Laboratory News and Research

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Researchers explore evolution of eardrums

Researchers at the RIKEN Evolutionary Morphology Laboratory and the University of Tokyo in Japan have determined that the eardrum evolved independently in mammals and diapsids--the taxonomic group that includes reptiles and birds. Published in Nature Communications, the work shows that the mammalian eardrum depends on lower jaw formation, while that of diapsids develops from the upper jaw.

22 Apr 2015

Columbia University School of Nursing receives $6.5 million to educate future nurse leaders

Columbia University School of Nursing has been awarded a $6.5 million grant from the Helene Fuld Health Trust for three vital projects that will educate future nurse leaders.

22 Apr 2015

Scientists use computer simulations to study how evolution makes invaders spread even faster

Today, invasive animals and plants spread all around the globe. Predicting the dynamics of these invasions is of great ecological and socioeconomical interest. Yet studying them is fundamentally challenging because of the large spatial and temporal scales involved. Scientists at Eawag and University of Zurich are now using computer simulations and small artificial laboratory worlds, to study how rapid evolution makes invaders spread even faster.

22 Apr 2015

Botanical formula improves effect of tamoxifen drug in ER+ human breast cancer

Researchers at the Cancer Research Laboratory, Methodist Research Institute, Indiana University Health found that a botanical formula for breast health inhibited the growth of estrogen receptor-positive (ER+) human breast cancer cells. More importantly, the researchers also found that the formula enhanced the anti-cancer benefits of the drug tamoxifen in the treatment of breast cancer.

22 Apr 2015

Discovery unveils novel drug targets to halt peripheral neuropathies, neurodegenerative disorders

New research highlights how nerves - whether harmed by disease or traumatic injury - start to die, a discovery that unveils novel targets for developing drugs to slow or halt peripheral neuropathies and devastating neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS).

22 Apr 2015

Honokiol extract holds promise as adjunct treatment for bladder and kidney cancers

The botanical extract honokiol, a biologically active molecule isolated from the bark of Magnolia spp., holds promise as an adjunct treatment for aggressive bladder and kidney cancers, as reported in two new studies. New research on honokiol in bladder cancer was presented at the American Association for Cancer Research Annual Meeting 2015.

22 Apr 2015

Tumor necrosis factor helps regulate sensitivity to bitter taste

New research from the Monell Center reveals that tumor necrosis factor (TNF), an immune system regulatory protein that promotes inflammation, also helps regulate sensitivity to bitter taste. The finding may provide a mechanism to explain the taste system abnormalities and decreased food intake that can be associated with infections, autoimmune disorders, and chronic inflammatory diseases.

22 Apr 2015

Scientists identify protein that could help tame severe inflammation

Researchers have identified a protein that offers a new focus for developing targeted therapies to tame the severe inflammation associated with multiple sclerosis (MS), colitis and other autoimmune disorders.

22 Apr 2015

Female liver cells become more susceptible to adverse effects of drugs, study finds

Female liver cells, and in particular those in menopaused women, are more susceptible to adverse effects of drugs than their male counterparts, according to new research carried out by the JRC. It is well known that women are more vulnerable when it comes to drug-induced liver effects, but it's the first time it has been shown that there are differences at cellular level.

22 Apr 2015

BMC pathologists develop protocols for processing, preserving forensic evidence

Boston Medical Center pathologists have developed a set of protocols for processing and preserving forensic evidence, such as shrapnel, bullets and other projectiles, in surgical specimens (i.e. amputated limbs, injured organs, etc.) after a terrorist attack based on lessons learned from the Boston Marathon bombing.

22 Apr 2015

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

Individuals with type 2 diabetes, who are resistant to insulin, have an excess blood glucose level, which they are now trying to reduce using a new class of diabetes drugs known as the gliflozins.

22 Apr 2015

U of T studies find harmful vehicle emissions spreading farther than thought across Canadian cities

A trio of recently published studies from a team of University of Toronto engineers has found that air pollution could be spreading up to three times farther than thought--contributing to varying levels of air quality across cities.

22 Apr 2015

UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

UC Davis Assistant Professor Mark Huising is a recipient of The Hartwell Foundation 2014 Individual Biomedical Research Award to support his early-stage research toward a cure for juvenile diabetes. Diabetes affects 10 percent of the entire United States population, including approximately a million children. Remarkably, 40 children every day receive the diagnosis of diabetes.

22 Apr 2015

Novel genetic datashare initiative launched to improve detection of inherited breast and ovarian cancers

Quest Diagnostics, the world’s leading provider of diagnostic information services, and Inserm, the French National Institute of Health and Medical Research institution, today launched BRCA Share, a novel datashare initiative they co-founded to provide scientists and laboratory organizations around the world with open access to BRCA1 and BRCA2 genetic data.

From Quest Diagnostics 22 Apr 2015

GenVec, Laboratory of Malaria Immunology and Vaccinology sign research collaboration agreement

GenVec, Inc. today announced that it has signed a research collaboration agreement with the Laboratory of Malaria Immunology and Vaccinology of the National Institute of Allergy and Infectious Diseases, National Institutes of Health.

21 Apr 2015

Bio-Rad grants Beckman Coulter exclusive distribution rights for access HIV and Hepatitis C assays

Bio-Rad is extending its agreement with Beckman Coulter and has named the company exclusive global distributor of Bio-Rad’s Access HIV combo assay and the Access hepatitis C virus (HCV) assay in select geographies...

From Beckman Coulter Diagnostics 21 Apr 2015

Study explores artemisinin resistance in Plasmodium falciparum malaria

According to the World Health Organization's 2014 World Malaria Report, there are an estimated 198 million cases of malaria worldwide with 3.3 billion people at risk for contracting the infection. Although the impact of malaria is still significant, the statistics reflect a considerable reduction in the global malaria burden. Since 2010, disease transmission has been reduced by 30 percent and mortality due to malaria has decreased by almost half.

21 Apr 2015

Lab-on-paper technique could help detect low quality antimalarial drugs

Access to high-quality medicine is a basic human right, but over four billion people live in countries where many medications are substandard or fake. Marya Lieberman of the Department of Chemistry and Biochemistry at the University of Notre Dame and Abigail Weaver a postdoctoral associate in the University's Department of Civil Engineering and Environmental and Earth Sciences took up the challenge of how people in developing countries could detect low quality antimalarial drugs without expensive equipment and without handling dangerous chemicals.

21 Apr 2015

Study opens door to new treatment for hard-to-treat asthmatic children

Researchers have identified a biological basis for asthmatic children who do not respond well to corticosteroid treatment – currently the most effective treatment for chronic asthma and acute asthma attack.

21 Apr 2015

New collaboration brings comprehensive genomic profiling to UC Davis

The UC Davis Comprehensive Cancer Center and the Department of Pathology and Laboratory Medicine have entered into a collaboration with Foundation Medicine, a leading molecular information company. The collaboration brings comprehensive genomic profiling into standard of care at UC Davis, allowing physicians to prescribe the most effective, targeted cancer treatments to patients based on the genomic information specific to each individual's cancer.

21 Apr 2015

Laboratory News and Research

Researchers explore evolution of eardrums

Columbia University School of Nursing receives $6.5 million to educate future nurse leaders

Scientists use computer simulations to study how evolution makes invaders spread even faster

Botanical formula improves effect of tamoxifen drug in ER+ human breast cancer

Discovery unveils novel drug targets to halt peripheral neuropathies, neurodegenerative disorders

Honokiol extract holds promise as adjunct treatment for bladder and kidney cancers

Tumor necrosis factor helps regulate sensitivity to bitter taste

Scientists identify protein that could help tame severe inflammation

Female liver cells become more susceptible to adverse effects of drugs, study finds

BMC pathologists develop protocols for processing, preserving forensic evidence

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

U of T studies find harmful vehicle emissions spreading farther than thought across Canadian cities

UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

Novel genetic datashare initiative launched to improve detection of inherited breast and ovarian cancers

GenVec, Laboratory of Malaria Immunology and Vaccinology sign research collaboration agreement

Bio-Rad grants Beckman Coulter exclusive distribution rights for access HIV and Hepatitis C assays

Study explores artemisinin resistance in Plasmodium falciparum malaria

Lab-on-paper technique could help detect low quality antimalarial drugs

Study opens door to new treatment for hard-to-treat asthmatic children

New collaboration brings comprehensive genomic profiling to UC Davis

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