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Stun guns can cause brain-specific complications such as seizures

Stun guns, in certain circumstances, may result in brain-specific complications such as seizures, according to a new case report published in CMAJ http://www.cmaj.ca/press/pg625.pdf.

16 Mar 2009

Shire withdraws European application for Daytrana (Methylphenidate Transdermal System)

Shire plc has announced that it has decided to withdraw the European Marketing Authorization Application (MAA) for Daytrana (methylphenidate transdermal system) for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).

16 Mar 2009

Search for blood pressure secrets reveals a surprising new syndrome

Yale researchers investigating the genetic causes of blood pressure variation have identified a previously undescribed syndrome associated with seizures, a lack of coordination, developmental delay and hearing loss.

16 Mar 2009

FTO obesity gene associated with susceptibility to polycystic ovary syndrome

Researchers have shown that a gene implicated in the development of obesity is also associated with susceptibility to polycystic ovary syndrome (PCOS).

16 Mar 2009

Metabolic syndrome can help identify diabetes risk in Aboriginal Canadians

Metabolic syndrome is the clustering of risk factors associated with diabetes and heart disease, such as obesity, high cholesterol, high glucose and hypertension.

16 Mar 2009

Does stress damage the brain?

In the March 1st issue of Biological Psychiatry, published by Elsevier, a paper by Tibor Hajszan and colleagues provides an important new chapter to this question.

16 Mar 2009

Potential pathway for drug intervention

A newly identified molecular pathway that directs stem cells to produce glial cells yields insights into the neurobiology of Down's syndrome and a number of central nervous system disorders characterized by too many glial cells, according to a recent study by researchers at the Salk Institute for Biological Studies.

15 Mar 2009

Schering-Plough's investigational oral thrombin receptor antagonist meets primary endpoint in a newly published study

Results of a Schering-Plough Corporation Phase II trial of SCH 530348, a novel oral thrombin receptor antagonist (TRA), were published today in The Lancet and demonstrated that the investigational antiplatelet compound met its primary endpoints of safety and tolerability.

12 Mar 2009

New project to develop blood tests for heart disease and stroke

The landmark Framingham Heart Study (FHS) is launching a major initiative to discover risk factors and markers that could lead to new blood tests to identify individuals at high risk of heart disease and stroke.

12 Mar 2009

Research shed new light on anergia

With the help of a non-invasive method of monitoring human activity, doctors and researchers at Columbia University Medical Center are shedding new light on a syndrome affecting nearly 40 percent of older adults with heart failure: anergia.

11 Mar 2009

Toxoplasmosis linked to schizophrenia, bipolar disorders

Scientists have discovered how the toxoplasmosis parasite may trigger the development of schizophrenia and other bipolar disorders.

11 Mar 2009

Study of Rituxan (rituximab) in lupus nephritis misses primary endpoint

Genentech, Inc. and Biogen Idec has announced that a Phase III study of Rituxan (rituximab) plus mycophenolate mofetil (MMF) and corticosteroids in patients with lupus nephritis did not meet its primary endpoint of significantly reducing disease activity at 52 weeks.

11 Mar 2009

Mandatory obstructive sleep apnea screenings could reduce risk of truck crashes

Truck crashes are a significant public health hazard causing thousands of deaths and injuries each year, with driver fatigue and sleepiness being major causes.

11 Mar 2009

Novel anti-inflammatory therapy protects lungs from runaway inflammation

A novel anti-inflammatory therapy designed by Vanderbilt University Medical Center investigators prevents acute lung injury in mice exposed to an inflammation-causing toxin, the researchers report in the journal Molecular Therapy.

11 Mar 2009

Low levels of vitamin D linked to several risk factors in teenagers

Low levels of vitamin D were associated with an increased risk of high blood pressure, high blood sugar and metabolic syndrome in teenagers, researchers reported at the American Heart Association's 49th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

11 Mar 2009

Iron may be a suitable approach for developing novel cancer treatments

Rapid growth of cancer cells and their frequent divisions have their price: Cancer cells need considerably more energy than healthy cells.

11 Mar 2009

Risk factors for flat head syndrome

A new study by physician researchers from Hasbro Children's Hospital and Children's Hospital Boston identifies risk factors for the severity of asymmetrical head shapes, known as deformational plagiocephaly (DP), or more commonly as flat head syndrome.

11 Mar 2009

Metabolic and neurological disorders may share common risk factors

Metabolic disorders such as obesity and diabetes appear to share risk factors with and may influence the development of Alzheimer's disease and other forms of dementia, according to several reports published in the March issue of Archives of Neurology.

10 Mar 2009

Insomnia often a persistent condition

About three-fourths of individuals with insomnia report experiencing the condition for at least one year and almost half experience it for three years, according to a report in the March 9 issue of Archives of Internal Medicine.

10 Mar 2009

Diabetes and elevated levels of cholesterol linked to faster cognitive decline in Alzheimer's patients

A history of diabetes and elevated levels of cholesterol, especially LDL cholesterol, are associated with faster cognitive decline in patients with Alzheimer's disease, according to a new study from Columbia University Medical Center researchers.

10 Mar 2009