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Studies examine how PML gene regulates the fatty acid oxidation pathway

Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, highlight both the challenges and opportunities of genetic approaches to cancer treatment.

31 Aug 2012

Quest Diagnostics announces availability of TERC test for cervical cancer

Quest Diagnostics, the world's leading provider of diagnostic testing, information and services, today announced the availability of a new laboratory test that identifies molecular changes to cervical cells that increase the likelihood a woman may develop cervical cancer.

From Quest Diagnostics 31 Aug 2012

PD0325901 drug may hold potential to prevent neurofibromatosis 1 in children

A drug originally developed to stop cancerous tumors may hold the potential to prevent abnormal brain cell growth and learning disabilities in some children, if they can be diagnosed early enough, a new animal study suggests.

31 Aug 2012

New antibacterial coating on surgical sutures effectively reduces infections

Responding to an urgent need for better antibacterial coatings on surgical sutures, scientists are reporting the discovery of a new coating that is almost 1,000 times more effective than the most widely used commercial coating.

31 Aug 2012

Drug-resistant tuberculosis levels described as alarming by international study

A large, international study published Online First in The Lancet reveals alarming levels of tuberculosis (TB) that are resistant to both first-line and second-line drugs. The findings show high prevalence of resistance to at least one second-line drug (43.7%) among multidrug-resistant (MDR) TB patients from eight countries in Africa, Asia, Europe, and Latin America. Worse still, the study found higher than expected overall levels of extensively drug-resistant (XDR) TB.

30 Aug 2012

UAB Center of Research Translation to improve health of patients with gout, hyperuricemia

The University of Alabama at Birmingham is establishing a Center of Research Translation to improve the health of an increasing number of patients with gout and hyperuricemia.

30 Aug 2012

SureGene selects PGXL as laboratory provider for STA2R genetic panel

SureGene has chosen PGXL as laboratory provider for its proprietary STA2R genetic panel, which promises to revolutionize the treatment of schizophrenia.

30 Aug 2012

PrecisionMed announces enrollment of first donor into Amyotrophic Lateral Sclerosis Registry

PrecisionMed Inc., the world's leading supplier of human cerebrospinal fluid (CSF), today announced enrollment of the first donor into the PrecisionMed Amyotrophic Lateral Sclerosis (ALS) Registry.

30 Aug 2012

Sleep disorder treatment: an interview with Dr Seth Lederman, President and CEO of Tonix Pharmaceuticals

Sleep disorders are a large area. We are focused on one particular type of sleep disturbance called “non-restorative” sleep. People with this problem do sleep, but they don’t wake up feeling refreshed or feeling that their sleep has had the restorative effects of healthy sleep.

29 Aug 2012

Study shows molecular mechanism behind type 3c pancreatic diabetes

Mice develop pancreatic diabetes (type 3c) when they lack certain genes in the E2F group, and to understand how this happens, Olatz Zenarruzabeitia has focussed on the molecular mechanism behind it.

29 Aug 2012

New method simplifies pharmaceutical production of proteins

Engineering researchers at the University of Arkansas have developed a method to simplify the pharmaceutical production of proteins used in drugs that treat a variety of diseases and health conditions, including diabetes, cancer, arthritis and macular degeneration.

29 Aug 2012

Anova Cancer Care to participate in CyberKnife research study

Anova Cancer Care has been chosen to participate in a landmark national prostate cancer study. The goal of the two-year study is to determine the best treatments for prostate cancer. The study will look specifically at prostate cancer radiosurgery.

29 Aug 2012

Trudeau Institute study holds promise for improved prevention and treatment of bacterial infections

New research from the laboratory of Dr. Andrea Cooper at the Trudeau Institute, just published in the European Journal of Immunology, holds promise for the improved prevention and treatment of bacterial infections and the life-threatening complications of chronic inflammation that can result from them.

29 Aug 2012

NYU-Poly creates ultra-sensitive biosensor to identify small single virus particles

Researchers at Polytechnic Institute of New York University (NYU-Poly) have created an ultra-sensitive biosensor capable of identifying the smallest single virus particles in solution, an advance that may revolutionize early disease detection in a point-of-care setting and shrink test result wait times from weeks to minutes.

29 Aug 2012

Ultra-fast 320-detector CT scanner can accurately diagnose arterial blockages

An ultra-fast, 320-detector computed tomography (CT) scanner can accurately sort out which people with chest pain need - or don't need - an invasive procedure such as cardiac angioplasty or bypass surgery to restore blood flow to the heart, according to an international study. Results of the study, which involved 381 patients at 16 hospitals in eight countries, are scheduled to be presented at the European Society of Cardiology Congress in Munich, Germany, on August 28.

29 Aug 2012

Scientists identify genes that underlie growth of primitive leukemia stem cells

University of Rochester Medical Center scientists believe they are the first to identify genes that underlie the growth of primitive leukemia stem cells, and then to use the new genetic signature to identify currently available drugs that selectively target the rogue cells.

29 Aug 2012

Abbott receives CE Marking for ARCHITECT testosterone assay

Abbott announced today CE Marking (Conformite Europeenne) for a testosterone assay with improved sensitivity and clinical utility.

28 Aug 2012

High doses of vitamin B3 stimulate CEBPE gene, enhance WBCs’ ability to combat staph infections

Cedars-Sinai researchers have found that a common vitamin may have the potential to provide a powerful weapon to fight certain "superbugs," antibiotic-resistant staph infections that health experts see as a threat to public health.

28 Aug 2012

Friedreich Ataxia Research Alliance, USF ARC to host ‘Understanding a Cure’ symposium

Scientists, clinicians and patients will gather at the University of South Florida's Center for Advanced Medical Learning and Simulation (CAMLS) in downtown Tampa Sept. 6 to share research insights and energize the search for a cure for Friedreich's ataxia and related disorders.

28 Aug 2012

Rural and urban areas equally likely to receive endovascular aneurysm repair care

A new study published in the September issue of Journal of Vascular Surgery reveals that rural and urban patients have equivalent access to endovascular aneurysm repair (EVAR) care from vascular surgeons, increased referral to high-volume hospitals and improved outcomes after repair.

28 Aug 2012

Laboratory News and Research

Studies examine how PML gene regulates the fatty acid oxidation pathway

Quest Diagnostics announces availability of TERC test for cervical cancer

PD0325901 drug may hold potential to prevent neurofibromatosis 1 in children

New antibacterial coating on surgical sutures effectively reduces infections

Drug-resistant tuberculosis levels described as alarming by international study

UAB Center of Research Translation to improve health of patients with gout, hyperuricemia

SureGene selects PGXL as laboratory provider for STA2R genetic panel

PrecisionMed announces enrollment of first donor into Amyotrophic Lateral Sclerosis Registry

Sleep disorder treatment: an interview with Dr Seth Lederman, President and CEO of Tonix Pharmaceuticals

Study shows molecular mechanism behind type 3c pancreatic diabetes

New method simplifies pharmaceutical production of proteins

Anova Cancer Care to participate in CyberKnife research study

Trudeau Institute study holds promise for improved prevention and treatment of bacterial infections

NYU-Poly creates ultra-sensitive biosensor to identify small single virus particles

Ultra-fast 320-detector CT scanner can accurately diagnose arterial blockages

Scientists identify genes that underlie growth of primitive leukemia stem cells

Abbott receives CE Marking for ARCHITECT testosterone assay

High doses of vitamin B3 stimulate CEBPE gene, enhance WBCs’ ability to combat staph infections

Friedreich Ataxia Research Alliance, USF ARC to host ‘Understanding a Cure’ symposium

Rural and urban areas equally likely to receive endovascular aneurysm repair care

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