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Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

Researchers model a complex childhood disease on-a-chip

Millions of children in low- and middle-income nations suffer from environmental enteric dysfunction (EED), a chronic inflammatory disease of the intestine that is the second leading cause of death in children under five years old.

23 Jun 2022

Kratom: A dangerous or beneficial plant?

A new study summarizes the traditional and modern uses of kratom, as well as its pharmacology, benefits, and adverse health impacts.

23 Jun 2022

Midgestation increase in leptin puts child and mother at risk of cardiovascular disease

Before a baby is ever born, critical supply chain problems with nutrition and oxygen can result in premature birth or even death and increase the child and mother's lifelong risk of cardiovascular disease.

23 Jun 2022

Research assesses ability of SARS‐CoV‐2‐neutralising mAbs to prevent COVID‐19

In a recent study published in the Cochrane Library, researchers searched multiple databases to identify randomized controlled trials (RCTs) that evaluated severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐neutralizing monoclonal antibodies (mAbs).

23 Jun 2022

SARS-CoV-2 evades natural killer cell cytotoxic responses

In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.

22 Jun 2022

The possible immune-mediated mechanisms causing CNS alterations during and post-acute SARS-CoV-2 infection

In a recent review published in Immunity, researchers explored potential mechanisms of neuro-immune pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

22 Jun 2022

Researchers map cancer driver mutations across the human genome

In a recent study published in Nature Biotechnology, researchers explored the causes of cancer by mapping somatic mutation rates across the human genome.

22 Jun 2022

Potential SARS-CoV-2 antivirals based on host miRNAs

A recent research paper posted to the bioRxiv* preprint server demonstrated micro ribonucleic acids (miRNAs) as potential antiviral options against various coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

21 Jun 2022

Wistar scientists discover a new way to boost a person's immune response to tumors

Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.

21 Jun 2022

Study finds traditional African drug inhibits growth of SARS-CoV-2 infection

Researchers evaluated the efficacy of PHELA, a traditional African drug, against SARS-CoV-2 in vitro.

21 Jun 2022

Researchers assess monkeypox clinical management guidelines worldwide

A new study demonstrated the scarcity of appropriate clinical management guidelines for monkeypox infections across the globe.

20 Jun 2022

The feasibility of sperm cryopreservation for male COVID-19 patients

In an article recently published in Frontiers in Endocrinology, scientists deciphered the possibility of cryopreserving sperm of coronavirus disease 2019 (COVID-19) patients

20 Jun 2022

Nanoparticles may be the next-generation solution for teeth whitening

Researchers reviewed nanoparticles (NPs) as next-generation whitening agents for teeth.

17 Jun 2022

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Researchers assessed the impact of SARS-CoV-2-neutralizing antibodies on the SARS-CoV-2 Omicron variant.

17 Jun 2022

GPR183 gene a novel drug target for severe COVID-19

In a recent study posted to the bioRxiv* pre-print server, researchers provide the first preclinical evidence of the usefulness of antagonists of G-protein coupled receptor 183 (GPR183), also known as Epstein-Barr virus-induced gene 2 (EBI2), in reducing coronavirus disease 2019 (COVID-19) severity.

17 Jun 2022

First-of-its-kind technology repairs and regenerates heart muscle cells

Researchers at the University of Houston are reporting a first-of-its-kind technology that not only repairs heart muscle cells in mice but also regenerates them following a heart attack, or myocardial infarction as its medically known.

16 Jun 2022

Researchers evaluate artemisinin for COVID-19 management

Researchers assessed the effectiveness of artemisinin-based antimalarials in the management of COVID-19.

16 Jun 2022

Fc-effector functions for selecting COVID-19 convalescent plasma

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that coronavirus disease 2019 (COVID-19) convalescent plasmas (CCPs) with low neutralizing and high fragment crystallizable (Fc)-effector activity result in effective prophylaxis.

15 Jun 2022

Two broadly neutralizing antibodies show promise to provide long-acting immunity against SARS-CoV-2

Two broadly neutralizing antibodies show great promise to provide long-acting immunity against COVID-19 in immunocompromised populations according to a paper published June 15 in the Journal of Experimental Medicine (JEM).

15 Jun 2022