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Study shows that human hormones also follow a seasonal pattern

Our minds may be affected by winter's long nights or spring's flowers, but what about our bodies? A new study at the Weizmann Institute of Science reveals that our hormones also follow a seasonal pattern.

4 Feb 2021

Chronic hypoxia upregulates RNA polymerase I, alters methylation on ribosomal RNAs

Hypoxia -- where a tissue is deprived of an adequate supply of oxygen -- is a feature inside solid cancer tumors that renders them highly invasive and resistant to treatment. Study of how cells adapt to this critical stressor, by altering their metabolism to survive in a low-oxygen environment, is important to better understand tumor growth and spread.

4 Feb 2021

Researchers define key questions to help the UK government for next biosecurity threat

During the summer of 2019, a global team of experts put their heads together to define the key questions facing the UK government when it comes to biological security.

4 Feb 2021

Hematological findings in Amazonian patients with COVID-19

To discriminate between patients with severe and non-severe COVID-19 quickly, researchers from Peru looked for prognostic signatures in the blood samples of COVID-19 patients. Virgilio E. Failoc-Rojas et al. examined laboratory results and clinical prognosis of COVID-19 patients from a hospital in the Peruvian Amazon.

3 Feb 2021

NeuroVision Imaging receives ADDF funding to develop biomarker tests for Alzheimer's disease

NeuroVision Imaging Inc., announced today it has received an investment from the Alzheimer's Drug Discovery Foundation to support developing reliable, affordable biomarker tests for Alzheimer's disease and other forms of dementia and neurodegenerative disorders.

3 Feb 2021

Insight into role of aging in response to SARS-CoV-2 infection

Researchers at the University of California, Irvine set out to determine the differences between young people and older adults regarding their host responses against SARS-CoV-2. The team revealed that independent of disease severity, COVID-19 was linked to a significant shift in plasma inflammatory factors. The research is posted to the pre-print server medRxiv*.

3 Feb 2021

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Pompe disease is a hereditary genetic disorder caused by a deficiency of acid alpha-glucosidase leading to build-up of glycogen in the lyosomes, which then causes cell damage in various tissues, in particular the heart, the muscles, the liver and the nervous system.

3 Feb 2021

Preclinical study uncovers how Zika virus passes from mother to fetus during pregnancy

A preclinical study by a University of South Florida Health Morsani College of Medicine research team has discovered a new mechanism for how Zika virus can pass from mothers to their children during pregnancy - a process known as vertical transmission.

3 Feb 2021

Early use of therapeutic anticoagulation does not improve survival of critically ill COVID-19 patients

Although abnormal blood clotting has been identified as one of the primary causes of death from COVID-19, early treatment in an intensive care unit (ICU) with therapeutic anticoagulation (anti-clotting) for adults who are critically ill with COVID-19 does not appear to improve chances of survival, and could do more harm than good by increasing the risk for major bleeding, a multicenter research group cautions.

3 Feb 2021

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

A phase 1 clinical trial testing a novel vaccine approach to prevent HIV has produced promising results, IAVI and Scripps Research announced today.

3 Feb 2021

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

A study by Mayo Clinic researchers published in Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells.

3 Feb 2021

Extreme blood sugar swings in patients with type 2 diabetes linked to high risk of heart disease

In patients with type 2 diabetes, big swings in blood sugar levels between doctors' visits are associated with an increased risk of heart disease.

3 Feb 2021

Two studies describe processes that affect the generation of new fat cells

Gaining more fat cells is probably not what most people want, although that might be exactly what they need to fight off diabetes and other diseases.

3 Feb 2021

Scalp cooling physically protects hair follicles from chemotherapy drugs, research shows

Ground-breaking research from the University of Huddersfield, announced ahead of World Cancer Day 2021, proves that scalp cooling physically protects hair follicles from chemotherapy drugs.

3 Feb 2021

Study finds higher pediatric SARS-CoV-2 burden than previously reported in the U.S.

In a new study, published on the pre-print server medRxiv*, researchers at Inova Children's Hospital and the George Mason University revealed that a much higher burden of SARS-CoV-2 infection was found in children than previously reported. This comes after the researchers assessed seropositivity among 1,038 children and adolescents.

3 Feb 2021

Researchers report trial results of rectal microbicides at HIV R4P Virtual Conference

Researchers seeking to develop on-demand and behaviorally congruent HIV prevention options for people who practice anal sex are reporting the results of three early phase clinical trials of rectal microbicides at this week's HIV Research for Prevention (HIV R4P) Virtual Conference.

3 Feb 2021

Study examines motivations and barriers to convalescent plasma donation in the UK

Researchers have given new insights into why people would choose to donate Covid-19 plasma after recovering from the virus, which will be used to support the recruitment of convalescent plasma donors to help treat current Covid-19 patients and support ongoing trials.

3 Feb 2021

Blood News and Research

Study shows that human hormones also follow a seasonal pattern

Chronic hypoxia upregulates RNA polymerase I, alters methylation on ribosomal RNAs

Researchers define key questions to help the UK government for next biosecurity threat

Hematological findings in Amazonian patients with COVID-19

NeuroVision Imaging receives ADDF funding to develop biomarker tests for Alzheimer's disease

Insight into role of aging in response to SARS-CoV-2 infection

Spark Therapeutics launches gene therapy clinical trial for late-onset Pompe disease

Preclinical study uncovers how Zika virus passes from mother to fetus during pregnancy

Early use of therapeutic anticoagulation does not improve survival of critically ill COVID-19 patients

Phase 1 clinical trial of novel HIV vaccine approach shows promising results

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

Extreme blood sugar swings in patients with type 2 diabetes linked to high risk of heart disease

Two studies describe processes that affect the generation of new fat cells

Scalp cooling physically protects hair follicles from chemotherapy drugs, research shows

Study finds higher pediatric SARS-CoV-2 burden than previously reported in the U.S.

Researchers report trial results of rectal microbicides at HIV R4P Virtual Conference

Study examines motivations and barriers to convalescent plasma donation in the UK

Study: Brain hormones could improve metabolism and fight obesity

Comprehensive study on prenatal causes of kidney disease in adults

New technology uses near-infrared imaging and machine learning to find hidden tumors

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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