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Phase 2 clinical trial results of IMO-2055 announced

Idera Pharmaceuticals, Inc., today announced the presentation of final data from a clinical trial evaluating IMO-2055, an agonist of Toll-like Receptor (TLR) 9, as monotherapy in patients with Renal Cell Carcinoma (RCC). The data are being presented during the Eighth International Kidney Cancer Symposium being held in Chicago, September 25-26, 2009.

28 Sep 2009

FDA grants accelerated approval for Allos Therapeutics’ FOLOTYN

Allos Therapeutics, Inc. (Nasdaq:ALTH) today announced that last night the U.S. Food and Drug Administration (FDA) granted accelerated approval for FOLOTYNTM (pralatrexate injection) for use as a single agent for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).

28 Sep 2009

NSERC awards $5M grant to develop faster detection methods for cancer

A nanomedicine research group led by a University of Toronto chemist has received a $5-million grant from the Natural Sciences and Engineering Research Council of Canada (NSERC), giving them the green light to develop faster ways of detecting leukemia and lung cancer cells.

28 Sep 2009

Pelosi tries to unite divided Democratic factions in House

Speaker Nancy Pelosi, D-Calif., is facing a difficult task in the House: herding the different Democratic factions to fashion a single health care bill.

28 Sep 2009

Improving the accuracy of violent behaviour prediction may alleviate negative effects of violence

In the future, diagnosing severe personality disorders, evaluating the childhood environment, assessing alcohol consumption and the analysis of the MAOA genotype may provide more accurate means for assessing risk among violent offenders, according to the Finnish research carried out jointly at the University of Helsinki and the Helsinki University Central Hospital Psychiatry Centre.

28 Sep 2009

Quintiles opens an expanded regional facility

To enhance service offerings throughout Europe, Quintiles Transnational Corp. today announced the opening of an expanded regional facility near Edinburgh, Scotland. The purpose-built facility consolidates three buildings into a single state-of-the-art complex.

28 Sep 2009

Physicians should implement new measures while diagnosing prenatal Down syndrome

New prenatal tests for Down syndrome are soon to be offered to all pregnant women across the United States, yet telling an expectant couple that their child will be born with Down syndrome is a task very few physicians are trained for, claims research published in the American Journal of Medical Genetics.

28 Sep 2009

WHO Asia-Pacific Countries pledge to use artemisinin with other drugs by 2015 to prevent drug-resistance

On Wednesday, nine of the 10 countries in the WHO's Asia-Pacific region "that suffer most" from malaria pledged to phase out the use of artemisinin-only to treat malaria and use it in combination with other drugs by 2015, Reuters reports (Lyn, 9/23).

28 Sep 2009

Universal bilirubin screening can reduce jaundice incidence in newborns

Screening all newborns for excessive bilirubin in the blood can significantly decrease the incidence of severe jaundice which, in extreme cases, can lead to seizures and brain damage, according to researchers at UCSF Children's Hospital and Kaiser Permanente's Division of Research in Oakland, CA.

28 Sep 2009

$Diabetic patients face increased risk of bone fractures$

Diabetic patients face increased risk of bone fractures

Current research suggests that the inflammatory molecule TNF-α may contribute to delayed bone fracture healing in diabetics. The related report by Alblowi et al, "High Levels of TNF-α Contribute to Accelerated Loss of Cartilage in Diabetic Fracture Healing" appears in the October 2009 issue of the American Journal of Pathology.

28 Sep 2009

Research reveals prophylactic mastectomy is on the rise

A new study of New York State data finds that the number of women opting for surgery to remove the healthy breast after a cancer diagnosis in one breast is rising, despite a lack of evidence that the surgery can improve survival.

28 Sep 2009

Progress on the Baucus Bill is in the eye of the beholder

The New York Times: "Senate Democrats on Friday preserved the guts of their proposal to reinvent the health care system, but Republicans scored political points on several issues, like the effects of the bill on older Americans. The Democrats beat back Republican attacks on the legislation as the Senate Finance Committee deferred some of the most contentious issues to next week."

28 Sep 2009

Fresh from G-20, Obama renews health care push

President Barack Obama on Saturday resumed his push to overhaul the health care system, telling a Congressional Black Caucus conference that there comes a time when 'the cup of endurance runs over.

28 Sep 2009

Neuroscience and sports scientists collaborate to help atheletes

Bioscientists and sports scientists are meeting this week to discuss the application of bioscience research to help investigate challenges presented by the UK high performance sport community.

28 Sep 2009

Investigational vaccine regimen 31% effective in preventing HIV infection

In an encouraging development, an investigational vaccine regimen has been shown to be well-tolerated and to have a modest effect in preventing HIV infection in a clinical trial involving more than 16,000 adult participants in Thailand. Following a final analysis of the trial data, the Surgeon General of the U.S. Army, the trial sponsor, announced today that the prime-boost investigational vaccine regimen was safe and 31 percent effective in preventing HIV infection.

27 Sep 2009

Rosiglitazone slows progression of cachexia in cancer affected mice

Insulin resistance, the hallmark of type 2 diabetes and a condition often associated with obesity, is paradoxically also an apparent contributor to muscle wasting and severe fat loss that accompanies some cancers, according to new research.

27 Sep 2009

INFORMS annual meeting in San Diego from October 11th to 14th

When 4,000 experts in everything from problems with California's hospitals to a perpetual game of Monopoly come to San Diego on October 11, the city will find itself deluged not only by smart people who use math for a living but also problem solvers who tackle America's greatest threats.

26 Sep 2009

Network in Canada to develop biomaterials for treatment of eye diseases

Researchers in Canada have established a new university/industry network to pursue the development of biomaterials, medical devices and drug delivery systems to treat the increasing incidence of eye disease.

26 Sep 2009

Contagious diseases more prevalent due to presenteeism

While employers may celebrate a low absenteeism rate among their employees, there may be a more serious problem if sick employees are coming to work. "Presenteeism," a new term coined for when employees work while unhealthy, may be even worse for employers and for the healthcare system, costing $160 billion annually in lost productivity, according to healthcare market research firm Kalorama Information, in its new report "The Market for Wellness Programs and Their Impact on Pharmaceutical, Diagnostic and Device Product Markets." The report also notes that presenteeism costs are one of many factors driving usage of wellness programs.

26 Sep 2009

Biden emerges as health care messenger

The vice president took the stage Wednesday for the administration's health reform campaign with a talk with seniors at Leisure World in suburban Maryland. The Associated Press reports: "Vice President Joe Biden sought to reassure nervous seniors Wednesday that they won't see cuts in their Medicare benefits if the nation's health care system is revamped. ...

26 Sep 2009