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Simulating an overactive autoimmune response leads to changes in the brain region

Researchers at the University of Tsukuba in Japan show that simulating an overactive autoimmune response in mice leads to changes in the hippocampal region of the brain.

17 Feb 2021

A new method for controlling leukemic stem cells

Leukemia is caused by leukemic stem cells which are resistant to most known therapies. Relapses are also due to this resistance. Leukemic stem cells arise from normal blood-forming (hematopoietic) stem cells.

17 Feb 2021

Study: Radioactive bone cement is a safer alternative for treating bone tumors

A radioactive bone cement that's injected into bone to provide support and local irradiation is proving to be a safer alternative to conventional radiation therapy for bone tumors, according to a study led by University of California, Irvine researchers.

16 Feb 2021

Biodegradable microcapsules loaded with nerve growth factor can guide neuronal development

Researchers from Skoltech and their colleagues have demonstrated that nanoengineered biodegradable microcapsules can guide the development of hippocampal neurons in an in vitro experiment.

16 Feb 2021

Combining lipid-lowering drugs and lifestyle interventions may yield greatest heart-protecting benefits

Combining healthy lifestyle interventions reduces heart disease through beneficial effects on different lipoproteins and associated cholesterols, according to a study published February 9 in eLife.

16 Feb 2021

Study highlights the epigenetics of life at high altitudes

Humans inhabit an incredible range of environments across the globe, from arid deserts to frozen tundra, tropical rainforests, and some of the highest peaks on Earth.

16 Feb 2021

Maternal cardiovascular health in pregnancy associated with child's heart health in adolescence

A mother's heart health while she is pregnant may have a significant impact on her child's cardiovascular health in early adolescence (ages 10 to 14), according to a new study from Northwestern Medicine and the Ann & Robert H. Lurie Children's Hospital of Chicago.

16 Feb 2021

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

The National Cancer Institute has granted a $2.5 million, five-year R37 MERIT Award to Dr. Bryan Burt, associate professor of surgery and chief of the Division of General Thoracic Surgery, for his research project titled, "Proteomic Determinants of Response to Checkpoint Blockade in Malignant Pleural Mesothelioma."

16 Feb 2021

Kruppel-like factor 15 controls skeletal muscle fat uptake and utilization

Metabolic diseases, such as obesity and type 2 diabetes, have risen to epidemic proportions in the U.S. and occur in about 30 percent of the population. Skeletal muscle plays a prominent role in controlling the body's glucose levels, which is important for the development of metabolic diseases like diabetes.

16 Feb 2021

Discovery opens up the possibility to predict metastases even before cancer develops

The researchers analyzed cells, mouse models, and human patient samples using biochemical, mathematical, and biophysical methods.

16 Feb 2021

What are the changes in the physical phenotype of blood cells in COVID-19?

While primarily a respiratory illness, there are distinctive alterations in the type and number of blood cells in COVID-19. A new study by a team of researchers in Germany describes the nature of these changes.

16 Feb 2021

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

A new preprint research paper posted to the bioRxiv server provides a greater understanding of the aspect of humoral immunity against the virus – the plasma cells that pour out a flood of specific antibodies targeting various epitopes on the pathogen.

16 Feb 2021

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Why do patients who receive antipsychotic medications to manage schizophrenia and bipolar disorder quickly gain weight and develop prediabetes and hyperinsulemia?

15 Feb 2021

Drinking, smoking, and drug use may increase risk of premature heart disease in young people

Recreational drinking, smoking, and drug use is linked to premature heart disease in young people, particularly younger women, finds research published online in the journal Heart.

15 Feb 2021

One-size-fits-all approach to evaluating blood pressure could be detrimental to women’s health

A new study from the Smidt Heart Institute at Cedars-Sinai shows that women have a lower "normal" blood pressure range compared to men. The findings were published today in the peer-reviewed journal Circulation.

15 Feb 2021

UTEP professor's discovery could lead to a way to inhibit overeating

Science is a step closer to a new response to obesity, thanks in part to a study conducted by a team that included Sergio Iñiguez, Ph.D., associate professor of psychology at The University of Texas at El Paso.

15 Feb 2021

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders.

15 Feb 2021

How SARS-CoV-2 enters the central nervous system

The central nervous system (CNS) is highly protected in the human body. Yet, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades the CNS, causing profound clinical complications. How is the CNS involved in a respiratory virus infection?

15 Feb 2021

First wearable device for simultaneous monitoring of cardiovascular signals and biochemical levels

Engineers at the University of California San Diego have developed a soft, stretchy skin patch that can be worn on the neck to continuously track blood pressure and heart rate while measuring the wearer's levels of glucose as well as lactate, alcohol or caffeine.

15 Feb 2021

Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments

By capitalizing on a convergence of chemical, biological and artificial intelligence advances, University of Pittsburgh School of Medicine scientists have developed an unusually fast and efficient method for discovering tiny antibody fragments with big potential for development into therapeutics against deadly diseases.

15 Feb 2021

Blood News and Research

Simulating an overactive autoimmune response leads to changes in the brain region

A new method for controlling leukemic stem cells

Study: Radioactive bone cement is a safer alternative for treating bone tumors

Biodegradable microcapsules loaded with nerve growth factor can guide neuronal development

Combining lipid-lowering drugs and lifestyle interventions may yield greatest heart-protecting benefits

Study highlights the epigenetics of life at high altitudes

Maternal cardiovascular health in pregnancy associated with child's heart health in adolescence

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

Kruppel-like factor 15 controls skeletal muscle fat uptake and utilization

Discovery opens up the possibility to predict metastases even before cancer develops

What are the changes in the physical phenotype of blood cells in COVID-19?

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

Study explains why antipsychotic medications lead to weight gain, promote metabolic syndrome

Drinking, smoking, and drug use may increase risk of premature heart disease in young people

One-size-fits-all approach to evaluating blood pressure could be detrimental to women’s health

UTEP professor's discovery could lead to a way to inhibit overeating

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

How SARS-CoV-2 enters the central nervous system

First wearable device for simultaneous monitoring of cardiovascular signals and biochemical levels

Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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