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New tool to expedite research ethics review during emergency preparedness

A new emergency review tool will help research ethics boards and institutions to expedite research while respecting the procedures of ethics reviews, states an article in CMAJ.

8 Jun 2010

CMI must implement payment initiatives to improve health care delivery, reduce spending: New article

The new Center for Medicare and Medicaid Innovation must be inclusive and flexible in developing and implementing payment initiatives, continuously monitor their impact, and rapidly disseminate them if they appear to be successful, in order to realize the potential for improved health care delivery and reduced spending, according to a new Health Affairs article by Commonwealth Fund researchers.

8 Jun 2010

Experimental drug that targets genetic makeup of tumor shows early signs of efficacy against medulloblastomas

Researchers from St. Jude Children's Research Hospital and the Pediatric Brain Tumor Consortium (PBTC) presented at the American Society of Clinical Oncology the findings of a pediatric brain tumor study using an experimental drug that targets the underlying genetic makeup of the tumor. The research focused on a new way to attack the tumors by blocking the Hedgehog pathway that is linked to approximately 20 percent of medulloblastomas.

8 Jun 2010

Sleep extension helps athletes achieve optimal performance: Research

Getting extra sleep over an extended period of time improves athletic performance, alertness and mood, according to a research abstract that will be presented Tuesday, June 8, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

8 Jun 2010

$Phase 2 Study: NKTR-102 holds great therapeutic potential for women with platinum-resistant/refractory ovarian cancer$

Phase 2 Study: NKTR-102 holds great therapeutic potential for women with platinum-resistant/refractory ovarian cancer

Nektar Therapeutics today announced positive results from a Phase 2 clinical study evaluating single-agent NKTR-102 in women with platinum-resistant/refractory ovarian cancer. A total of 68 patients were enrolled with platinum-resistant disease, half of whom were platinum refractory. All 68 patients were evaluable for the primary endpoint of objective response rate using Gynecologic Cancer InterGroup criteria, which is a combination of response by tumor imaging (RECIST) and/or ovarian cancer biomarker (CA-125) criteria.

8 Jun 2010

Regular exercise reduces fall risk

Remaining physically fit and sticking to a regular exercise routine could lower your risk of taking a tumble, finds a new research study.

8 Jun 2010

Cegedim Dendrite reports 2010 survey results of bio-pharmaceutical industry's market access

Cegedim Dendrite, the leading provider of CRM software and healthcare data to the bio-pharmaceutical industry, today announces the results of The Cegedim Dendrite Market Access Industry Report 2010; a market research survey conducted in May this year across nearly 200 European executives from marketing, market access, market research and sales departments within bio-pharmaceutical organisations.

8 Jun 2010

Findings from Abraxis BioScience's phase 3 ABRAXANE trial in patients with NSCLC presented at ASCO

Abraxis BioScience, Inc. announced today that findings from their phase 3 randomized trial of nanoparticle albumin bound driven chemotherapy, nab-paclitaxel (ABRAXANE for Injectable Suspension; paclitaxel albumin protein-bound particles for injectable suspension) plus carboplatin, showed a statistically significant 31 percent improvement in overall response rate when compared with Taxol (paclitaxel) injection plus carboplatin in the first-line treatment of patients with non-small cell lung cancer.

8 Jun 2010

Nurses working 12-hour shifts struggle to remain vigilant during successive shifts: Research

A small percentage of nurses struggle to remain vigilant during successive 12-hour shifts, according to a research abstract that will be presented Tuesday, June 8, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

8 Jun 2010

Researchers decipher how mast cells set immune defense on right track

In the event of an infection, the immune system releases messenger substances. These molecules can either activate immune cells to defeat invading pathogens, or inhibit them to prevent an excessive immune reaction. For this, the immune system has to decide very quickly what mixture of activating and inhibiting messenger molecules leads to a successful defence.

8 Jun 2010

Updated HIV treatment guidelines may benefit individuals infected with HIV: Researchers

Researchers from the BC Centre for Excellence in HIV/AIDS and the University of British Columbia today released a comprehensive study revealing that the 2008 IAS-USA therapy guidelines for commencing HIV treatment would create significant benefits for individuals infected with HIV and society as a whole.

8 Jun 2010

Low LDL cholesterol levels increase life expectancy

A University of Minnesota study definitively shows that those with decreased LDL cholesterol levels can count on an increased life expectancy. The research is published in the May 24 edition of the Annals of Surgery.

8 Jun 2010

Polaris' ADI-PEG 20 novel anticancer drug inhibits growth of metastatic melanoma cells: Study

Physicians attending the annual meeting of the American Society of Clinical Oncology (ASCO) presented evidence that pegylated arginine deiminase (ADI-PEG 20), a novel anticancer drug that targets ASS(-) tumors, and which is being developed and manufactured by Polaris Group, was effective in inhibiting the growth of metastatic melanoma cells.

8 Jun 2010

Day shifts allow workers to get more sleep than night shifts: Study

Regulations that limit the number of hours worked also should provide guidance for shift start times to maximize workers' sleep opportunity and minimize the risk of on-the-job fatigue, according to a research abstract that will be presented Tuesday, June 8, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

8 Jun 2010

Combat in Iraq associated with post-deployment PTSD, depression in 8.5 to 14% of soldiers

Between 8.5 percent and 14 percent of soldiers returning from Iraq report serious functional impairment due to either posttraumatic stress disorder or depression, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

8 Jun 2010

Children and teens with moderate to severe OSA have lower academic grades: Research

The average academic grades of children and teens with moderate to severe obstructive sleep apnea are worse than the grades of students who have no sleep-disordered breathing, according to a research abstract that will be presented Tuesday, June 8, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

8 Jun 2010

Research findings open door to development of new therapies for lymphomas, leukemias

Scripps Research Institute scientists have discovered a new way to target and destroy a type of cancerous cell. The findings may lead to the development of new therapies to treat lymphomas, leukemias, and related cancers.

8 Jun 2010

Researchers discover RAF oncogene that may drive aggressive forms of prostate cancer

The Prostate Cancer Foundation announced today that researchers at the University of Michigan Comprehensive Cancer Center have discovered the RAF oncogene that drives fatal melanomas may also drive the aggressive forms of prostate cancer in the clinic.

8 Jun 2010

Nighttime noise disturbs sleep, impairs neurobehavioral performance in the morning: Research

Nighttime noise from nearby road traffic, passing trains and overhead planes disturbs sleep and impairs morning performance, according to a research abstract that will be presented Tuesday, June 8, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC.

8 Jun 2010

Evidence-based oral health guidelines for pregnant women

Health care providers now have evidence-based guidelines to emphasize the importance of pregnant women maintaining good oral health care and the safety of providing appropriate treatment during pregnancy as published in the June Journal of the California Dental Association.

8 Jun 2010

Research News and Research

New tool to expedite research ethics review during emergency preparedness

CMI must implement payment initiatives to improve health care delivery, reduce spending: New article

Experimental drug that targets genetic makeup of tumor shows early signs of efficacy against medulloblastomas

Sleep extension helps athletes achieve optimal performance: Research

Phase 2 Study: NKTR-102 holds great therapeutic potential for women with platinum-resistant/refractory ovarian cancer

Regular exercise reduces fall risk

Cegedim Dendrite reports 2010 survey results of bio-pharmaceutical industry's market access

Findings from Abraxis BioScience's phase 3 ABRAXANE trial in patients with NSCLC presented at ASCO

Nurses working 12-hour shifts struggle to remain vigilant during successive shifts: Research

Researchers decipher how mast cells set immune defense on right track

Updated HIV treatment guidelines may benefit individuals infected with HIV: Researchers

Low LDL cholesterol levels increase life expectancy

Polaris' ADI-PEG 20 novel anticancer drug inhibits growth of metastatic melanoma cells: Study

Day shifts allow workers to get more sleep than night shifts: Study

Combat in Iraq associated with post-deployment PTSD, depression in 8.5 to 14% of soldiers

Children and teens with moderate to severe OSA have lower academic grades: Research

Research findings open door to development of new therapies for lymphomas, leukemias

Researchers discover RAF oncogene that may drive aggressive forms of prostate cancer

Nighttime noise disturbs sleep, impairs neurobehavioral performance in the morning: Research

Evidence-based oral health guidelines for pregnant women

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