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Study on mitochondria function

For such crucial biological actors, much remains unknown about exactly how mitochondria function. A new study, published Aug. 12 in the online journal PLoS One, sheds light on mitochondrial biology. Using genetic engineering, researchers interrupted the activity of individual genes directly involved in the production of energy within mitochondria. "If we knock down the function of specific system components, what happens?" said study leader Marni J. Falk, M.D., who directs the Mitochondrial-Genetics Disease Clinic at The Children's Hospital of Philadelphia. "Our ultimate goal is to translate the knowledge into targeted therapies, that is, effective ways to intervene. But first we need to understand the underlying disease mechanisms."

25 Sep 2009

Only 40% of parents will get their child vaccinated against H1N1?

The latest C.S. Mott Children's Hospital National Poll on Children's Health finds only 40 percent of parents indicate they will get their children vaccinated against H1N1 flu -- while 54 percent of parents indicate they will get their children vaccinated against seasonal flu. Among parents who do not plan to get their children vaccinated against H1N1 flu, 46 percent indicate they are not worried about their children getting H1N1 flu, while 20 percent believe H1N1 flu is not serious.

25 Sep 2009

Severe plagiocephaly in babies can lead to ear infections

The recommendation to lay babies on their backs to sleep has reduced sudden infant death syndrome (SIDS), but has led to an increased number of infants with a skull deformity called deformational (or positional) plagiocephaly. Now new research suggests that infants with more severe plagiocephaly may have a higher rate of middle ear abnormalities associated with ear infections (otitis media), reports the September issue of The Journal of Craniofacial Surgery. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, and pharmacy.

25 Sep 2009

Multi-modality imaging to identify plaque

Late-breaking results from the PROSPECT clinical trial shed new light on the types of vulnerable plaque that are most likely to cause sudden, unexpected adverse cardiac events, and on the ability to identify them through imaging techniques before they occur.

25 Sep 2009

Contribution of psychological characteristics to weight loss

Being too optimistic could harm weight loss efforts. Research published in BioMed Central's open access journal, BioPsychoSocial Medicine, reveals the psychological characteristics that may contribute to weight loss.

25 Sep 2009

Interim results of a pilot study using BACE cardiac device released

Mardil, Inc. today announced positive interim data from a pilot study investigating the safety and efficacy of its novel cardiac device - BACE (Basal Annuloplasty of the Cardia Externally) -- in treating mitral valve regurgitation. The condition arises when the heart's mitral valve leaks blood backward into the heart, causing a range of severe and debilitating symptoms.

25 Sep 2009

Athera Biotechnologies and ALPCO sign distribution agreement

Athera Biotechnologies AB, an atherosclerosis R&D company developing novel products for treatment and prevention of cardiovascular disease (CVD), and ALPCO, a company providing high quality research immunoassays, announced today that they have signed a distribution agreement.

25 Sep 2009

H1N1 influenza pandemic could present a host of medical ethics issues: JCB

The anticipated onset of a second wave of the H1N1 influenza pandemic could present a host of thorny medical ethics issues best considered well in advance, according to the University of Toronto Joint Centre for Bioethics, which today released nine papers for public discussion.

25 Sep 2009

Researchers find fungi effective for controlling malaria mosquitoes

In areas where malaria mosquitoes have become resistant to chemical pesticides, mosquito-killing fungi can be an effective tool. Fungal spores can effectively infect and kill malaria mosquitoes, even those that are resistant to pesticides.

25 Sep 2009

MediciGlobal launches latest version of ADapt patient recruitment system

CROs and Pharmaceutical companies are speeding the process of study launch and accelerating patient recruitment. Such initiatives involve the adoption of new processes, technologies and organisational structure. One such initiative is MediciGlobal's unique and proprietary web-based system called ADapt, focused on launching patient recruitment programmes faster.

24 Sep 2009

Fear of back pain from care work is predictive of actually developing it

Whether from heaving, twisting, bending or bad lifting postures, it's well known that caring for the sick or elderly can lead to back pain. This often results in time off work or dropping out of caring professions altogether. Now Danish research published in the online open access journal BMC Musculoskeletal Disorders suggests that the fear of getting back pain from care work is predictive of actually developing it.

24 Sep 2009

Trade groups to church groups share evolving views on health reform

Many groups fear, or are fiercely advocating for, provisions in Democratic health care reform proposals. Others are softening their stances on certain parts of the bills. Here's a sampling from today's clippings.

24 Sep 2009

Health reform ads confusing public, news outlets try to dispel the fog

Advertising on the health care debate, more than $100 million of it spent so far, is offering little understanding on the issue as the dueling sides and media look to dispel myths about what's true and what's not.

24 Sep 2009

Democrats woo AARP, seniors to support health reform bills

"Though AARP hasn't endorsed Obama's health care drive, many of its priorities are reflected in Democratic bills, including reducing gaps in Medicare prescription drug coverage and eliminating Medicare patients' costs for preventive care. This has led some Republicans to question AARP's true loyalties" (Fram, 9/23).

24 Sep 2009

Liquidia founder Dr. Joseph DeSimone honoured with the NIH Director’s Pioneer Award

Liquidia Technologies today announced its founder, Dr. Joseph DeSimone, has received the National Institutes of Health (NIH) Director’s Pioneer Award. Pioneer Awards are designed to support individual scientists of exceptional creativity who propose pioneering – and possibly transforming – approaches to major challenges in biomedical and behavioral research.

24 Sep 2009

Axial Biotech's SCOLISCORE AIS Prognostic Test now available in the U.S.

Axial Biotech, Inc., a company personalizing spine care through the development of molecular diagnostics, announced today that its SCOLISCORE(TM) AIS Prognostic Test is now being made available to spine specialists in the United States. SCOLISCORE is a saliva-based genetic test designed to predict the risk of progression of scoliosis, an abnormal lateral curvature of the spine.

24 Sep 2009

Issues in shared decision-making

At the World Congress on Psychosomatic Medicine which opened today in Torino, Tom Sensky, Professor of Psychiatry at the Imperial College in London, raised some very controversial issues as to the participation of patients in medical decision.

24 Sep 2009

Direct RNA sequencing performed using Helicos’ True Single Molecule Sequencing technology

Helicos BioSciences Corporation a life science company focused on innovative genetic analysis technologies, today announced the publication of a landmark study in which Helicos’ True Single Molecule Sequencing (tSMS)™ technology was used to directly sequence individual molecules of RNA. The paper appeared yesterday in the on-line edition of Nature and will appear in an upcoming 2009 print issue of Nature.

24 Sep 2009

CTRC commences patient enrolment in Phase 2 clinical trial of REOLYSIN for metastatic melanoma

Oncolytics Biotech Inc. announced today that the Cancer Therapy Research Center at the University of Texas Health Science Center (CTRC) has started patient enrolment in a U.S. Phase 2 clinical trial using intravenous administration of REOLYSIN(R) in combination with paclitaxel and carboplatin in patients with metastatic melanoma.

24 Sep 2009

William A. Berry & Son acquired by Suffolk Construction Company

Suffolk Construction Company, New England’s largest construction company announced today that they have acquired William A. Berry & Son (Berry), the second largest construction company in the region.

24 Sep 2009