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Jersey Shore to break ground on HOPE Tower to provide new healing outpatient experience for the community

Jersey Shore University Medical Center, part of the Meridian Health family, is preparing to break ground this fall on the HOPE Tower Project - a $265 million dollar building development on the hospital's east campus that will provide a new healing outpatient experience for the community. HOPE Tower's expected date of completion is early 2018.

1 Sep 2015

After acute myocardial infarction, respiratory infection associated with increased risk of mortality

Respiratory infection is associated with a four-fold increased risk of in-hospital cardiovascular mortality after acute myocardial infarction (AMI), according to research presented at ESC Congress today by Dr Catarina Quina-Rodrigues, a cardiologist at Hospital de Braga in Portugal. The findings highlight the importance of diagnostic alertness for respiratory infections in AMI patients so that therapeutic measures can be promptly taken.

31 Aug 2015

Cholinergic neurons in basal forebrain broadcast message throughout the cerebral cortex

When a large combat unit, widely dispersed in dense jungle, goes to battle, no single soldier knows precisely how his actions are affecting the unit's success or failure. But in modern armies, every soldier is connected via an audio link that can instantly receive broadcasts - reporting both positive and negative surprises - based on new intelligence. The real-time broadcasts enable dispersed troops to learn from these reports and can be critical since no solider has an overview of the entire unit's situation.

28 Aug 2015

New study may lead to effective treatment to prevent common chemotherapy side effects in cancer patients

Annually, hundreds of thousands of patients battling cancer undergo chemotherapy, which often results in poorly tolerated side effects such as nausea, vomiting, and loss of the desire to eat.

28 Aug 2015

Findings reveal a new way to prevent meningitis

The fungus Cryptococcus causes meningitis, a brain disease that kills about 1 million people each year — mainly those with impaired immune systems due to AIDS, cancer treatment or an organ transplant.

28 Aug 2015

Proportion of diabetes patients undergoing coronary artery bypass grafting rises from 7% to 37% in 40 years

In the 40 years between 1970-2010, the proportion of patients with diabetes undergoing coronary artery bypass grafting (CABG) escalated from 7% to 37%. The results of a large study from Cleveland Clinic just published in The Journal of Thoracic and Cardiovascular Surgery, the official publication of the American Association for Thoracic Surgery, documents the five-fold increase in the proportion of patients with diabetes undergoing this procedure between 1970 and 2010.

28 Aug 2015

Researchers identify drugs that may enhance ability of TKI dasatinib to kill human cancer cells

Researchers have discovered how a common mutation in a high-risk leukemia subtype drives the cancer's aggressiveness and have identified drugs that may work with existing precision medicines to improve survival. St. Jude Children's Research Hospital scientists led the study, which was published online today in the journal Cancer Cell.

28 Aug 2015

ieCrowd announces achievement of major milestone in commercial development of Smart Oxygen device

ieCrowd today announced the achievement of an important milestone in the commercial development of the company's supplemental oxygen delivery device, Smart Oxygen. The Smart Oxygen device, being developed by ieCrowd's subsidiary Smart Oxygen Solutions, automatically adjusts to a patient's changing demand for oxygen based on level of activity.

28 Aug 2015

Researchers identify druggable target to potentially root out colon cancer, end relapse

Researchers targeting colorectal cancer stem cells - the root cause of disease, resistance to treatment and relapse - have discovered a mechanism to mimic a virus and potentially trigger an immune response to fight the cancer like an infection.

28 Aug 2015

Adaptive immune system plays active role in guiding development of mammary glands

In experiments with mouse tissue, UC San Francisco researchers have discovered that the adaptive immune system, generally associated with fighting bacterial and viral infections, plays an active role in guiding the normal development of mammary glands, the only organs--in female humans as well as mice--that develop predominately after birth, beginning at puberty.

28 Aug 2015

Children exposed to toxic air pollutants at home more likely to have lower GPAs

A University of Texas at El Paso study on children's health has found that fourth and fifth graders who are exposed to toxic air pollutants at home are more likely to have lower GPAs.

28 Aug 2015

Discovery could open up door for cancer research and treatment

Florida State University researchers have taken a big step forward in the fight against cancer with a discovery that could open up the door for new research and treatment options.

28 Aug 2015

Brainbow technique reveals surprising data about brain's visual circuitry

Neuroscientists know that some connections in the brain are pruned through neural development. Function gives rise to structure, according to the textbooks. But scientists at the Virginia Tech Carilion Research Institute have discovered that the textbooks might be wrong.

28 Aug 2015

Researchers find way to trigger 'virus alert' that may help boost drug's ability to prevent cancer cells

Working with human cancer cell lines and mice, researchers at the Johns Hopkins Kimmel Cancer Center and elsewhere have found a way to trigger a type of immune system "virus alert" that may one day boost cancer patients' response to immunotherapy drugs. An increasingly promising focus of cancer research, the drugs are designed to disarm cancer cells' ability to avoid detection and destruction by the immune system.

27 Aug 2015

Health providers still prescribing expensive malaria drugs in Nigeria to patients who do not have malaria

Health providers trained to perform malaria rapid diagnostic tests (RDT) are still prescribing valuable malaria medicines to patients who do not have malaria, according to new research published in PLOS ONE.

27 Aug 2015

Study sheds further light on the way APOL1 protein kills trypanosmoe

The African trypanosome Trypanosoma brucei is a blood parasite capable of infecting many mammals. Humans are provided with natural immunity against infection through the activity of the protein apolipoprotein L1 (APOL1): captured via endocytosis, APOL1 forms pores in the lysosomal membrane, leading to the death of the trypanosome.

27 Aug 2015

New ORNL interface can identify, characterize solid or liquid sample

In mere seconds, a system developed at the Department of Energy's Oak Ridge National Laboratory can identify and characterize a solid or liquid sample, providing a valuable tool with applications in material science, forensics, pharmaceuticals, biology and chemistry.

27 Aug 2015

Transplanting multi-layered sheet of liver cells into damaged liver improves function in test animals

Liver transplantation is currently the only established treatment for patients with end stage liver failure. However, this treatment is limited by the shortage of donors and the conditional integrity and suitability of the available organs. Transplanting donor hepatocytes (liver cells) into the liver as an alternative to liver transplantation also has drawbacks as the rate of survival of primary hepatocytes is limited and often severe complications can result from the transplantation procedure.

27 Aug 2015

New study describes multi-method strategy to improve detection of PMS2 gene mutations in Lynch syndrome

About 3% of colorectal cancers are due to Lynch syndrome, an inherited cancer susceptibility syndrome that predisposes individuals to various cancers. Close blood relatives of patients with Lynch syndrome have a 50% chance of inheritance. The role that PMS2 genetic mutations play in Lynch syndrome has been underestimated in part due to technological limitations.

27 Aug 2015

Researchers design online database to help researchers identify cancer gene mutations

Many clinical trials use genome sequencing to learn which gene mutations are present in a patient's tumor cells. The question is important because targeting the right mutations with the right drugs can stop cancer in its tracks. But it can be difficult to determine whether there is evidence in the medical literature that particular mutations might drive cancer growth and could be targeted by therapy, and which mutations are of no consequence.

27 Aug 2015

Laboratory News and Research

Jersey Shore to break ground on HOPE Tower to provide new healing outpatient experience for the community

After acute myocardial infarction, respiratory infection associated with increased risk of mortality

Cholinergic neurons in basal forebrain broadcast message throughout the cerebral cortex

New study may lead to effective treatment to prevent common chemotherapy side effects in cancer patients

Findings reveal a new way to prevent meningitis

Proportion of diabetes patients undergoing coronary artery bypass grafting rises from 7% to 37% in 40 years

Researchers identify drugs that may enhance ability of TKI dasatinib to kill human cancer cells

ieCrowd announces achievement of major milestone in commercial development of Smart Oxygen device

Researchers identify druggable target to potentially root out colon cancer, end relapse

Adaptive immune system plays active role in guiding development of mammary glands

Children exposed to toxic air pollutants at home more likely to have lower GPAs

Discovery could open up door for cancer research and treatment

Brainbow technique reveals surprising data about brain's visual circuitry

Researchers find way to trigger 'virus alert' that may help boost drug's ability to prevent cancer cells

Health providers still prescribing expensive malaria drugs in Nigeria to patients who do not have malaria

Study sheds further light on the way APOL1 protein kills trypanosmoe

New ORNL interface can identify, characterize solid or liquid sample

Transplanting multi-layered sheet of liver cells into damaged liver improves function in test animals

New study describes multi-method strategy to improve detection of PMS2 gene mutations in Lynch syndrome

Researchers design online database to help researchers identify cancer gene mutations

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