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‘Lefty’ protein pumps the brakes during initial stages of embryo differentiation

A protein known as Lefty pumps the brakes as human embryos begin to differentiate into the bones, soft tissues and organs that make us.

25 Jan 2022

SARS-CoV-2 virus co-opts intrinsic cellular machinery to suppress interferon production

In a recent study posted to the bioRxiv* preprint server, researchers evaluated the mechanism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated inflammatory marker interferon (IFN) repression in hosts.

25 Jan 2022

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

In a new study, researchers assessed the extent and duration of the neutralization of SARS-CoV-2 Omicron variant of concern after the administration of two and three doses of the BNT162b2 mRNA vaccine.

25 Jan 2022

The long-term neurologic consequences of COVID-19

A team of researchers recently provided insights into central nervous system consequences of the coronavirus disease 2019 (COVID-19) in a perspective paper published in the Science journal.

24 Jan 2022

Short- and long-term systemic responses in the golden hamster following SARS-CoV-2 or influenza A virus infection

A group of researchers used the golden hamster as a model system to better understand the long-term impacts of SARS-CoV-2 infection.

24 Jan 2022

Antibody response 18 months after SARS-CoV-2 infection in vaccinated and unvaccinated individuals

A new study assessed the dynamics of IgG titers over 18 months in patients who had recovered from COVID-19 infections during March 2020.

24 Jan 2022

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Researchers have investigated the pathology and inflammatory response to the Delta variant in mice.

24 Jan 2022

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

A new study revealed that the expression of HERV-W envelope protein (ENV) in lymphoid cells from COVID-19 patients correlated with disease outcome making them biomarkers of lymphocyte exhaustion.

24 Jan 2022

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Are there any risk factors that predispose patients to severe COVID-19 outcomes? A recent study published in the medRxiv* preprint server sheds light on this popular question. Using a combination of population genetics to single-cell RNA sequencing, European researchers identified the respiratory epithelial cell-specific ELF5 gene as a potential mediator for severe COVID-19 cases.

24 Jan 2022

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

In a recent study posted to the bioRxiv* preprint server, researchers developed a novel bioinformatic algorithm to predict host cleavage targets of the SARS-CoV-2 3C-like protease (3CLPro).

23 Jan 2022

SARS-CoV-2 prevalence in bivalve mollusks from harvesting areas in Southern Italy

The goal of the current study was to collect data on the prevalence of SARS-CoV-2 in bivalve mollusks harvested in the Campania region using dd RT-PCR for the detection of low levels of virus in mollusk tissues.

21 Jan 2022

PAXLOVID shown to be highly effective against all SARS-CoV-2 variants

A recent study, currently available on bioRxiv* preprint server, shows that a novel protease inhibitor known as nirmatrelvir has potent activity against Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also other variants evaluated in this paper – which supports its potential role in reducing the disease burden from coronavirus disease 2019 (COVID-19).

21 Jan 2022

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Scientists report that they have built a living "minimal cell" with a genome stripped down to its barest essentials – and a computer model of the cell that mirrors its behavior.

20 Jan 2022

Indian study suggests significant decrease in protection from vaccine or natural immunity against Omicron variant

Researchers present evidence for early community transmission of the SARS-CoV-2 Omicron variant in New Delhi, India.

20 Jan 2022

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

In a new study, researchers discuss the role of calcium signaling pathways as targets of inhibition in potential new antiviral therapeutic pathways for SARS-CoV-2.

20 Jan 2022

Females more prone to long-term post-COVID-19 symptoms

In a recent study published in the Journal of Clinical Medicine, researchers described the results of a multi-center study (LONG-COVID-EXP-CM) that investigated sex differences in coronavirus disease 2019 (COVID-19)-related symptoms and long-term post-COVID-19 symptoms in a group of previously hospitalized COVID-19 survivors in a large Spanish population.

19 Jan 2022

SARS-CoV-2 RNA can be detected in exhaled aerosol

In a study published in the open-access journal Influenza and other Respiratory Viruses, researchers investigated if severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be detected in exhaled aerosol samples obtained from coronavirus disease 2019 (COVID-19) patients during many different types of breathing and coughing. They also analyzed how SARS-CoV-2 infection may affect the size and number of exhaled aerosol particles.

19 Jan 2022

Transcription News and Research

‘Lefty’ protein pumps the brakes during initial stages of embryo differentiation

SARS-CoV-2 virus co-opts intrinsic cellular machinery to suppress interferon production

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

The long-term neurologic consequences of COVID-19

Short- and long-term systemic responses in the golden hamster following SARS-CoV-2 or influenza A virus infection

Antibody response 18 months after SARS-CoV-2 infection in vaccinated and unvaccinated individuals

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

Researchers find ELF5 gene a leading candidate behind severe COVID-19

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

SARS-CoV-2 prevalence in bivalve mollusks from harvesting areas in Southern Italy

PAXLOVID shown to be highly effective against all SARS-CoV-2 variants

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Indian study suggests significant decrease in protection from vaccine or natural immunity against Omicron variant

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

Females more prone to long-term post-COVID-19 symptoms

SARS-CoV-2 RNA can be detected in exhaled aerosol

Exploring the interactions between multiple respiratory viruses

Study shows inequalities in addressing post-acute neurological manifestations of COVID-19

Exploring biological characteristics of SARS-CoV-2-induced myocardial damage

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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