Laboratory News and Research

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Nucleoporin proteins play significant role in maintaining embryonic stem cells

What if you found out that pieces of your front door were occasionally flying off the door frame to carry out chores around the house? That's the kind of surprise scientists at the Salk Institute experienced with their recent discovery that nucleoporins -- proteins that act as cellular 'doorways' to help manage what goes in and out of a cell's nucleus -- are actually much bigger players in expressing genes than previously thought.

19 Jun 2015

Study demonstrates potential of new approach for sorting out BRCA1 gene variants

Patients seeking certainty in genetic tests often receive a perplexing result. Many learn they carry a 'variant of unknown significance' of a disease-linked gene. Such variants might -- or equally might not -- increase disease risk.

19 Jun 2015

NIH researchers develop 'placenta-on-a-chip' to study role of placenta in pregnancy

National Institutes of Health researchers and their colleagues have developed a "placenta-on-a-chip" to study the inner workings of the human placenta and its role in pregnancy. The device was designed to imitate, on a micro-level, the structure and function of the placenta and model the transfer of nutrients from mother to fetus. This prototype is one of the latest in a series of organ-on-a-chip technologies developed to accelerate biomedical advances.

18 Jun 2015

Key lessons from Middle East Respiratory Syndrome outbreak in South Korea

The outbreak of Middle East Respiratory Syndrome (MERS) in South Korea is the subject of a fast-tracked editorial in the International Journal of Infectious Diseases, written by Dr. Eskild Petersen and colleagues.

18 Jun 2015

Public health experts outline strategies for managing MERS-CoV outbreak

The ongoing outbreak in the Republic of Korea (South Korea) is an important reminder that the Middle East respiratory virus (MERS-CoV) requires constant vigilance and could spread to other countries including the United States. However, MERS can be brought under control with effective public health strategies, say two Georgetown University public health experts.

18 Jun 2015

New study launched in Liberia to better understand health consequences of Ebola virus disease

The Liberia-U.S. clinical research partnership known as PREVAIL has launched a study of people in Liberia who have survived Ebola virus disease (EVD) within the past two years. The study investigators hope to better understand the long-term health consequences of EVD, determine if survivors develop immunity that will protect them from future Ebola infection, and assess whether previously EVD-infected individuals can transmit infection to close contacts and sexual partners.

18 Jun 2015

NIH-funded study identifies DOCK2 deficiency

Researchers funded by the National Institutes of Health have identified a new immune disorder--DOCK2 deficiency--named after the mutated gene responsible for the disease.

18 Jun 2015

Scientists explain the existence of intrinsic chirality in ordinary nanocrystals

A team of scientists from ITMO University and Trinity College Dublin published first experimental results showing that ordinary nanocrystals possess intrinsic chirality and can be produced under normal conditions as a half-and-half mixture of mirror images of each other.

18 Jun 2015

Beckman Coulter brings new thinking to new lab challenges at EuroMedLab 2015

Beckman Coulter Diagnostics supports IFCC-EFLM EuroMedLab 2015 with a showcase of solutions to improve workflow for the diagnostics laboratory. Held from 22-24 June 2015 at the Paris Palais des Congrès France, the company demonstrates its dedication to moving the clinical diagnostic lab forward with its total laboratory solution—from automation, chemistry, immunoassay and haematology to microbiology and its new molecular diagnostics system.

From Beckman Coulter Diagnostics 18 Jun 2015

New tissue 'scaffold' technology could one day help produce large organs

Scientists have developed a new tissue 'scaffold' technology that could one day enable the engineering of large organs. Research led by the Universities of Bristol and Liverpool has shown that it is possible to combine cells with a special scaffold to produce living tissue in the laboratory. It is hoped this can then be implanted into patients as a way of replacing diseased parts of the body.

17 Jun 2015

ALK1 protein determines the extent of breast tumour's spread in the body

For breast cancer to be fatal, the tumour has to send out metastases to other parts of the body. The cancer cells are spread via the blood vessels, and a research team at Lund University in Sweden has now proven that the protein ALK1 determines the extent of the tumour's spread in the body.

17 Jun 2015

TGen, Phoenix Children's Hospital developing new methods to store and transport blood samples

The Translational Genomics Research Institute and Phoenix Children's Hospital are developing new economical methods of preserving, storing and transporting high-quality blood plasma proteins for use in diagnosing and treating disease.

17 Jun 2015

New DARPA grant supports Wyss Institute project that aims to fight gastrointestinal illness

For decades, American travelers to international destinations have been plagued by acute gastrointestinal illnesses that can arise from travel to other countries. The Center for Disease Control warns that depending on the destination, between 30 to 70 percent of travelers can expect to experience gastrointestinal distress from ingesting foreign or pathogenic bacteria that can be present in poorly sanitized water or food.

17 Jun 2015

TSRI chemists invent scalable method for synthesizing brain-protecting compound

Chemists at The Scripps Research Institute have invented the first practical, scalable method for synthesizing jiadifenolide, a plant-derived molecule that may have powerful brain-protecting properties.

17 Jun 2015

Bayer HealthCare, Johns Hopkins University to jointly develop new ophthalmic therapies targeting retinal diseases

The Johns Hopkins University and Bayer HealthCare have entered into a five-year collaboration agreement to jointly develop new ophthalmic therapies targeting retinal diseases. The goal of the strategic research alliance is to accelerate the translation of innovative approaches from the laboratory to the clinic, ultimately offering patients new treatment options for several retinal diseases.

17 Jun 2015

ImmunArray to launch SLE-key Rule Out test for lupus in select U.S. markets

At the premier European forum on rheumatologic disorders, ImmunArray, maker of a breakthrough technology that provides unprecedented levels of accuracy in ruling out the presence of lupus through a simple blood test, announced today that it is launching its new SLE-key™ Rule Out test in selected U.S. markets on July 1, 2015.

17 Jun 2015

Fruit flies helping FAU researchers to discover novel genes responsible for neuroprotection

They're pesky and annoying when they get into your fruit, but Drosophila melanogaster, more affectionately known as the "fruit fly," are helping researchers at Florida Atlantic University to discover novel genes that are responsible for neuroprotection.

17 Jun 2015

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

CQDM and Ontario Centres of Excellence will fund five highly innovative and unconventional game-changing research and development projects to accelerate drug discovery in the Quebec-Ontario Life Sciences Corridor. Partners are granting $1.5M to Quebec-based and, for the first time, Ontario-based researchers thanks to the partnership with OCE through CQDM's 2014 Explore Program, one of CQDM's flagship programs focusing on early concept validation of cutting-edge technologies that address the most crucial needs in drug discovery and development.

17 Jun 2015

Althea obtains European GMP certificate from HPRA for commercial aseptic filling and testing

Ajinomoto Althea, Inc., a leading provider of biopharmaceutical contract development and manufacturing services announced today that it has officially received its European GMP certificate from the Health Products Regulatory Authority for commercial aseptic filling and testing.

16 Jun 2015

Stony Brook University, CadheRx Therapeutics sign licensing agreement for anti-cancer technology

Stony Brook University has entered into a licensing agreement with a startup company, CadheRx Therapeutics, to develop and market an anti-cancer technology discovered by Sabine Brouxhon, MD, Clinical Associate Professor in the Department of Emergency Medicine at Stony Brook University School of Medicine.

16 Jun 2015

Laboratory News and Research

Nucleoporin proteins play significant role in maintaining embryonic stem cells

Study demonstrates potential of new approach for sorting out BRCA1 gene variants

NIH researchers develop 'placenta-on-a-chip' to study role of placenta in pregnancy

Key lessons from Middle East Respiratory Syndrome outbreak in South Korea

Public health experts outline strategies for managing MERS-CoV outbreak

New study launched in Liberia to better understand health consequences of Ebola virus disease

NIH-funded study identifies DOCK2 deficiency

Scientists explain the existence of intrinsic chirality in ordinary nanocrystals

Beckman Coulter brings new thinking to new lab challenges at EuroMedLab 2015

New tissue 'scaffold' technology could one day help produce large organs

ALK1 protein determines the extent of breast tumour's spread in the body

TGen, Phoenix Children's Hospital developing new methods to store and transport blood samples

New DARPA grant supports Wyss Institute project that aims to fight gastrointestinal illness

TSRI chemists invent scalable method for synthesizing brain-protecting compound

Bayer HealthCare, Johns Hopkins University to jointly develop new ophthalmic therapies targeting retinal diseases

ImmunArray to launch SLE-key Rule Out test for lupus in select U.S. markets

Fruit flies helping FAU researchers to discover novel genes responsible for neuroprotection

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

Althea obtains European GMP certificate from HPRA for commercial aseptic filling and testing

Stony Brook University, CadheRx Therapeutics sign licensing agreement for anti-cancer technology

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