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Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

Melanopsin (OPN4) is a light-sensing protein found in skin and retina cells. A new study conducted at the University of São Paulo (USP) in Brazil suggests that OPN4 can also participate in the development and progression of melanoma, the most aggressive type of skin cancer.

10 Aug 2022

A broad sarbecovirus-neutralizing antibody cocktail

Researchers present a rational approach for identifying SARS-CoV-2 receptor-binding domain-targeted broad neutralizing antibody cocktails.

9 Aug 2022

Scientists explore ex utero generation of post-gastrulation synthetic embryos

Researchers showed that post-gastrulation synthetic embryos (sEmbryos) could be synthesized outside the uterus using mouse naive embryonic stem cells (ESCs).

9 Aug 2022

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Researchers evaluated the comparative pathogenicity of SARS-CoV-2 Omicron sub-variants BA.1, BA.2, and BA.5, in vitro and in vivo.

9 Aug 2022

Researchers unravel a novel molecular target of eicosapentaenoic acid

Eicosapentaenoic acid (EPA) is an essential nutrient belonging to the omega-3 group of polyunsaturated fatty acids (PUFAs). As the human body cannot synthesize PUFAs, dietary supplements containing EPA are required for normal physiological functions. Found abundantly in natural sources like fish, hemp oil, and linseed oil, EPA is known to exhibit anti-inflammatory, neuroprotective, and cardiovascular protective activities.

9 Aug 2022

Serbia's genome center monitors potential virus mutations to facilitate more effective COVID-19 control

In partnership with BGI Genomics from China, Serbia's first genome sequencing center, opened in December 2021, is monitoring potential virus mutations to facilitate more effective COVID-19 control and accelerating access to genomics to enhance health outcomes.

9 Aug 2022

COVID-19 vaccination increases antibodies in breast milk significantly

Anti-SARS-CoV-2 antibodies in breast milk capable of neutralizing both an early pandemic SARS-CoV-2 isolate and Omicron variant.

8 Aug 2022

Study tests equine polyclonal antibodies against SARS-CoV-2 variants

A recent study published tested equine polyclonal antibodies against SARS-CoV-2.

8 Aug 2022

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

A recent paper describes the use of aprotinin, a protease inhibitor that works across several pathways, to reduce the severity of COVID-19.

8 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

New dual-plasmid editing system for DNA-based information rewriting in vivo

DNA-based information is a new interdisciplinary field linking information technology and biotechnology.

5 Aug 2022

Researchers discover two signaling pathways that are downregulated in human hearts after birth

Published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth.

4 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN Bio 3 Aug 2022

Hemopurifier containing Galanthus nivalis resin removes SARS-CoV-2 variants

Scientists hypothesize that the GNA affinity resin would remain effective against SARS-CoV-2 variants.

2 Aug 2022

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/Medical University of Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder.

2 Aug 2022

Researchers characterize a novel gene likely to cause neurological disorders in humans

A multidisciplinary study led by Vanja Nagy (LBI-RUD/CeMM/MedUni Vienna) and Josef Penninger (UBC/IMBA) characterized a novel gene, known as FIBCD1, to be likely causative of a new and rare neurodevelopmental disorder. Using data from two young patients with neurological symptoms, the researchers from both groups found evidence of a novel function for the FIBCD1 gene in the brain, and a potentially pivotal role in diseases such as autism, ADHD, schizophrenia, and neurodegenerative disorders including Alzheimer's. The study makes an important contribution to the understanding of the extracellular matrix in the brain and its associated neurological diseases.

2 Aug 2022

in vitro News and Research

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

A broad sarbecovirus-neutralizing antibody cocktail

Scientists explore ex utero generation of post-gastrulation synthetic embryos

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Researchers unravel a novel molecular target of eicosapentaenoic acid

Serbia's genome center monitors potential virus mutations to facilitate more effective COVID-19 control

COVID-19 vaccination increases antibodies in breast milk significantly

Study tests equine polyclonal antibodies against SARS-CoV-2 variants

Inhaled aprotinin found to reduce viral load in mild-to-moderate COVID-19

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

New dual-plasmid editing system for DNA-based information rewriting in vivo

Researchers discover two signaling pathways that are downregulated in human hearts after birth

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

Hemopurifier containing Galanthus nivalis resin removes SARS-CoV-2 variants

Study identifies pivotal role of FIBCD1 gene in neurodevelopmental disorders

Researchers characterize a novel gene likely to cause neurological disorders in humans

Study suggests peimine may be a potent inhibitor of SARS-CoV-2 variant infection

The recent progress in investigating the inhibitory impact of nanosponges and antiviral delivery against SARS-CoV-2

Study indicates that cross-reactive immunity against SARS-CoV-2 N protein was present in Africa prior to the pandemic

What is the role of vitamin D in pandemic H1N1 influenza and SARS-CoV-2 infection?

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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