Laboratory News and Research

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New gene-filtering tool aims to predict disease-causing mutations

Despite their bad reputations, the vast majority of mutations are not harmful. Even in very rare genetic disorders, only one or two genetic variations — out of tens of thousands — is actually the cause of disease. Distinguishing between harmful and harmless mutations has long been a challenge.

13 Jan 2016

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Researchers have identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia – a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer.

12 Jan 2016

Mechanical properties of bone revealed through micro-indentation testing

Unravelling the mechanical properties of bone with micro-indentation testing has significance in both health and disease. At the University Medical Center Hamburg-Eppendorf, Dr. Björn Busse and his research group have advanced their micro-indentation testing technique using an Olympus industrial inspection digital light microscope, as an alternative to electron microscopy. The cutting edge research is described in a new application note from Olympus, available online.

From Evident Corporation - Life Sciences 12 Jan 2016

Credit Value Partners closes $12.0 million DIP credit facility with Health Diagnostic Laboratory

Credit Value Partners, LP, as agent for funds and accounts under its management ("CVP"), a registered investment advisor specializing in corporate debt investments, announced that it closed a $12.0 million revolving DIP credit facility with Health Diagnostic Laboratory, Inc.

12 Jan 2016

Genomics portfolio expanded by Illumina

Illumina, Inc., the global leader in sequencing and array-based technologies, today announced the newest addition to its industry-leading next-generation sequencing (NGS) portfolio with the launch of the MiniSeq Sequencing System.

From Illumina, Inc. 12 Jan 2016

LabCorp to offer Interpace's new ThyraMir microRNA classifier test

Interpace Diagnostics announced today that Laboratory Corporation of America Holdings, the world's leading health care diagnostics company, will begin offering Interpace's new ThyraMir microRNA classifier test.

12 Jan 2016

Laser-induced breakdown spectroscopy emerges as fast, cost-efficient method for biomass analysis

Laser-induced breakdown spectroscopy (LIBS) is emerging as a fast, cost-efficient method for identifying the total amount and specific compounds that comprise the inorganic component of biomass. Accurate and reliable analysis of these minerals, such as aluminum, calcium, iron, and silicon is essential, as this "ash" can cause problems when converting biomass to hydrocarbon biofuels, as described in a study published in Industrial Biotechnology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

12 Jan 2016

Novel drug shows promise against metastatic breast cancer in mouse models

A doctor treating a patient with a potentially fatal metastatic breast tumor would be very pleased to find, after administering a round of treatment, that the primary tumor had undergone a change in character - from aggressive to static, and no longer shedding cells that can colonize distant organs of the body.

12 Jan 2016

Researcher seeks to identify probiotic mixes to treat Clostridium difficile infections

Antibiotics that fight infection can adversely affect the digestive tract and give destructive bacteria a chance to flourish, said assistant professor of veterinary and biomedical sciences Joy Scaria of South Dakota State University. His research seeks to identify probiotic mixes to treat intestinal infections, such as Clostridium difficile.

12 Jan 2016

iCardiac provides industry-wide dataset access to enable broader validation of TQT alternative approach

iCardiac Technologies, Inc., a scientific leader in the conduct of cardiac safety assessments, today announced it is providing industry-wide access to its pivotal dataset as part of an effort announced by the Cardiac Safety Research Consortium to enable broader validation of an alternative approach to the Thorough QT (TQT) study.

12 Jan 2016

Cancer concerns over chromium diet pills

Concerns have been raised over the long-term use of nutritional supplements containing chromium, after an Australian research team found the supplement is partially converted into a carcinogenic form when it enters cells.

12 Jan 2016

UCA researchers create new animal models to study link between diabetes and Alzheimer's disease

In recent time, many epidemiological studies have proved very close links existing between diabetes and Alzheimer´s disease. In fact, it has been stated that diabetes is a significant risk factor for suffering from Alzheimer and vascular dementia, the two main causes of dementia.

12 Jan 2016

Discoveries could lead to development of novel therapies to prevent C. diff infection

Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile ("C. diff") -- the leading cause of hospital-acquired diarrhea in the United States.

12 Jan 2016

Excess folic acid intake causes lowered immune function in aged mice

Previous studies have shown an association between high folic acid intake and a reduction in the immune system defenses needed to fight viral infections and cancer. In a new study in mice published in the Journal of Nutritional Biochemistry, scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University set out to determine if excess folic acid intake caused adverse changes in the immune system.

12 Jan 2016

Researchers use quick screening method to identify, test promising anti-Ebola drugs

A quick screening method has been used for the first time in a standard open laboratory to identify and test promising anti-Ebola drugs. This approach increases the possibility of finding new therapies faster.

12 Jan 2016

Easy aspiration of small volumes of biological liquid waste

VACUSIP is a portable benchtop vacuum aspiration system from INTEGRA that you can place wherever you need it. Besides increased mobility, the battery version of the VACUSIP allows you to keep the workspace clean and organized, making it ideal for the use in a Class II safety cabinet.

From INTEGRA Biosciences 11 Jan 2016

Sage Analytics establishes distribution network in South America

Sage Analytics, the developers of portable, laboratory-quality cannabis potency measurement systems, announced it established a distribution network in South America, anchored by Senses Biotech in Uruguay.

11 Jan 2016

Researchers describe three cleaning procedures that effectively remove, disassemble α-Syn fibrils

Lewy bodies and Lewy neurites are found in the brains of Parkinson's disease (PD) patients. They consist primarily of fibrils of the protein alpha-synuclein (α-Syn), which self-assembles into fibrils in vitro. If introduced into the human body, these seeds can act as prions and trigger the formation of toxic protein deposits. Because α-Syn fibrils are often used in research, it is important that they are not accidentally transferred to humans or cell cultures.

11 Jan 2016

NIST chemist develops portable kit for recovering traces of chemical evidence

A chemist at the National Institute of Standards and Technology has developed a portable version of his method for recovering trace chemicals such as environmental pollutants and forensic evidence including secret graves and arson fire debris.

11 Jan 2016

Research could lead to new treatment for Rett Syndrome, other forms of autism

Penn State scientists have discovered a novel drug target and have rescued functional deficits in human nerve cells derived from patients with Rett Syndrome, a severe form of autism-spectrum disorder.

11 Jan 2016

Laboratory News and Research

New gene-filtering tool aims to predict disease-causing mutations

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Mechanical properties of bone revealed through micro-indentation testing

Credit Value Partners closes $12.0 million DIP credit facility with Health Diagnostic Laboratory

Genomics portfolio expanded by Illumina

LabCorp to offer Interpace's new ThyraMir microRNA classifier test

Laser-induced breakdown spectroscopy emerges as fast, cost-efficient method for biomass analysis

Novel drug shows promise against metastatic breast cancer in mouse models

Researcher seeks to identify probiotic mixes to treat Clostridium difficile infections

iCardiac provides industry-wide dataset access to enable broader validation of TQT alternative approach

Cancer concerns over chromium diet pills

UCA researchers create new animal models to study link between diabetes and Alzheimer's disease

Discoveries could lead to development of novel therapies to prevent C. diff infection

Excess folic acid intake causes lowered immune function in aged mice

Researchers use quick screening method to identify, test promising anti-Ebola drugs

Easy aspiration of small volumes of biological liquid waste

Sage Analytics establishes distribution network in South America

Researchers describe three cleaning procedures that effectively remove, disassemble α-Syn fibrils

NIST chemist develops portable kit for recovering traces of chemical evidence

Research could lead to new treatment for Rett Syndrome, other forms of autism

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