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Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

In a recent study published in the journal Science Immunology, researchers in the United States described a rare anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) three antibody cocktail IMM-BCP-01.

4 Jul 2022

The role of vitamin D in H1N1 influenza and SARS-CoV-2 infection

A new study focused on determining Vitamin D's role in SARS-CoV-2 and H1N1 influenza. In this study, researchers determined the effect of vitamin D supplements on the lung anti-viral response in animal models.

4 Jul 2022

Study provides better understanding of how therapeutic resistance develops in lung cancer

New Cleveland Clinic research has uncovered key information about cellular interaction between tumor cells and normal tissue, providing better understanding of how therapeutic resistance develops.

1 Jul 2022

New antibody-based method for SARS-CoV-2 detection does not require a blood sample

Despite significant and stunning advances in vaccine technology, the COVID-19 global pandemic is not over. A key challenge in limiting the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is identifying infected individuals.

1 Jul 2022

The antiviral effects of thiol drugs in COVID-19

A recent study investigated the effects of thiol drugs on SARS-CoV-2.

1 Jul 2022

Combining AI and Zebrafish to Accelerate Drug Discovery

As part of our SLAS Europe 2022 coverage, we speak to Dr. Javier Terriente, Co-founder and Chief of Drug Development at ZeClinics, about how zebrafish could be the future for discovering new therapeutics.

From Society for Laboratory Automation and Screening (SLAS) 1 Jul 2022

SARS-CoV-2 3CLpro also susceptible to mutations

Researchers assess the activity of all potential mutations in the SARS-CoV-2 3CLpro.

29 Jun 2022

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Researchers investigated the epigenetic rewiring of odor perception in SARS-CoV-2-infected cells.

29 Jun 2022

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

IgA and IgG in human breast milk and blood were assessed for their activity against SARS-CoV-2 and SARS-CoV-1, as well as four other prevalent HCoVs.

28 Jun 2022

Effectiveness of monoclonal antibodies and directly acting antivirals against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages

Researchers assessed the in vivo effectiveness of monoclonal antibodies and directly acting antiviral agents against the SARS-CoV-2 Omicron BA.1 and BA.2 sublineages.

28 Jun 2022

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

A recent study posted to the bioRxiv* preprint server assessed whether niclosamide could be employed in coronavirus disease 2019 (COVID-19) therapy.

28 Jun 2022

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

In a recent article posted to the bioRxiv* preprint server, researchers at Texas Biomedical Research Institute, Georgia State University, and the University of Alabama at Birmingham developed a bireporter-expressing recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) for tracking SARS-CoV-2 infection.

27 Jun 2022

Researchers discover a molecular switch that promotes pancreatic cancer metastasis

More than 62,000 people in the United States will be diagnosed with pancreatic cancer by the end of this year, with the vast majority having a deadly and aggressive subtype known as pancreatic ductal adenocarcinoma (PDA).

27 Jun 2022

Lipid-peptide nanocomplexes offer new mRNA platform

A new paper reports the methodical development of lipid-peptide nanocomplexes as a delivery vehicle for messenger ribonucleic acid molecules to the tumor cell, in vitro and in vivo.

27 Jun 2022

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

It has become abundantly clear that coronavirus disease 19 (COVID-19), despite being transmitted by breathing in the SARS-CoV-2 virus, can have harmful effects far beyond the lungs.

27 Jun 2022

Study investigates the virological attributes of Omicron in a Syrian hamster model

Researchers investigated the virological attributes of SARS‐CoV‐2 new variant of concern Omicron in a Syrian hamster model.

27 Jun 2022

Genetic screening results just got harder to handle under new abortion rules

Ann was 15 weeks pregnant with her fourth child when the results of her prenatal genetic test came back last August.

27 Jun 2022

Mice study unravels the role of T. denticola in Alzheimer's disease pathogenesis

Tau hyperphosphorylation is the key characteristic pathological hallmarks of Alzheimer's disease (AD). Recently studies showed periodontitis and periodontal pathogen are significant risk factors for AD.

26 Jun 2022

Five things to know now that the Supreme Court has overturned Roe V. Wade

The Supreme Court's decision in Dobbs v. Jackson Health dramatically and rapidly alters the landscape of abortion access in the U.S.

24 Jun 2022

KHN’s ‘What the Health?’: Supreme Court overturns ‘Roe’

The Supreme Court formally overturned the nearly 50-year-old right to abortion. Bolstered by the three justices appointed by former President Donald Trump, the 6-3 vote wiped from the books the two cases that had established and reaffirmed abortion rights; 1973's Roe v. Wade and 1992's Planned Parenthood of Southeastern Pennsylvania v. Casey.

24 Jun 2022

in vitro News and Research

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

The role of vitamin D in H1N1 influenza and SARS-CoV-2 infection

Study provides better understanding of how therapeutic resistance develops in lung cancer

New antibody-based method for SARS-CoV-2 detection does not require a blood sample

The antiviral effects of thiol drugs in COVID-19

Combining AI and Zebrafish to Accelerate Drug Discovery

SARS-CoV-2 3CLpro also susceptible to mutations

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

Effectiveness of monoclonal antibodies and directly acting antivirals against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

Researchers discover a molecular switch that promotes pancreatic cancer metastasis

Lipid-peptide nanocomplexes offer new mRNA platform

COVID-19 can cause metabolism problems by interfering with insulin signaling, study reveals

Study investigates the virological attributes of Omicron in a Syrian hamster model

Genetic screening results just got harder to handle under new abortion rules

Mice study unravels the role of T. denticola in Alzheimer's disease pathogenesis

Five things to know now that the Supreme Court has overturned Roe V. Wade

KHN’s ‘What the Health?’: Supreme Court overturns ‘Roe’

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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