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UAH forms new Learning and Technology Resource Center to train student nurses

The University of Alabama in Huntsville College of Nursing has formed a new Learning and Technology Resource Center (LTRC) to consolidate its use of technology and lifelike patient simulators to train students and to further research in healthcare simulation education.

18 Dec 2014

Trophoblasts respond to inflammatory danger signals, find NTNU researchers

Trophoblasts, cells that form an outer layer around a fertilized egg and develop into the major part of the placenta, have now been shown to respond to inflammatory danger signals, researchers from Norwegian University of Science and Technology found in a recent study published in Journal of Reproductive Immunology December 2014.

18 Dec 2014

Researchers reveal common features responsible for antibiotic resistance

Treating bacterial infections with antibiotics is becoming increasingly difficult as bacteria develop resistance not only to the antibiotics being used against them, but also to ones they have never encountered before. By analyzing genetic and phenotypic changes in antibiotic-resistant strains of E. coli, researchers at the RIKEN Quantitative Biology Center in Japan have revealed a common set of features that appear to be responsible for the development of resistance to several types of antibiotics.

18 Dec 2014

Two orphan receptor proteins exert fatal double whammy effect against glioblastoma cells

Two related proteins exert a lethal double whammy effect against glioblastoma cells when activated with a small molecule, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

18 Dec 2014

High-dose flu vaccine better than regular flu shot for frail, older adults of long-term care facilities

The high-dose flu vaccine is significantly better than the regular flu shot at boosting the immune response to the flu virus in frail, older residents of long-term care facilities, according to the results of a University of Pittsburgh School of Medicine study.

18 Dec 2014

Eight researchers to receive 2015 Leibniz Prize

The new recipients of Germany's most prestigious research funding prize have been announced. In Bonn today, the Joint Committee of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) decided to award the 2015 Leibniz Prize to eight researchers.

18 Dec 2014

Study offers insights into mechanisms of bacterial resistance to antimicrobial peptides

Antimicrobial peptides are a distinctive class of potent, broad-spectrum antibiotics produced by the body's innate immune system--the first line of defense against disease-causing microbes.

18 Dec 2014

TSRI scientists discover new method for joining complex organic molecules

Chemists at The Scripps Research Institute have invented a powerful method for joining complex organic molecules that is extraordinarily robust and can be used to make pharmaceuticals, fabrics, dyes, plastics and other materials previously inaccessible to chemists.

18 Dec 2014

Researchers identify a single protein as root cause of multiple allergic reactions

Johns Hopkins and University of Alberta researchers have identified a single protein as the root of painful and dangerous allergic reactions to a range of medications and other substances. If a new drug can be found that targets the problematic protein, they say, it could help smooth treatment for patients with conditions ranging from prostate cancer to diabetes to HIV

17 Dec 2014

UCLA researchers develop lens-free microscope that can detect cancer, other cell-level abnormalities

UCLA researchers have developed a lens-free microscope that can be used to detect the presence of cancer or other cell-level abnormalities with the same accuracy as larger and more expensive optical microscopes.

17 Dec 2014

Universal Biosensors announces release of Siemens Xprecia Stride Coagulation Analyzer

Universal Biosensors, Inc. is pleased to announce that Siemens Healthcare Diagnostics Inc. has initiated the European limited release of the Xprecia Stride Coagulation Analyzer, its first point-of-care coagulation testing product.

17 Dec 2014

Investigational drug increases PFS in patients with advanced breast cancer

In a groundbreaking study that offers new hope for women with advanced breast cancer, researchers from UCLA's Jonsson Comprehensive Cancer Center have published final clinical trial results that showed the amount of time patients were on treatment without their cancer worsening (called progression-free survival) was effectively doubled in women with advanced breast cancer who took the experimental drug palbociclib.

17 Dec 2014

Mitochondrial DNA may predict overall risk of frailty, death

New research from The Johns Hopkins University suggests that the amount of mitochondrial DNA (mtDNA) found in peoples’ blood directly relates to how frail they are medically. This DNA may prove to be a useful predictor of overall risk of frailty and death from any cause 10 to 15 years before symptoms appear.

17 Dec 2014

UTSA receives NIH grant to develop bioinformatics tools to find cause of breast cancer

According to the American Cancer Society, breast cancer is the most common cancer among American women, except for skin cancers, and about one in eight women in the United States will develop invasive breast cancer during their lifetime. The National Institutes of Health recently awarded a $1.08 million grant to The University of Texas at San Antonio to combine computational modeling with biological information to advance our understanding of what may cause breast cells to become cancerous.

16 Dec 2014

CMC Biologics, OncoSynergy partner to develop novel potential treatment for Ebola

CMC Biologics and OncoSynergy have entered into an agreement for process development and GMP manufacture of OS2966 – a novel potential treatment for Ebola. The investigational drug candidate, designed to inhibit a major cellular adhesion receptor (CD29) that is fundamental for progression of aggressive and resistant cancer tumors, was granted orphan drug designation by the U.S. FDA earlier this year in the treatment of glioblastoma.

16 Dec 2014

Curie-Cancer, GamaMabs Pharma extend partnership to develop 3C23K drug for gynecological cancers

Curie-Cancer, the body responsible for developing Institut Curie’s industry partnership activities, and GamaMabs Pharma, a company specialized in the development of monoclonal antibodies for cancer, today announce the extension of their partnership to develop the 3C23K antibody for the treatment of gynecological cancers.

16 Dec 2014

PNNL to share variety of research at 2014 American Geophysical Union Fall Meeting

Scientists from the Department of Energy's Pacific Northwest National Laboratory will present a variety of research at the 2014 American Geophysical Union Fall Meeting, which runs Monday, Dec. 15 through Friday, Dec. 19 at the Moscone Convention Center in San Francisco.

16 Dec 2014

Penn study has implications for developing new cell-based treatments for skin disease

As the main component of connective tissue in the body, fibroblasts are the most common type of cell. Taking advantage of that ready availability, scientists from the Perelman School of Medicine at the University of Pennsylvania, the Wistar Institute, Boston University School of Medicine, and New Jersey Institute of Technology have discovered a way to repurpose fibroblasts into functional melanocytes, the body's pigment-producing cells.

16 Dec 2014

Sensitive toxicity test aims to detect dangerous side effects in pharmaceutical development

Because of undetected toxicity problems, about a third of prescription drugs approved in the U.S. are withdrawn from the market or require added warning labels limiting their use. An exceptionally sensitive toxicity test invented at the University of Utah could make it possible to uncover more of these dangerous side effects early in pharmaceutical development so that fewer patients are given unsafe drugs.

16 Dec 2014

Simple assessments can help prevent risk of passing Ebola virus disease from organ donor

While serious infections can be transmitted from donated organs, the risk of passing Ebola virus disease from an organ donor to a recipient is extremely small. In a new editorial published in the American Journal of Transplantation, experts explain how simple assessments of donors can help ensure that the organ supply is safe, while having little impact on the donor pool.

16 Dec 2014

Laboratory News and Research

UAH forms new Learning and Technology Resource Center to train student nurses

Trophoblasts respond to inflammatory danger signals, find NTNU researchers

Researchers reveal common features responsible for antibiotic resistance

Two orphan receptor proteins exert fatal double whammy effect against glioblastoma cells

High-dose flu vaccine better than regular flu shot for frail, older adults of long-term care facilities

Eight researchers to receive 2015 Leibniz Prize

Study offers insights into mechanisms of bacterial resistance to antimicrobial peptides

TSRI scientists discover new method for joining complex organic molecules

Researchers identify a single protein as root cause of multiple allergic reactions

UCLA researchers develop lens-free microscope that can detect cancer, other cell-level abnormalities

Universal Biosensors announces release of Siemens Xprecia Stride Coagulation Analyzer

Investigational drug increases PFS in patients with advanced breast cancer

Mitochondrial DNA may predict overall risk of frailty, death

UTSA receives NIH grant to develop bioinformatics tools to find cause of breast cancer

CMC Biologics, OncoSynergy partner to develop novel potential treatment for Ebola

Curie-Cancer, GamaMabs Pharma extend partnership to develop 3C23K drug for gynecological cancers

PNNL to share variety of research at 2014 American Geophysical Union Fall Meeting

Penn study has implications for developing new cell-based treatments for skin disease

Sensitive toxicity test aims to detect dangerous side effects in pharmaceutical development

Simple assessments can help prevent risk of passing Ebola virus disease from organ donor

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