later, the results of this scientific adventure were published today in the Journal of Agricultural and Food Chemistry.

13 Apr 2016

Next generation analytical ultracentrifuge to be launched by Beckman Coulter at Analytica

Beckman Coulter Life Sciences is to launch the new Optima AUC at this year’s Analytica: 25th International Trade Fair.

From Beckman Coulter Life Sciences - Centrifugation 13 Apr 2016

Scientists use FAN1 knockout mice to refine detailed mechanisms involved in damaged DNA repair

Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell--sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet over the course of a life moving through this world, our DNA does get damaged, and our cells have a host of complicated repair mechanisms to deal with such injuries.

13 Apr 2016

Inserm study reveals potential of secondary system to improve heart function

Heart failure affects over one million people in France. Although the blood system is the first to have been explored for the purpose of improving heart function, a study by Inserm has revealed the potential of a secondary system that had previously received scant attention.

13 Apr 2016

Aspirin resistance signals increased stroke severity

Stroke severity and infarct volume are significantly increased among patients who become resistant to aspirin, show study findings published in Neurology.

12 Apr 2016

Manipulation of signals in nervous system can enhance recovery after traumatic injury

Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. They also found that manipulating these signals can enhance the return of function.

12 Apr 2016

Bacteroidia pilins prevalent in human gut and mouth form new type of pili to cling to hosts

Many bacteria interact with their environment through hair-like structures known as pili, which attach to and help mediate infection of host organisms, among other things. Now a U.S.-Japanese research team, including scientists from the Department of Energy's SLAC National Accelerator Laboratory, has discovered that certain bacteria prevalent in the human gut and mouth assemble their pili in a previously unknown way - information that could potentially open up new ways of fighting infection.

12 Apr 2016

Biopsy of submandibular gland can help identify pathology of Parkinson's disease, dementia with Lewy bodies

Accurate diagnosis of Parkinson's disease, and the related disease "dementia with Lewy bodies," can be difficult in the early stages of both conditions. While brain biopsies can be more accurate, the risk of complications has been considered too high. New research published in the Journal of Parkinson's Disease indicates that a biopsy of the submandibular gland can help identify the same pathology that is seen in the brain, providing some of the increased accuracy of brain biopsy, but not the increased risk.

12 Apr 2016

Distribution of c-Myc protein during asymmetric cell division influences fate, roles of activated T cells

The fates of immune cells can be decided at the initial division of a cell. Researchers at St. Jude Children's Research Hospital have discovered that the production of daughter cells with different roles in the immune system is driven by the lopsided distribution of the signaling protein c-Myc. Nudging c-Myc in one direction or the other could make vaccines more effective or advance immunotherapies for cancer treatment. The research appears online today in the scientific journal Nature.

12 Apr 2016

Dual-acting hybrid drug could be a promising new weapon against drug-resistant malaria

A combination of artemisinin and another drug (artemisinin combination therapy, ACT) is currently the best malaria treatment recommended by the World Health Organization.

12 Apr 2016

Mild traumatic brain injury can affect quality of parent-child relationships

A study published in the Journal of Neuropsychology, reveals the adverse effects of mild traumatic brain injury (mTBI) on the quality parent-child relationships. The young brain is particularly vulnerable to injury and one of the first visible signs of social difficulties in young children is a decline in their relationship with their parents. Parents should watch for emotional and behavioural changes in their children.

12 Apr 2016

New data from studies evaluating diagnostic tools, therapies for infectious diseases released at ECCMID 2016

New data from ten late-breaking abstracts is released at ECCMID 2016 – the annual meeting of the European Society of Clinical Microbiology and Infectious Disease.

12 Apr 2016

Researchers develop new technology to tailor grafted tissues

Researchers from the Technion-Israel Institute of Technology and colleagues in the U.S. have developed technology to tailor grafted tissues that can respond to certain natural forces affecting blood vessels.

12 Apr 2016

Porvair Sciences to launch new microplate for genomics at Analytica 2016

Porvair Sciences has announced that it will launch an exciting new microplate for genomics sample preparation at the forthcoming Analytica 2016 exhibition in Munich, Germany.

From Porvair Sciences Limited 12 Apr 2016

Transcranial direct current stimulation can allow faster comprehension of meaningful word combinations

How the human brain processes the words we hear and constructs complex concepts is still somewhat of a mystery to the neuroscience community. Transcranial direct current stimulation (tDCS) can alter our language processing, allowing for faster comprehension of meaningful word combinations, according to new research from the department of Neurology the Perelman School of Medicine at the University of Pennsylvania. The work is published in the Journal of Neuroscience.

11 Apr 2016

Advanced assay offers better sensitivity for detecting a prion disease affecting elk

Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a family of rare progressive, neurodegenerative illnesses that affect both humans and animals. TSE surveillance is important for public health and food safety because TSEs have the potential of crossing from animals to humans, as seen with the spread of mad cow disease, or bovine spongiform encephalopathy (BSE). A study in The Journal of Molecular Diagnostics describes an advanced assay that offers better sensitivity than currently available tests for detecting a prion disease affecting elk.

11 Apr 2016

Laboratory News and Research

Epigenomics receives FDA approval for Epi proColon®

UC San Diego receives NIH grant to establish interdisciplinary center to combat antibiotic resistance

Novel biochemical method can extend lifetime of implantable medical devices

Study reveals TRPV2 protein as new target for chronic pain, cancer treatments

Combination of sugar and polyphenols may prevent occurrence of neurodegenerative disease

Next generation analytical ultracentrifuge to be launched by Beckman Coulter at Analytica

Scientists use FAN1 knockout mice to refine detailed mechanisms involved in damaged DNA repair

Inserm study reveals potential of secondary system to improve heart function

Aspirin resistance signals increased stroke severity

Manipulation of signals in nervous system can enhance recovery after traumatic injury

Bacteroidia pilins prevalent in human gut and mouth form new type of pili to cling to hosts

Biopsy of submandibular gland can help identify pathology of Parkinson's disease, dementia with Lewy bodies

Distribution of c-Myc protein during asymmetric cell division influences fate, roles of activated T cells

Dual-acting hybrid drug could be a promising new weapon against drug-resistant malaria

Mild traumatic brain injury can affect quality of parent-child relationships

New data from studies evaluating diagnostic tools, therapies for infectious diseases released at ECCMID 2016

Researchers develop new technology to tailor grafted tissues

Porvair Sciences to launch new microplate for genomics at Analytica 2016

Transcranial direct current stimulation can allow faster comprehension of meaningful word combinations

Advanced assay offers better sensitivity for detecting a prion disease affecting elk

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