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$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017

Millennials regret opioid use, prefer lifestyle changes to manage pain

Often spending their days hunched over phones, tablets or computers and their free time at spin class or playing sports, millennials are the next generation poised to experience chronic pain. Even at their young age, millennials say acute and chronic pain are already interfering with their quality of life.

30 Aug 2017

People with cardiac arrest in black neighborhoods less likely to receive bystander CPR

Surviving cardiac arrest often seems like a matter of luck -- whether a passerby knows CPR, or a defibrillator is close at hand or the ambulance arrives quickly.

30 Aug 2017

Rugby players take part in major study to develop ground-breaking test for concussion diagnosis

Rugby players from Aviva Premiership Rugby and Greene King IPA Championship are to take part in a major study led by the University of Birmingham as part of its work to develop a ground-breaking pitch-side test to diagnose concussion and brain injury.

30 Aug 2017

Decreasing sedentary time 21 minutes per day can help maintain muscle mass, health

Finnish researchers conducted one of the largest and longest studies to find out if it is possible to reduce sedentary time and if the reduction will result in any health benefits during one year.

30 Aug 2017

Nurses' scrubs with antimicrobial properties ineffective at preventing bacterial contamination

Clothing worn by healthcare providers can become contaminated with bacteria, however having nurses wear scrubs with antimicrobial properties did not prevent this bacterial contamination from occurring, according to a study published online today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

30 Aug 2017

Tiny tears in membranes of bone cells may be key to strong bones

The force gravity and physical activity put on our bones causes tiny tears in the membranes of the tiny cells that enable us to make or break down bone, scientists say.

29 Aug 2017

Excluding children from school may lead to long- term psychiatric problems, study shows

Excluding children from school may lead to long- term psychiatric problems and psychological distress, a study of thousands of children has shown.

29 Aug 2017

Low-dose hormone therapy may be effective in easing sleep issues for recently menopausal women

For many women, the side effects of menopause don't call it a day when they do. Between 40 and 60 percent of women in perimenopause and early menopause face issues with sleep because of this physical change. The majority also report hot flashes and night sweats, which can be disruptive to falling and staying asleep.

29 Aug 2017

Study links psoriasis severity to increased risk of death

The more the surface area of the body is covered by psoriasis, the greater the risk of death for the patient suffering from the condition, according to a new analysis by researchers in the Perelman School of Medicine at the University of Pennsylvania.

29 Aug 2017

Placenta-on-a-chip device mimics microenvironment of malaria in the womb to develop treatments

Malaria, one of the most severe public health problems, affected 212 million people worldwide in 2015. This life-threatening disease is caused by parasites that are transmitted to humans through the bites of infected female Anopheles mosquitoes.

29 Aug 2017

Boosting blood levels of bone-derived hormone may reverse age-related memory loss

Age-related memory loss may be reversed by boosting blood levels of osteocalcin, a hormone produced by bone cells, according to mouse studies led by Columbia University Medical Center researchers.

29 Aug 2017

Study provides insights into prediction and prevention of Asian dust-related acute myocardial infarctions

When Asian dust clouds blow in to Japan's Kumamoto Prefecture, hospitals in the region handle a surge of acute myocardial infarctions (AMI) in the following 24 hours, and now a new prediction tool could help pinpoint which patients are at greatest risk.

29 Aug 2017

Vast majority of melanoma appears on the skin as new spots, say researchers

As the summer draws to a close, it's time to start putting away flip-flops, bathing suits and beach bags. But as the seasonal supplies disappear into the back of the closet, sunscreen should stay within arm's reach for year-round protection against the sun's ultraviolet rays.

29 Aug 2017

Undergraduates earn top prize for developing new tool to detect Alzheimer’s disease

A team of seven University of Maryland A. James Clark School of Engineering undergraduates earned the top prize in this year's National Institutes of Health Design by Biomedical Undergraduate Teams challenge for their efforts to develop low-cost tools to diagnose Alzheimer's disease before patients show symptoms.

29 Aug 2017

Exercise plus calorie reduction may help improve muscle function in older adults

Improved muscle performance starts with better mitochondrial function. Older adults who are overweight may improve their muscle function with a weight loss program that combines exercise and calorie reduction, according to researchers from Florida Hospital, in Orlando, Fla., who present their findings today at the American Physiological Society's Physiological Bioenergetics: Mitochondria from Bench to Bedside conference in San Diego.

29 Aug 2017

Study tests therapeutic effect of conventional and new cancer drug combinations

Cancer is one of the major causes of death worldwide affecting 8.2 million of people per year, and in the US, the number of new cases will achieve 1.6 million in 2017. The global impact of this disease costs a trillion of dollars, which makes critical the development of new drugs and treatment against it.

28 Aug 2017

Substitution of gasoline for ethanol in dual-fuel vehicles increases level of polluting nanoparticles

When ethanol prices at the pump rise for whatever reason, it becomes economically advantageous for drivers of dual-fuel vehicles to fill up with gasoline.

28 Aug 2017

Compounds found in cocoa could help combat diabetes, say BYU researchers

What if eating chocolate helped prevent and treat diabetes? It's crazy enough to laugh off. But here's the thing: BYU researchers have discovered certain compounds found in cocoa can actually help your body release more insulin and respond to increased blood glucose better. Insulin is the hormone that manages glucose, the blood sugar that reaches unhealthy levels in diabetes.

28 Aug 2017

Weight gain early in pregnancy has greatest impact on infants' size at birth, study suggests

Weight gain in early pregnancy has the greatest impact on infant size at birth, according to a new study published today in Obesity. The study is the largest ever analysis of the effect that weight gain in early pregnancy has on infant size.

28 Aug 2017

Education News and Research

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Millennials regret opioid use, prefer lifestyle changes to manage pain

People with cardiac arrest in black neighborhoods less likely to receive bystander CPR

Rugby players take part in major study to develop ground-breaking test for concussion diagnosis

Decreasing sedentary time 21 minutes per day can help maintain muscle mass, health

Nurses' scrubs with antimicrobial properties ineffective at preventing bacterial contamination

Tiny tears in membranes of bone cells may be key to strong bones

Excluding children from school may lead to long- term psychiatric problems, study shows

Low-dose hormone therapy may be effective in easing sleep issues for recently menopausal women

Study links psoriasis severity to increased risk of death

Placenta-on-a-chip device mimics microenvironment of malaria in the womb to develop treatments

Boosting blood levels of bone-derived hormone may reverse age-related memory loss

Study provides insights into prediction and prevention of Asian dust-related acute myocardial infarctions

Vast majority of melanoma appears on the skin as new spots, say researchers

Undergraduates earn top prize for developing new tool to detect Alzheimer’s disease

Exercise plus calorie reduction may help improve muscle function in older adults

Study tests therapeutic effect of conventional and new cancer drug combinations

Substitution of gasoline for ethanol in dual-fuel vehicles increases level of polluting nanoparticles

Compounds found in cocoa could help combat diabetes, say BYU researchers

Weight gain early in pregnancy has greatest impact on infants' size at birth, study suggests

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