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SARS-CoV-2 may join the ranks of mild cold-causing coronaviruses

What is the endgame for SARS-CoV-2, the virus that is causing worldwide devastation? If it becomes endemic -- circulating in the general population -- and most people are exposed in childhood, SARS-CoV-2 may join the ranks of mild cold-causing coronaviruses that currently circulate in humans, according to a model developed by Emory and Penn State scientists.

13 Jan 2021

Medical institutions should support health care workers with COVID-19 infection, say experts

By mid-November, the Centers for Disease Control and Prevention had reported that 218,439 health care workers in the U.S. had been infected with COVID-19 -- a likely underestimate due to incomplete data from states.

13 Jan 2021

Researchers develop novel antibody fragments against SARS coronavirus-2

An international research team led by the University of Bonn (Germany) has identified and further developed novel antibody fragments against the SARS coronavirus-2. These "nanobodies" are much smaller than the classic antibodies used to treat US President Donald Trump, for example.

13 Jan 2021

Study shows how neurons can become a target of SARS-CoV-2 infection

Using both mouse and human brain tissue, researchers at Yale School of Medicine have discovered that SARS-CoV-2 can directly infect the central nervous system and have begun to unravel some of the virus's effects on brain cells.

13 Jan 2021

Cardiovascular deaths unrelated to COVID-19 increased during the pandemic, study finds

As the number of COVID-19 infections continues to rise nationwide, more than 360,000 Americans have already died from the potentially deadly viral infection.

13 Jan 2021

New clinical practice guidelines on diagnosis, management of von Willebrand Disease

The American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), National Hemophilia Foundation (NHF), and World Federation of Hemophilia (WFH) have developed joint clinical practice guidelines on the diagnosis and management of von Willebrand Disease (VWD), the world's most common inherited bleeding disorder. The guidelines were published today in Blood Advances.

13 Jan 2021

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Reprogramming the rich connective tissue microenvironment of a liver cancer known as intrahepatic cholangiocarcinoma (ICC) inhibits its progression and resistance to standard chemotherapy in animal models, researchers from Massachusetts General Hospital have found.

12 Jan 2021

Scientists determine ideal dose of stem cells to control HIV

Scientists have determined the optimal conditions following a stem cell transplant that could control HIV without the need of an everyday pill, according to a study published today in eLife.

12 Jan 2021

Poor gut health may adversely affect COVID-19 prognosis

People infected with COVID-19 experience a wide range of symptoms and severities, the most commonly reported including high fevers and respiratory problems.

12 Jan 2021

Metabolites may be predictive indicators of patients at risk for recurrent major depression

Researchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites - small molecules produced by the process of metabolism - may be predictive indicators for persons at risk for recurrent major depressive disorder.

12 Jan 2021

Rotten egg gas may help protect aging brain cells from Alzheimer’s disease

Typically characterized as poisonous, corrosive and smelling of rotten eggs, hydrogen sulfide's reputation may soon get a face-lift thanks to Johns Hopkins Medicine researchers.

12 Jan 2021

California budget reflects ‘pandemic-induced reality,’ governor says

The coronavirus pandemic doomed Gov. Gavin Newsom's ambitious plans last year to combat homelessness, expand behavioral health services and create a state agency to control soaring health care costs.

12 Jan 2021

Will the Pfizer–BioNTech vaccine be effective against the new N501Y SARS-CoV-2 variant?

Researchers from Pfizer and the University of Texas, USA, have presented evidence showing that people in a previously reported trial of the mRNA-based COVID-19 vaccine, BNT162b2 – commonly known as the Pfizer-BioNTech COVID-19 vaccine – had equivalent neutralizing titers to the N501 and Y501 viruses.

12 Jan 2021

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed insulin nanoparticles that may one day become the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.

12 Jan 2021

Study shows COVID-19 pneumonia is different from typical pneumonia

Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung over the course of hours. In the modern intensive care unit, these bacteria or viruses are usually controlled either by antibiotics or by the body's immune system within the first few days of the illness.

12 Jan 2021

Researchers develop new technique to more efficiently isolate and identify rare T cells

Scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a technique that will enable researchers to more efficiently isolate and identify rare T cells that are capable of targeting viruses, cancer and other diseases.

12 Jan 2021

Stress during pregnancy could affect the baby's chance of developing multiple diseases

Stress on an expectant mother could affect her baby's chance of developing disease - perhaps even over the course of the child's life, UC researchers have found.

12 Jan 2021

Patient with hypertension or cardiovascular diseases experienced critical disease progression with COVID-19

COVID-19 patients who also suffer from high blood pressure are more likely to fall severely ill with the disease, which also leaves them at greater risk of death.

11 Jan 2021

Mosaic mutations during embryonic development can cause autism spectrum disorder

Two studies in today's Nature Neuroscience, led by researchers at Boston Children's Hospital, Brigham and Women's Hospital (BWH), and Harvard Medical School (HMS), implicate mosaic mutations arising during embryonic development as a cause of autism spectrum disorder (ASD). The findings open new areas for exploring the genetics of ASD and could eventually inform diagnostic testing.

11 Jan 2021

Extract of medicinal plant Artemisia annua interferes with replication of SARS-CoV-2 in vitro

Researchers in the United States have shown that extracts of an aromatic herb called Artemisia annua inhibit the replication of severe acute respiratory coronavirus (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

11 Jan 2021

Blood News and Research

SARS-CoV-2 may join the ranks of mild cold-causing coronaviruses

Medical institutions should support health care workers with COVID-19 infection, say experts

Researchers develop novel antibody fragments against SARS coronavirus-2

Study shows how neurons can become a target of SARS-CoV-2 infection

Cardiovascular deaths unrelated to COVID-19 increased during the pandemic, study finds

New clinical practice guidelines on diagnosis, management of von Willebrand Disease

Researchers discover a new approach to inhibit intrahepatic cholangiocarcinoma

Scientists determine ideal dose of stem cells to control HIV

Poor gut health may adversely affect COVID-19 prognosis

Metabolites may be predictive indicators of patients at risk for recurrent major depression

Rotten egg gas may help protect aging brain cells from Alzheimer’s disease

California budget reflects ‘pandemic-induced reality,’ governor says

Will the Pfizer–BioNTech vaccine be effective against the new N501Y SARS-CoV-2 variant?

Insulin nanoparticles may become an alternative to insulin injections for diabetic patients

Study shows COVID-19 pneumonia is different from typical pneumonia

Researchers develop new technique to more efficiently isolate and identify rare T cells

Stress during pregnancy could affect the baby's chance of developing multiple diseases

Patient with hypertension or cardiovascular diseases experienced critical disease progression with COVID-19

Mosaic mutations during embryonic development can cause autism spectrum disorder

Extract of medicinal plant Artemisia annua interferes with replication of SARS-CoV-2 in vitro

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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