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Scientists develop high-throughput strategy to build de novo genomes

Scientists from the Icahn School of Medicine at Mount Sinai have developed a new approach to build nearly complete genomes by combining high-throughput DNA sequencing with genome mapping. The methodology enabled researchers to detect complex forms of genomic variation, critically important for their association with human disease, but previously difficult to detect.

30 Jun 2015

Present-day efforts to cut mercury emissions may reduce pollution more quickly than current models

A Dartmouth-led study using a 600-year-old ice core shows that global mercury pollution increased dramatically during the 20th century, but that mercury concentrations in the atmosphere decreased faster than previously thought beginning in the late 1970s when emissions started to decline.

30 Jun 2015

Study could point the way to new treatments for people with severe asthma

The immune response that occurs in patients with severe asthma is markedly different than what occurs in milder forms of the lung condition, according to researchers from the University of Pittsburgh School of Medicine. Those unique features could point the way to new treatments, they said in an article published online today in the Journal of Clinical Investigation.

30 Jun 2015

Amphetamine-based drug Evekeo effective in treating ADHD symptoms in children

The amphetamine-based drug Evekeo, given once or twice daily to children 6-12 years of age, is effective in treating attention-deficit/hyperactivity disorder (ADHD) symptoms and improving performance in a laboratory classroom setting, according to the results of a new study published in the Journal of Child and Adolescent Psychopharmacology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Jun 2015

Kay E. Davies named recipient of ASHG's 2015 William Allan Award

The American Society of Human Genetics has named Kay E. Davies, DPhil, Dr. Lee's professor of anatomy, associate head of the medical sciences division; and director of the Medical Research Council Functional Genomics Unit in the department of physiology, anatomy and genetics at the University of Oxford, the 2015 recipient of the annual William Allan Award.

30 Jun 2015

Study may lead to better treatments for children with neuroblastoma

Researchers studying the pediatric cancer neuroblastoma have detailed how cancer-driving mutations evolve during chemotherapy, and they hope to exploit this knowledge to design better treatments for children.

30 Jun 2015

Researchers discover gene locations affecting wrist bones in children

Pediatric researchers have discovered gene locations affecting bone strength in wrist bones, the most common site for fractures in children. Children who have those genetic variants may be at higher-than-average risk of wrist fractures, and could especially benefit from activities and diets that promote bone strength.

30 Jun 2015

Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

Laboratories that test chemicals for neurological toxicity could reduce their use of laboratory mice and rats by replacing these animal models with tiny aquatic flatworms known as freshwater planarians.

29 Jun 2015

Synthetic Biologics announces initiation of SYN-010 Phase 2 clinical trial for treatment of IBS-C

Synthetic Biologics, Inc., a clinical-stage company focused on developing therapeutics to protect the microbiome while targeting pathogen-specific diseases, reported the initiation of a Phase 2 clinical trial of its proprietary SYN-010 for the treatment of irritable bowel syndrome with constipation (IBS-C).

29 Jun 2015

Two physician-scientists in search for better Alzheimer's disease treatment

Two of the nation's leading physician-scientists in the search to better understand and treat Alzheimer's disease - William Mobley, MD, PhD, and Michael Rafii, MD, PhD - have been named interim co-directors of the Alzheimer's Disease Cooperative Study (ADCS), a major initiative formed in 1991 as a cooperative agreement between the National Institute on Aging (NIA) and the University of California, San Diego.

27 Jun 2015

Kenall Manufacturing introduces light fixture to kill harmful bacteria linked to HAIs

Kenall Manufacturing today introduced Indigo-Clean, a light fixture that uses Continuous Environmental Disinfection technology to continuously kill harmful bacteria linked to hospital acquired infections (HAIs). The technology behind Indigo-Clean inactivates a wide range of micro-organisms that are known causes of HAIs, including MRSA (Methicillin-resistant Staphylococcus aureus), C.difficile and VRE (Vancomycin-resistant Enterococcus).

27 Jun 2015

Researchers identify specific calcium channel that plays crucial role in healthy sleep

Sleep seems simple enough, a state of rest and restoration that almost every vertebrate creature must enter regularly in order to survive. But the brain responds differently to stimuli when asleep than when awake, and it is not clear what brain changes happen during sleep.

27 Jun 2015

Bristol-Myers Squibb to establish R&D center in Cambridge Kendall Square innovation cluster

Alexandria Real Estate Equities, Inc., the largest and leading REIT uniquely focused on collaborative science campuses in urban innovation clusters, announced today that Bristol-Myers Squibb, a global biopharmaceutical company, will establish a state-of-the-art research and development center at the Alexandria Center at Kendall Square (ACKS) in the heart of the Cambridge Kendall Square innovation cluster.

27 Jun 2015

SeraCare Life Sciences inks CRADA with NCI to create positive controls for cancer assays

SeraCare Life Sciences, a leading partner to global in vitro diagnostics manufacturers, today announced that it has signed a Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute, part of the National Institutes of Health, to create reference materials and positive controls for cancer assays.

26 Jun 2015

Brain research promises better understanding of schizophrenia, autism spectrum disorders

Our brain recognizes objects within milliseconds, even if it only receives rudimentary visual information. Researchers believe that reliable and fast recognition works because the brain is constantly making predictions about objects in the field of view and is comparing these with incoming information.

26 Jun 2015

CarePoint Health, Shiel Medical Laboratory announce strategic partnership

CarePoint Health, a fully integrated healthcare system that provides quality, patient-focused healthcare to residents of the Hudson County region, and Fresenius North America, through its subsidiary Shiel Medical Laboratory, a reference laboratory offering clinical, anatomic pathology and molecular testing services to the greater New York and New Jersey area, today announced a strategic partnership.

26 Jun 2015

New report on global market for point of care diagnostics

The market for point of care diagnostics reached $17 billion, in 2014, according to Kalorama Information. The term refers to diagnostic tests performed outside the central laboratory or decentralized.

26 Jun 2015

IPs spend more time in collecting and reporting hospital infection data than protecting patients

Collecting and reporting hospital infection data to federal health agencies takes more than 5 hours each day, at the expense of time needed to ensure that frontline healthcare personnel are adhering to basic infection prevention practices such as hand hygiene, according to a recent case study, to be presented on Saturday, June 27 at the 42nd Annual Conference of the Association for Professionals in Infection Control and Epidemiology.

26 Jun 2015

New Christian Doppler Laboratory for Complement Research opens at MedUni Vienna

Today the new Christian Doppler Laboratory for Complement Research was opened at the Center for Pathophysiology, Infectiology and Immunology at MedUni Vienna. The research institute, which is funded by the Federal Ministry of Science, Research and Economic Affairs (BMWFW) is concentrating on a special protein that is thought to play an important role in controlling excessive immune reactions.

26 Jun 2015

New strategies may help clinicians and hospitals better manage patients with chronic conditions

Experts have identified strategies for using electronic health records to improve care for patients with chronic kidney disease. The guidance, which will appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), may help clinicians and hospitals better manage individual patients with chronic conditions and identify groups of patients most likely to benefit from different treatment strategies.

26 Jun 2015

Laboratory News and Research

Scientists develop high-throughput strategy to build de novo genomes

Present-day efforts to cut mercury emissions may reduce pollution more quickly than current models

Study could point the way to new treatments for people with severe asthma

Amphetamine-based drug Evekeo effective in treating ADHD symptoms in children

Kay E. Davies named recipient of ASHG's 2015 William Allan Award

Study may lead to better treatments for children with neuroblastoma

Researchers discover gene locations affecting wrist bones in children

Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

Synthetic Biologics announces initiation of SYN-010 Phase 2 clinical trial for treatment of IBS-C

Two physician-scientists in search for better Alzheimer's disease treatment

Kenall Manufacturing introduces light fixture to kill harmful bacteria linked to HAIs

Researchers identify specific calcium channel that plays crucial role in healthy sleep

Bristol-Myers Squibb to establish R&D center in Cambridge Kendall Square innovation cluster

SeraCare Life Sciences inks CRADA with NCI to create positive controls for cancer assays

Brain research promises better understanding of schizophrenia, autism spectrum disorders

CarePoint Health, Shiel Medical Laboratory announce strategic partnership

New report on global market for point of care diagnostics

IPs spend more time in collecting and reporting hospital infection data than protecting patients

New Christian Doppler Laboratory for Complement Research opens at MedUni Vienna

New strategies may help clinicians and hospitals better manage patients with chronic conditions

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