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New technique for vaccine design could prove useful against HIV, other viral strains

A team led by scientists from The Scripps Research Institute (TSRI) and the International AIDS Vaccine Initiative (IAVI) has unveiled a new technique for vaccine design that could be particularly useful against HIV and other fast-changing viruses.

30 Mar 2013

Weekend reading: Seniors smoking marijuana; Same-sex marriage and public health

For Cher Neufer, a 65-year-old retired teacher, socializing with friends (all in their 60s) means using marijuana. Once a week they get together to play Texas Hold 'Em poker "and pass around a doobie," Ms. Neufer said. … Statistics suggest that more members of the older generations, like Ms. Neufer, are using marijuana.

30 Mar 2013

New research shows how metabolism and physiology are connected to diet

Sometimes you just can't resist a tiny piece of chocolate cake. Even the most health-conscious eaters find themselves indulging in junk foods from time to time. New research by scientists at the University of Massachusetts Medical School raises the striking possibility that even small amounts of these occasional indulgences may produce significant changes in gene expression that could negatively impact physiology and health.

30 Mar 2013

Medicare reimbursement cuts threaten access to care

Physicians and patients alike are feeling the impact of Medicare reimbursement cuts that went into effect on January 1, 2013. With an additional 2% sequestration cut to roll out on April 1, it's likely that physicians who treat Medicare patients will be faced with difficult decisions as operating margins continue to shrink.

29 Mar 2013

Research shows immune system can destroy HIV through deactivation of vif gene

Human cells have an intrinsic capacity to destroy HIV. However, the virus has evolved to contain a gene that blocks this ability. When this gene is removed from the virus, the innate human immune system destroys HIV by mutating it to the point where it can no longer survive.

29 Mar 2013

Study: Protein clumps in nerve cells are pathologies of Parkinson's disease

Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.

29 Mar 2013

Different metrics should be used in different settings to measure ARV program success

Studies show "the profound impact of antiretroviral-therapy coverage at a population level" -- how wider coverage can increase life expectancy and reduce the risk of HIV infection.

29 Mar 2013

TSRI scientists receive innovative grant to help people break nicotine addiction

As part of an unprecedented national effort to develop new drugs to treat neurological disorders, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded an innovative grant from the National Institute of Neurological Disorders and Stroke to help people break their addiction to nicotine.

28 Mar 2013

New screening procedure determines animal, plant, and microbial substances in foodstuffs

Scientists at the Institute of Molecular Genetics, Genetic Security Research and Consulting at Johannes Gutenberg University Mainz (JGU) have developed a novel screening procedure that provides for highly sensitive, quantifiable analysis of animal, plant, and microbial substances present in foodstuffs.

28 Mar 2013

University of Maryland scientist selected as fellow of newly created AACR Academy

Angela H. Brodie, Ph.D., a University of Maryland scientist whose research paved the way for a new class of drugs widely used to treat breast cancer patients around the world, has been selected by the American Association for Cancer Research as a fellow of the newly created AACR Academy.

28 Mar 2013

Johns Hopkins scientists identify DNA-damaging substances in food

In a laboratory study pairing food chemistry and cancer biology, scientists at the Johns Hopkins Kimmel Cancer Center tested the potentially harmful effect of foods and flavorings on the DNA of cells.

28 Mar 2013

TSRI scientists awarded innovative grant to develop anti-smoking drug candidates

As part of an unprecedented national effort to develop new drugs to treat neurological disorders, scientists from the Florida campus of The Scripps Research Institute have been awarded an innovative grant from the National Institute of Neurological Disorders and Stroke to help people break their addiction to nicotine.

28 Mar 2013

New laboratory study shows certain protein particles multiply, spread from one cell to another

In diseases like Alzheimer's and Parkinson's endogenous proteins accumulate in the brain, eventually leading to the death of nerve cells. These deposits, which consist of abnormally formed proteins, are supposed to migrate between interconnected areas of the brain, thereby contributing to the development of the illness.

28 Mar 2013

Study links genetic variation, wheezing illness to childhood asthma risk

About 90 percent of children with two copies of a common genetic variation and who wheezed when they caught a cold early in life went on to develop asthma by age 6, according to a study to be published March 28 by the New England Journal of Medicine.

28 Mar 2013

New research sheds light on natural mechanism that protects ears from hearing loss

New research from the Massachusetts Eye and Ear, Harvard Medical School and Harvard Program in Speech and Hearing Bioscience and Technology may have discovered a key piece in the puzzle of how hearing works by identifying the role of the olivocochlear efferent system in protecting ears from hearing loss.

28 Mar 2013

Researchers reprogramming skin cells into brain cells to understand Alzheimer's disease

Sam Gandy, MD, PhD, of the Icahn School of Medicine at Mount Sinai is leading an international team of researchers working to reprogram skin cells into brain cells to gain a better understanding of Alzheimer's disease.

28 Mar 2013

Royal Holloway University supports Muscular Dystrophy Campaign

Royal Holloway University, is today giving money generated by its research into Duchenne muscular dystrophy to the Muscular Dystrophy Campaign.

27 Mar 2013

Research paper highlights implementation of infectious disease curriculum in Boston Public Schools

A research paper published online this month in Academic Medicine highlights the successful development, implementation, and effects of an infectious disease curriculum that has now been piloted in five Boston Public Schools.

27 Mar 2013

CHOP researchers moving closer to personalized medicine for children with cancer

Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments.

27 Mar 2013

Penn researchers develop nanotechnology-inspired technique for diagnosing Lyme disease

Early diagnosis is critical in treating Lyme disease. However, nearly one quarter of Lyme disease patients are initially misdiagnosed because currently available serological tests have poor sensitivity and specificity during the early stages of infection.

27 Mar 2013

Laboratory News and Research

New technique for vaccine design could prove useful against HIV, other viral strains

Weekend reading: Seniors smoking marijuana; Same-sex marriage and public health

New research shows how metabolism and physiology are connected to diet

Medicare reimbursement cuts threaten access to care

Research shows immune system can destroy HIV through deactivation of vif gene

Study: Protein clumps in nerve cells are pathologies of Parkinson's disease

Different metrics should be used in different settings to measure ARV program success

TSRI scientists receive innovative grant to help people break nicotine addiction

New screening procedure determines animal, plant, and microbial substances in foodstuffs

University of Maryland scientist selected as fellow of newly created AACR Academy

Johns Hopkins scientists identify DNA-damaging substances in food

TSRI scientists awarded innovative grant to develop anti-smoking drug candidates

New laboratory study shows certain protein particles multiply, spread from one cell to another

Study links genetic variation, wheezing illness to childhood asthma risk

New research sheds light on natural mechanism that protects ears from hearing loss

Researchers reprogramming skin cells into brain cells to understand Alzheimer's disease

Royal Holloway University supports Muscular Dystrophy Campaign

Research paper highlights implementation of infectious disease curriculum in Boston Public Schools

CHOP researchers moving closer to personalized medicine for children with cancer

Penn researchers develop nanotechnology-inspired technique for diagnosing Lyme disease

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