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Study uncovers link between T cell-mediated inflammation and cardiac dysfunction

Inflammation is supposed to help protect us - it's part of an immune response to fight off pathogens and clear infections. But patients with cardiac disease often have chronic inflammation that damages their hearts, even with no infection present.

5 Feb 2021

Fecal transplant overcomes resistance to immunotherapy in melanoma patients

Researchers at UPMC Hillman Cancer Center and the National Cancer Institute demonstrate that changing the gut microbiome can transform patients with advanced melanoma who never responded to immunotherapy - which has a failure rate of 40% for this type of cancer - into patients who do.

5 Feb 2021

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

A healthy person has a general balance of good and bad bacteria. But that balance is thrown off when someone gets sick.

5 Feb 2021

Study may lead to new therapeutic strategies to reduce allergic responses, inflammatory reactions

In order to fight pathogens, mast cells regulate inflammatory reactions of the immune system. Both mast cells and neutrophils are white blood cells and are critical for the body's immune defense.

5 Feb 2021

SHREK proteins mediate broad spectrum antiviral host immunity, including against SARS-CoV-2

A new preprint posted to the bioRxiv server demonstrates that similar mucins and mucin-like proteins cannot only suppress HIV-1 infectivity via blockage of viral attachment to the host cells but can block infection by multiple enveloped viruses.

4 Feb 2021

Scripps Research collaborates with Tempus to develop a predictive model of glucose responses

Scripps Research, a globally recognized nonprofit biomedical research institute, today announced a collaborative research program with Tempus, a leader in precision medicine and artificial intelligence, to develop a predictive model of glucose responses in people with and without type 2 diabetes.

4 Feb 2021

Pharmacologist lays out a plan to improve the equity of drug development

In a new perspective piece published in the Feb. 5 issue of Science, pharmacologist Namandje Bumpus, Ph.D. -- who recently became the first African American woman to head a Johns Hopkins University School of Medicine department, and is the only African American woman leading a pharmacology department in the country -- outlines the molecular origins for differences in how well certain drugs work among distinct populations.

4 Feb 2021

Study: Only 14% of the Bernese population developed antibodies against SARS-CoV-2

In the canton of Bern, only 14% of the adult population were infected with the coronavirus and developed antibodies against SARS-CoV-2.

4 Feb 2021

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

A team of scientists from India has recently tested the efficacy and immunogenicity of two different concentrations of a plasmid DNA-based vaccine candidate ZyCoV-D. The findings reveal that the vaccine candidate administered via Needle Free Injection System (NFIS) can significantly induce the production of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein-specific IgG and neutralizing antibodies for a prolonged period.

4 Feb 2021

Novel biomarker may help identify which pancreatic cancer patients respond to CD40 agonists

Inflammation in the blood could serve as a new biomarker to help identify patients with advanced pancreatic cancer who won't respond to the immune-stimulating drugs known as CD40 agonists, suggests a new study from researchers in the Abramson Cancer Center of the University of Pennsylvania published in JCI Insight.

4 Feb 2021

New guidance can help cardiac patients with diabetes to exercise more safely

Cardiac patients who also have diabetes will be able to do their rehabilitation exercises more safely, thanks to the world's first guidance on the subject, which has been published by international experts including a Swansea University academic.

4 Feb 2021

School gardens may get children to eat more vegetables

Getting children to eat their vegetables can seem like an insurmountable task, but nutrition researchers at The University of Texas at Austin have found one way: school gardens and lessons on using what's grown in them.

4 Feb 2021

New study to examine stress, cancer risk and reproductive toxicity in women firefighters

Researchers at the University of Arizona Health Sciences are undertaking a study to better understand the potential enviromental and occupational health risks specific to women in the fire service.

4 Feb 2021

Cancer patients less likely to receive life-saving therapy when suffering a heart attack

A major study of nearly 2 million heart attack patients has found that many who also had cancer were not offered a potentially lifesaving treatment, despite the fact it had major benefits.

4 Feb 2021

Alzheimer's risk gene can increase COVID-19 susceptibility and severity

A City of Hope-led research team found that the same gene that increases the risk for Alzheimer's disease, ApoE4, can increase the susceptibility to and severity of COVID-19.

4 Feb 2021

Gut microbiome can modulate the immune response in liver cancer patients with NAFLD

The distinctive gut microbiome profile of a person with liver cancer linked to non-alcoholic fatty liver disease (NAFLD) could be the key to predicting someone's risk of developing the cancer, say researchers from the UNSW Microbiome Research Centre.

4 Feb 2021

New drug candidate to be trialed for most lethal form of brain cancer

A new drug candidate has been discovered by the University of South Australia to treat the most lethal form of brain cancer - glioblastoma - which kills 95 per cent of patients within five years.

4 Feb 2021

Monoclonal antibodies against SARS-CoV-2 spike's N-terminal prove highly protective in vivo

A new study server reports highly protective neutralizing monoclonal antibodies against the SARS-CoV-2.

4 Feb 2021

Study finds cancer as the leading cause of death among patients with diabetes

Cancer is the leading cause of death among people with diabetes in England. This is the finding of an 18-year-study of over 300,000 people with diabetes in England, from scientists from Imperial College London and published in the journal The Lancet Diabetes & Endocrinology.

4 Feb 2021

Resonance-guided vaporization may provide new ways of treating tumors

Sending tiny droplets to a tumor and having them vaporized using focused ultrasound: it could be a new way of tracing a tumor or deliver drugs locally.

4 Feb 2021

Blood News and Research

Study uncovers link between T cell-mediated inflammation and cardiac dysfunction

Fecal transplant overcomes resistance to immunotherapy in melanoma patients

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

Study may lead to new therapeutic strategies to reduce allergic responses, inflammatory reactions

SHREK proteins mediate broad spectrum antiviral host immunity, including against SARS-CoV-2

Scripps Research collaborates with Tempus to develop a predictive model of glucose responses

Pharmacologist lays out a plan to improve the equity of drug development

Study: Only 14% of the Bernese population developed antibodies against SARS-CoV-2

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

Novel biomarker may help identify which pancreatic cancer patients respond to CD40 agonists

New guidance can help cardiac patients with diabetes to exercise more safely

School gardens may get children to eat more vegetables

New study to examine stress, cancer risk and reproductive toxicity in women firefighters

Cancer patients less likely to receive life-saving therapy when suffering a heart attack

Alzheimer's risk gene can increase COVID-19 susceptibility and severity

Gut microbiome can modulate the immune response in liver cancer patients with NAFLD

New drug candidate to be trialed for most lethal form of brain cancer

Monoclonal antibodies against SARS-CoV-2 spike's N-terminal prove highly protective in vivo

Study finds cancer as the leading cause of death among patients with diabetes

Resonance-guided vaporization may provide new ways of treating tumors

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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