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Scientists identify 'border patrol agents' in the gut

Researchers at UT Southwestern Medical Center have shown in mice how and under what circumstances the gut activates its defensive mechanisms to prevent illness.

8 Dec 2008

Promising trials of malaria vaccine in East Africa lead to calls for phase 3 development

Experts are recommending that a malaria vaccine progress to Phase 3 trials following the successful trial of the RTS, S/AS01E malaria vaccine among 5-17 month old children in Korogwe, Tanzania and coastal Kenya, which is reported in the New England Journal of Medicine (NEJM).

8 Dec 2008

Thiamine reverses early diabetic kidney disease

Researchers at the University of Warwick have discovered high doses of thiamine - vitamin B1 - can reverse the onset of early diabetic kidney disease.

8 Dec 2008

Osmium as a cancer treatment

A precious metal which has never before been used in a clinical setting is being developed as an anti-cancer agent by University of Warwick researchers.

8 Dec 2008

Glowing imaging compound allows detection of viable cancer cells in mice

Researchers have developed a new type of imaging compound that allows them to visualize viable breast cancer cells that have spread to the lungs in mice.

8 Dec 2008

Novel approach to disseminate trial results to study volunteers

While an estimated 2.3 million people in the U.S. take part in clinical trials every year, there currently exists no formal requirement to inform them of study results; an oversight that leaves participants confused, frustrated, and, in some cases, lacking information that may be important to their health.

8 Dec 2008

New chemotherapy pill shows promise for stubborn lymphomas

A new chemotherapy pill is showing early success in treating people with stubborn lymphomas, according to scientists at the University of Rochester Medical Center. Doctors reported that the drug is halting disease in nearly half of the patients with chronic lymphocytic leukemia, and in patients with more aggressive lymphoma as well.

8 Dec 2008

Gene therapy used to fight AIDS

The apparent success of a case in which German doctors cured a man of AIDS using a bone marrow transplant comes as no surprise to Gerhard Bauer, a UC Davis stem cell researcher.

8 Dec 2008

Discovery of six novel genetic variants associated with lipid levels

A new study presages a real aim of genetics: to look at whole populations to in order determine the significance of individual genetic variants for individual health.

8 Dec 2008

Discovery of 11 new gene sites that influence cholesterol or triglyceride levels

An international research team has identified 11 novel locations in the human genome where common variations appear to influence cholesterol or triglyceride levels, bringing the total number of lipid-associated genes to 30.

8 Dec 2008

Researchers identify key step in maturation pathway of telomerase

The Stowers Institute's Baumann Lab has discovered an important step in the maturation pathway of telomerase, the enzyme that replenishes the sequences that are lost at chromosome ends with every cell division.

8 Dec 2008

Breathtaking stats in second hand smoke exposure and women's fertility

If you need another reason to quit smoking, consider that it may diminish your chances of being a parent or grandparent.

8 Dec 2008

Rituxan in combination with chemo improves survival in chronic lymphocytic leukemia

Genentech, Inc. and Biogen Idec have announced that two global Phase III studies in chronic lymphocytic leukemia (CLL), CLL8 and REACH, showed Rituxan (rituximab) plus chemotherapy significantly increased the time patients lived without their disease advancing, as defined by the primary endpoint of progression-free survival (PFS), when compared to chemotherapy alone.

8 Dec 2008

Effects of stem cell source and patient age on stem cell transplantation outcomes

Two studies examining the effects of stem cell source and patient age on stem cell transplantation outcomes were explored at a press conference on Sunday, December 7 during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA.

8 Dec 2008

New approaches to prevent blood clots

The largest study ever to examine the preventive use of blood-thinning medication to help prevent deadly blood clots in patients with cancer undergoing chemotherapy presented December 7 during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA.

8 Dec 2008

Age has no impact on survival after bone marrow transplant

Age alone should not determine whether an older patient with acute myeloid leukemia or myelodysplastic syndrome receives a blood stem cell transplant from a matched donor, researchers of the Center for International Blood and Marrow Transplant Research reported today at the 50th annual meeting of the American Society of Hematology.

8 Dec 2008

Hemichannels - new target to treat epileptic seizures following brain trauma or stroke

New therapies for some forms of epilepsy may soon be possible, thanks to a discovery made by a team of University of British Columbia and Vancouver Coastal Health Research Institute neuroscience researchers.

8 Dec 2008

New research reports on interventions that may alter the course of epilepsy diagnosis and management

Early diagnosis and treatment that quickly achieves seizure freedom with nominal side effects is the key goal to epilepsy management.

8 Dec 2008

Scientists create infectious prion disease in mouse model

A worldwide group of scientists has created an infectious prion disease in a mouse model, in a step that may help unravel the mystery of this progressive disease that affects the nervous system in humans and animals.

8 Dec 2008

Brain's circuitry survives longer than previously thought in Alzheimer's

Researchers at the Babraham Institute near Cambridge, supported by the Alzheimer's Research Trust and the Biotechnology and Biological Sciences Research Council (BBSRC), have discovered that the brain's circuitry survives longer than previously thought in diseases of ageing such as Alzheimer's disease.

8 Dec 2008