Chronic Pain News and Research

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Mutations in ion channels cause rare inherited pain disorder: Research

A mutation that enhances the function of a specific ion channel has been identified as the cause of a rare inherited pain disorder. The research, published by Cell Press in the June 10 issue of the journal Neuron, proposes a potential treatment for the disorder and may lead to a better understanding of chronic pain in humans.

10 Jun 2010

NIH awards Aestus $2M SBIR grant for clinical trials of treatment for chronic neuropathic pain

Aestus Therapeutics, Inc. announced that it has been awarded a $2 million Small Business Innovative Research (SBIR) grant from the National Institutes of Health (NIH). The grant, from the NIH's National Institute of Neurological Disorders and Stroke (NINDS), will fund clinical trials of Aestus's novel, first-in-class treatment for chronic neuropathic pain.

9 Jun 2010

Depressed mood makes pain more unpleasant

When it comes to pain, the two competing schools of thought are that it's either "all in your head" or "all in your body". A new study led by University of Oxford researchers indicates that, instead, pain is an amalgam of the two.

8 Jun 2010

Assured Pharmacy launches new website

Assured Pharmacy, a pharmacy service healthcare organization operating a chain of specialty pharmacies providing advanced prescription medication fulfillment solutions to sufferers of chronic pain, is pleased to announce the launch of its new website: www.assuredrxservices.com.

7 Jun 2010

Competitive Technologies to raise over $5M to accelerate sales of Calmare Pain Therapy Treatment

Competitive Technologies, Inc. today announced that it has signed an agreement to raise over $5 million by selling 2 million shares of equity to Crisnic Fund, S.A. based on a 15% discount from the volume weighted average price on the date the SEC declares the registration effective, as detailed in the 8-K being filed today.

2 Jun 2010

Meditation-based therapies benefit patients with chronic pain

People who meditate regularly find pain less unpleasant because their brains anticipate the pain less, a new study has found.

2 Jun 2010

UCI study provides blueprint for enhanced treatment of inflammatory diseases

By discovering how adult neural stem cells navigate to injury sites in the central nervous system, UC Irvine researchers have helped solve a puzzle in the creation of stem cell-based treatments: How do these cells know where to go? Tom Lane and Kevin Carbajal of the Sue and Bill Gross Stem Cell Research Center found the answer with the body's immune system.

2 Jun 2010

St. Jude Medical's Epiducer lead delivery system for neurostimulation therapy receives CE Mark approval

St. Jude Medical, Inc., a global medical device company, today announced European CE Mark approval of its new Epiducer™ lead delivery system for neurostimulation therapy. Unveiled at the Neurosurgery 2010 Congress in Lyon, France, the Epiducer lead delivery system is the first of its kind, allowing introduction of S-Series perc-paddle leads as well as multiple lead arrays through a single percutaneous entry point.

27 May 2010

Positive results reported from Phase IIa clinical trial of intranasal oxytocin for CDH

Trigemina, Inc., a Mountain View based privately-held biopharmaceutical company, reports positive results from a time-based interim analysis of its Phase IIa clinical trial in Chronic Daily Headache. The trial is a collaborative effort between Trigemina and Dr. Egilius Spierings of MedVadis Research Corporation located outside of Boston. The study compares intranasal oxytocin with placebo in patients suffering from CDH.

26 May 2010

Researchers develop new therapy for psychological treatment of patients suffering from fibromyalgia

Researchers of the Labpsictec at the Universitat Jaume I of Castellon and the LahHuman Group at the Universidad Politecnica of Valencia and the University of Valencia have developed a new therapy based on the use of mobile devices and virtual reality for the psychological treatment of patients suffering from fibromyalgia.

24 May 2010

CTT's Calmare Pain Therapy Treatment decreases pain associated with CIPN

Competitive Technologies, Inc. today announced the issuance of an abstract from a study which has shown the successful treatment of patients suffering from pain associated with chemotherapy-induced peripheral neuropathy using CTT's Calmare Pain Therapy Treatment.

21 May 2010

Psychological factors are major predictors of chronic pain in trauma patients, say researchers

Can long-term pain and disability be predicted in individuals recovering from non-life-threatening orthopedic injuries? A team of Australian researchers writing in The Journal of Pain, the peer review journal of the American Pain Society, www.ampainsoc.org, says yes and believes psychological factors, such as pessimism about recovery and depression, are major predictors of chronic pain in trauma patients.

20 May 2010

Studies suggest potent therapeutic effects of rufinamide in bipolar disorder, depressive and anxiety disorders

This study formulates the hypothesis that rufinamide, a drug so far used against epilepsy, may also be effective in bipolar disorder, depressive and anxiety disorders, panic disorder and obsessive-compulsive disorder, eating disorders, and substance use disorders. It is just an hypothesis based on two cases that needs to be confirmed by specific studies.

19 May 2010

TriReme Medical receives FDA expanded clearance for GliderXtreme PTA balloon catheter

TriReme Medical, Inc. (TMI) announced today that it has received FDA clearance for an expanded matrix of sizes for its GliderXtreme™ PTA balloon catheter. GliderXtreme™ is now approved for the percutaneous transluminal treatment of lesions in the peripheral vasculature in balloon diameters from 2.0 – 5.0mm and in balloon lengths up to 200mm.

17 May 2010

BUSM researchers identify clinical characteristics associated with PDUD in primary care patients

Researchers at Boston University School of Medicine have identified clinical characteristics associated with prescription drug use disorder in primary care patients with chronic pain. The study found that by identifying characteristics of prescription drug abuse, primary care clinicians can identify those at risk and provide appropriate treatment.

15 May 2010

Pain rehabilitation programs can help patients break the cycle of worsening pain: Mayo Clinic Health Letter

Chronic pain -- whether from headaches, back pain or conditions such as fibromyalgia -- can interfere with work, day-to-day activities and relationships. All too often, pain relief treatments are ineffective and can lead to a downward spiral of frustration, decreased functioning, stress, isolation -- and worsening pain.

13 May 2010

NIH awards PLx Pharma multiple grants for development of GI safer NSAIDs

PLx Pharma, a pharmaceutical company developing safer formulations of proven non-steroidal anti-inflammatory drugs (NSAIDs), today announced that it has been awarded multiple grants from the National Institutes of Health (NIH) totaling approximately $2,000,000. This funding has been awarded to support further advancement of a range of products currently under development by PLx.

12 May 2010

Progenics Pharmaceuticals reports net loss of $18.6M in first-quarter 2010

Progenics Pharmaceuticals, Inc. today announced its results of operations for the quarter ended March 31, 2010.

11 May 2010

QRxPharma reports successful outcome of Phase 1 trial for MoxDuo CR for chronic pain

QRxPharma announced today the successful outcome of a Phase 1 trial for MoxDuo CR, a controlled-release (CR) Dual-Opioid(TM) designed to provide 12 hours of pain relief in patients suffering from moderate to severe chronic pain (including cancer, lower back, osteoarthritis and neuropathic). The purpose of the trial was to determine which of the various experimental formulations provided the optimum duration of drug levels in the blood.

10 May 2010

Mice express pain through facial expressions, says study

A new study by researchers from McGill University and the University of British Columbia shows that mice, like humans, express pain through facial expressions.

10 May 2010

Chronic Pain News and Research

Mutations in ion channels cause rare inherited pain disorder: Research

NIH awards Aestus $2M SBIR grant for clinical trials of treatment for chronic neuropathic pain

Depressed mood makes pain more unpleasant

Assured Pharmacy launches new website

Competitive Technologies to raise over $5M to accelerate sales of Calmare Pain Therapy Treatment

Meditation-based therapies benefit patients with chronic pain

UCI study provides blueprint for enhanced treatment of inflammatory diseases

St. Jude Medical's Epiducer lead delivery system for neurostimulation therapy receives CE Mark approval

Positive results reported from Phase IIa clinical trial of intranasal oxytocin for CDH

Researchers develop new therapy for psychological treatment of patients suffering from fibromyalgia

CTT's Calmare Pain Therapy Treatment decreases pain associated with CIPN

Psychological factors are major predictors of chronic pain in trauma patients, say researchers

Studies suggest potent therapeutic effects of rufinamide in bipolar disorder, depressive and anxiety disorders

TriReme Medical receives FDA expanded clearance for GliderXtreme PTA balloon catheter

BUSM researchers identify clinical characteristics associated with PDUD in primary care patients

Pain rehabilitation programs can help patients break the cycle of worsening pain: Mayo Clinic Health Letter

NIH awards PLx Pharma multiple grants for development of GI safer NSAIDs

Progenics Pharmaceuticals reports net loss of $18.6M in first-quarter 2010

QRxPharma reports successful outcome of Phase 1 trial for MoxDuo CR for chronic pain

Mice express pain through facial expressions, says study

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