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Even moderate exercise helps keep the brain healthy

Scientists at the University of Queensland (UQ) say they have found that exercise helps keep the brain healthy and even moderate exercise directly increases the number of stem cells in the ageing brain.

28 Jun 2009

Heart attacks kill 10,000 Australians each year and many could be avoided

A new report by Access Economics has revealed that this year 80,000 Australians can expect to be treated in hospital for heart attacks or chest pain - at a cost to the economy of $18 billion and 10,000 people will die from a heart attack.

28 Jun 2009

Discovery of novel mechanism that could be targeted to prevent cancer spread

Researchers have discovered a key to the function of a specific protein that helps control the levels of other critical proteins within cells, including a protein that suppresses the spread of cancer. The new information about the mechanism of action of the protein, called gp78, may enable researchers to explore new types of therapies to prevent the spread of cancer. The study, by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, was published in the June 26, 2009, issue of Molecular Cell.

28 Jun 2009

Multiparameter computational modeling of tumor invasion

Tumors are complex collections of cells whose behavior has proven difficult to understand, let alone predict. As a result, oncologists are often surprised by how a particular patient responds to a given course of therapy.

28 Jun 2009

Nanofountain-probe-based high-resolution patterning and single-cell injection of functionalized nanodiamonds

A research team at Northwestern University has developed a tool that can precisely deliver tiny doses of drug-carrying nanomaterials to individual cells.

28 Jun 2009

Carbon nanotubes continue to show promise in battle against cancer

Carbon nanotubes, one of the original engineered nanomaterials, also may prove to be among the most versatile, as numerous teams of investigators continue to develop novel nanotube-based therapeutic and diagnostic tools. Over the past month, three new research papers have highlighted the potential of nanotubes as weapons against cancer.

28 Jun 2009

Nanofluidic biopsy detects subtle changes in cancer cells

By taking two standard laboratory techniques - capillary electrophoresis and antibody-based protein detection - and shrinking them to the nanoscale, researchers at the Stanford University School of Medicine have created a new method for detecting miniscule changes in the levels of proteins associated with cancer.

28 Jun 2009

Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy

An interdisciplinary team of researchers at Brigham and Women's Hospital and the Harvard-Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors.

28 Jun 2009

Computer-guided nanoparticle therapy destroys tumors

Gold nanoshells are among the most promising new nanoscale therapeutics being developed to kill tumors, acting as antennas that turn light energy into heat that cooks cancer to death. Now, a multi-institutional research team has shown that polymer-coated gold nanorods one-up their spherical counterparts, with a single dose completely destroying all tumors in a nonhuman animal model of human cancer.

28 Jun 2009

Enzyme fights mutated protein in inherited Parkinson's disease

An enzyme that naturally occurs in the brain helps destroy the mutated protein that is the most common cause of inherited Parkinson's disease, researchers at UT Southwestern Medical Center have found.

28 Jun 2009

Possible link between insulin glargine and cancer prompts urgent call for more research

The European Association for the Study of Diabetes (EASD) has made an urgent call for more research into a possible link between use of insulin glargine (an insulin analogue) and increased risk of cancer, following evidence from studies in Germany, Sweden and Scotland. However, until this further research becomes available, these experts are stressing that patients with diabetes taking Lantus should continue to do so, although some might wish to consider alternative types of insulin. The studies are reported in Diabetologia (the journal of EASD), edited by Professor Edwin Gale of the University of Bristol.

28 Jun 2009

New protein stabilisation technique could revolutionise therapeutic drug discovery

A revolutionary new protein stabilisation technique has been developed by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) which could lead to 30 per cent more proteins being available as potential targets for drug development - opening up exciting possibilities in drug discovery.

25 Jun 2009

Healthcare outcome boost needs better studies

Evidence suggests that outcomes in many clinical settings leave a lot to be desired, which means that research into quality improvement (QI) in clinical care has the potential to greatly improve the lot of patients. Now a study in the journal Medical Care Research and Review published by SAGE suggests that both theoretical and practical improvements in QI effectiveness studies could make these into much more powerful tools for positive change.

25 Jun 2009

Blood pressure cuff could help improve the success of kidney transplants

The first clinical trial funded by the new Efficacy and Mechanism Evaluation (EME) programme will investigate whether a simple procedure to activate one of the body's natural defence mechanisms improves the function of kidneys after transplantation. This research is funded by the Medical Research Council and managed by the National Institute for Health Research.

25 Jun 2009

HPV testing for cervical screening investigated

New research, published in The Lancet Oncology, has found that combining human papillomavirus (HPV) testing with routine liquid-based cytology (LBC) screening does not increase the detection of cervical cancer compared with LBC screening alone. The trial funded by the National Institute for Health Research Health Technology Assessment (NIHR HTA) programme aimed to determine whether testing for HPV in the cervix might increase the effectiveness of the cervical screening programme.

25 Jun 2009

Requirements for using e-health begin to emerge; public input needed, experts say

The American Recovery and Reinvestment Act (a.k.a. The Stimulus) set aside billions of dollars for hospitals to acquire electronic medical record systems, but one requirement for hospitals hoping to receive the money will be to share patient records with other facilities, the Dallas Morning News reports.

25 Jun 2009

Sources: Hospitals may strike deal to save $200 billion

Hospitals could sign on to an agreement with Senate health reform leader Max Baucus, D-Mont., and the White House to help save up to $200 billion as part of the overhaul plan, lobbyist and health industry sources tell Roll Call.

25 Jun 2009

Poll: Most want health reform but fear its side effects

"A majority of Americans see government action as critical to controlling runaway health-care costs, but there is broad public anxiety about the potential impact of reform legislation and conflicting views about the types of fixes being proposed on Capitol Hill, according to a new Washington Post-ABC News poll," The Washington Post reports.

25 Jun 2009