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Protein unfolding key to understanding blood clot mechanics

Fibrin, the chief ingredient of blood clots, is a remarkably versatile polymer. On one hand, it forms a network of fibers -- a blood clot -- that stems the loss of blood at an injury site while remaining pliable and flexible. On the other hand, fibrin provides a scaffold for thrombi, clots that block blood vessels and cause tissue damage, leading to myocardial infarction, ischemic stroke, and other cardiovascular diseases. How does fibrin manage to be so strong and yet so extensible under the stresses of healing and blood flow?

6 Aug 2009

Obama to drug industry: We still have a deal

"Pressed by industry lobbyists, White House officials on Wednesday assured drug makers that the administration stood by a behind-the-scenes deal to block any Congressional effort to extract cost savings from them beyond an agreed-upon $80 billion," The New York Times reports.

6 Aug 2009

Distinctive gene expression in brains of relapsing heroin-addicted rats

A group of genes whose expression is significantly altered following exposure to drug paraphernalia after an enforced 'cold-turkey' period have been identified. Researchers writing in the open access journal BMC Neuroscience studied gene expression in the brains of heroin-addicted rats, identifying those genes that may be involved in precipitating a relapse.

6 Aug 2009

Insurance industry speaks up on health reform

The insurance industry expresses what they want to get out of health care reform as efforts progress and attacks against them increase.

6 Aug 2009

Scientists create stem cells from developing sperm

The promise of stem cell therapy may lie in uncovering how adult cells revert back into a primordial, stem cell state, whose fate is yet to be determined. Now, cell scientists at the Johns Hopkins University School of Medicine have identified key molecular players responsible for this reversion in fruit fly sperm cells.

6 Aug 2009

Discovery of 'tell-tale' viral signature in blood that identifies underlying viral infection

Scientists have identified a genomic "signature" in circulating blood that reveals exposure to common upper respiratory viruses, like the cold or flu, even before symptoms appear.

6 Aug 2009

Hillary Clinton to meet with Somali President

As part of her seven country, 11-day trip to Africa, Secretary of State Hillary Rodham Clinton on Thursday in Nairobi will meet with Somali President Sheik Sharif Sheik Ahmed at the new U.S. embassy in Kenya, according to Associated Press (Lee, 8/6).

6 Aug 2009

Pattern of gene expression in blood provides clues to etiology of respiratory infections

Scientists have shown that they can identify and characterize an individual's response to a respiratory viral infection by examining the pattern of gene expression in their blood.

6 Aug 2009

Checking in with health insurers' chief lobbyist Karen Ignagni

This has become an especially rough-and-tumble time for Karen Ignagni, the health industry’s chief lobbyist. House Speaker Nancy Pelosi, D-Calif., has denounced insurers as “villains,” and President Obama has criticized the industry for its “windfall profits.” Earlier this year, Ignagni pledged to work with Obama and Congress to pass major health care legislation this year, but relations have cooled as the White House and congressional Democrats have begun citing the industry’s practices as a top reason to pass an overhaul of the nation’s health care system.

6 Aug 2009

Celera and Aurora to collaborate on cardiovascular genetics

Aurora Health Care, Wisconsin's largest health care provider, and Celera Corporation announced today that they have entered into an agreement to collaborate on the integration of genetic testing aimed at optimizing heart care for Aurora patients

6 Aug 2009

Bill Clinton, Pfizer, and Mylan announce new agreements to lower prices of antiretrovirals for HIV/AIDS in the developing world

President Bill Clinton announced two important and complementary agreements today to enable better, more affordable treatments for patients on second-line antiretroviral (ARV) therapy for HIV/AIDS in the developing world.

6 Aug 2009

Jealousy in relationships fuelled by Facebook!

The more time college students spend on Facebook, the more likely they are to feel jealous toward their romantic partners, leading to more time on Facebook searching for additional information that will further fuel their jealousy, in an escalating cycle that may become addictive, according to a study reported in CyberPsychology & Behavior, a peer-reviewed journal published by Mary Ann Liebert, Inc. (www.liebertpub.com). The article is available free online at www.liebertpub.com/cpb

6 Aug 2009

Big business group urges cost cutting to pay for health overhaul

John Castellani, the president of the Business Roundtable, told reporters today that health reform legislation should include mechanisms to finance coverage expansions largely through cost savings inside the health care system and should preserve ERISA, the 1974 federal law that regulates most private employee health plans.

6 Aug 2009

Automated network could predict disease outbreaks that originate in animals

The AP/San Francisco Chronicle examines Los Alamos National Laboratory researchers' efforts to create an automated network to monitor animals in an effort to predict disease outbreaks because two out of every three human diseases "originated in animals."

6 Aug 2009

Huge cost of scaling up entire health system in Sub-Saharan Africa

Hiring the nearly 800,000 workers needed to eliminate the staggering shortage of health care professionals in sub-Saharan Africa by 2015 will cost $2.6 billion a year, or 2.5 times the annual funds currently allocated for health worker wages in the region, according to a new study by researchers at the University of California, Berkeley, and collaborators from the World Health Organization (WHO) and The World Bank.

6 Aug 2009

Baucus/Grassley relationship challenged, other Senators weigh in on Rreform

The old reliable relationship between Sens. Max Baucus (D-Mont.) and Chuck Grassley (R-Iowa) continues to "bedevil" their Senate colleagues as the Finance Committee nears a deal on health care reform, Roll Call reports.

6 Aug 2009

Fast-tracked H1N1 vaccines will not compromise safety, WHO says

Efforts to fast-track the approval of H1N1 (swine) flu vaccines will not compromise the safety or quality controls of vaccine production, the WHO said in a written statement Thursday, the Mail & Guardian reports.

6 Aug 2009

Bloomberg examines China plague cases, potential for disease spread

"Plague-spreading fleas are expanding their territory, putting more people at risk of catching the lethal illness, a WHO official said," Bloomberg reports, in an article that examines the recent deaths of three people in China from the pneumonic plague.

6 Aug 2009

House left unfinished business when it left for August break

House members left Washington last week with some unfinished business: 55 to 60 pending amendments in the Energy and Commerce Committee, which became the last of three House panels to report its version of the health care overhaul late Friday night, Congress Daily reports.

6 Aug 2009

Beetroot juice boosts stamina, may help endurance athletes

Drinking beetroot juice boosts your stamina and could help you exercise for up to 16% longer. A University of Exeter led-study, published today (Thursday 6 August 2009), shows for the first time how the nitrate contained in beetroot juice leads to a reduction in oxygen uptake, making exercise less tiring.

6 Aug 2009