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Scientists develop new micropump for hand-held medical devices

In an advance toward analyzing blood and urine instantly at a patient's bedside instead of waiting for results from a central laboratory, scientists are reporting development of a new micropump capable of producing pressures almost 500 times higher than the pressure in a car tire. Described in ACS' journal Analytical Chemistry, the pumps are for futuristic "labs-on-a-chip," which reduce entire laboratories to the size of a postage stamp.

1 Nov 2012

Encouraging results from Gilead’s TAF Phase 2 trial on HIV-1 infection

Gilead Sciences, Inc. today announced that a Phase 2 clinical trial evaluating tenofovir alafenamide fumarate, an investigational novel prodrug of tenofovir for the treatment of HIV-1 infection, met its primary objective.

1 Nov 2012

Exosomes alone could protect infants' lungs from dangerous inflammation

Researchers at Boston Children's Hospital have found that microscopic particles containing proteins and nucleic acids called exosomes could potentially protect the fragile lungs of premature babies from serious lung diseases and chronic lung injury caused by inflammation.

1 Nov 2012

Controlling depression can improve health status and social functioning in patients with heart failure

Controlling depression in patients with heart failure can improve health status, social functioning and quality of life, according to a new study by psychiatrists and cardiologists at the UC Davis and Duke University schools of medicine.

1 Nov 2012

Scientists discover first selective inhibitors of DAGL enzymes

Scientists at The Scripps Research Institute (TSRI) have discovered the first selective inhibitors of an important set of enzymes. The new inhibitors, and chemical probes based on them, now can be used to study the functions of enzymes known as diacylglycerol lipases (DAGL), their products, and the pathways they regulate.

1 Nov 2012

Ceramide might play a leading role in muscle deterioration in older adults

As men and women age, increasing quantities of fat tissue inevitably take up residence in skeletal muscle. A small study of older and younger men conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University suggests that a build-up of a fat molecule known as ceramide might play a leading role in muscle deterioration in older adults.

1 Nov 2012

BWH researchers propose new model that shifts how we think about mindfulness

Achieving mindfulness through meditation has helped people maintain a healthy mind by quelling negative emotions and thoughts, such as desire, anger and anxiety, and encouraging more positive dispositions such as compassion, empathy and forgiveness. Those who have reaped the benefits of mindfulness know that it works. But how exactly does it work?

31 Oct 2012

Thermo Fisher launches Sorvall LYNX superspeed centrifuge series

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the new Thermo Scientific Sorvall LYNX superspeed centrifuge series, delivering productivity, safety and reliability to maximize everyday centrifuge use in shared laboratory settings.

From Thermo Fisher Scientific Inc. 31 Oct 2012

Intravenous catheter replacement: an interview with Claire Rickard

Peripheral intravenous catheters (“IV drips”) are small plastic tubes inserted into veins, most frequently in the hand or arm.

30 Oct 2012

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

30 Oct 2012

Scientists discover β2-syntrophin protein as new prognosis marker for prostate cancer

Scientists have discovered a molecular 'tell' in laboratory experiments that could help doctors determine the severity of a patient's prostate cancer.

30 Oct 2012

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key "software" instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL's "software" is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets.

29 Oct 2012

Botanical treatment holds hope for triple-negative breast cancer

A unique formula made from medicinal mushrooms, traditional Chinese herbs and other natural ingredients inhibits aggressive, human triple-negative breast cancer and breast-to-lung metastasis in mice. This is the third peer-reviewed study to demonstrate the botanical formula's anticancer effects.

29 Oct 2012

The App That's Transforming Blood Banking

An interview with Celia Tombalankian, discussing the benefits of automation in blood banking and the development of a new blood banking app.

From Ortho-Clinical Diagnostics, Inc. 29 Oct 2012

Light-sensitive protein to study Parkinson's disease

Introducing a light-sensitive protein in transgenic nerve cells... transplanting nerve cells into the brains of laboratory animals... inserting an optic fibre in the brain and using it to light up the nerve cells and stimulate them into releasing more dopamine to combat Parkinson's disease...

29 Oct 2012

Research team receives grant to study impact of urban air pollution on TB immunity

An international team of researchers, led by Stephan Schwander, MD, PhD, director of the Center for Global Public Health at the University of Medicine and Dentistry of New Jersey-School of Public Health, has received a $2.96 million grant to conduct a "real-world" study on the impact of urban air pollution on the human immune system's ability to resist Mycobacterium tuberculosis, the bacterium that causes tuberculosis.

29 Oct 2012

Researchers use baker's yeast to identify new therapies for Lou Gehrig's disease

Amyotrophic lateral sclerosis, also called Lou Gehrig's disease, is a devastatingly cruel neurodegenerative disorder that robs sufferers of the ability to move, speak and, finally, breathe.

29 Oct 2012

New HIV test for babies differs from conventional test, delivers diagnosis in less than an hour

Today, mothers in Africa sometimes walk more than 10 miles to a clinic only to learn that conventional HIV test results for their babies are not available yet.

29 Oct 2012

Scientists hope to unravel mystery of how Borrelia burgdorferi causes Lyme disease

Investigators at The University of Texas Health Science Center at Houston (UTHealth) have accelerated the search for the bacterial genes that make the Lyme disease bacterium so invasive and persistent. The discovery could advance the diagnosis and treatment of this disease, which affects an estimated 30,000 Americans each year.

29 Oct 2012

Researchers investigate unique features of arcuate neurons in the hypothalamus

Maintaining a healthy body weight may be difficult for many people, but it's reassuring to know that our brains and bodies are wired to work together to do just that-in essence, to achieve a phenomenon known as energy balance, a tight matching between the number of calories consumed versus those expended. This careful balance results from a complex interchange of neurobiological crosstalk within regions of the brain's hypothalamus, and when this "conversation" goes awry, obesity or anorexia can result.

29 Oct 2012

Laboratory News and Research

Scientists develop new micropump for hand-held medical devices

Encouraging results from Gilead’s TAF Phase 2 trial on HIV-1 infection

Exosomes alone could protect infants' lungs from dangerous inflammation

Controlling depression can improve health status and social functioning in patients with heart failure

Scientists discover first selective inhibitors of DAGL enzymes

Ceramide might play a leading role in muscle deterioration in older adults

BWH researchers propose new model that shifts how we think about mindfulness

Thermo Fisher launches Sorvall LYNX superspeed centrifuge series

Intravenous catheter replacement: an interview with Claire Rickard

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

Scientists discover β2-syntrophin protein as new prognosis marker for prostate cancer

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

Botanical treatment holds hope for triple-negative breast cancer

The App That's Transforming Blood Banking

Light-sensitive protein to study Parkinson's disease

Research team receives grant to study impact of urban air pollution on TB immunity

Researchers use baker's yeast to identify new therapies for Lou Gehrig's disease

New HIV test for babies differs from conventional test, delivers diagnosis in less than an hour

Scientists hope to unravel mystery of how Borrelia burgdorferi causes Lyme disease

Researchers investigate unique features of arcuate neurons in the hypothalamus

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