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Analysis of tissue biomarkers expressed in ovarian cancer samples

Although ovarian cancer is not the most common gynecologic cancer in women, the disease contributes a substantial burden of mortality in part because symptoms are nonspecific and the disease presents late in its course.

1 Dec 2008

Six bad bugs increasingly escaping effects of antibiotics

Infectious disease experts warn that new drugs are urgently needed to treat six drug-resistant bacteria that cause most hospital infections and increasingly escape the effects of antibiotics.

1 Dec 2008

Babies exposed to tobacco in utero more irritable, difficult to soothe

Previous studies have shown that babies exposed to tobacco in utero are more likely to have a low birth weight and are at increased risk for sudden infant death syndrome.

1 Dec 2008

Scientists discover new properties of imidazolium salts

Scientists at Singapore's Institute of Bioengineering and Nanotechnology (IBN) have uncovered new properties of imidazolium salts (IMSs), which suggest that they could play a vital role in disease prevention and treatment.

1 Dec 2008

New imaging technique captures clinical stages of ocular inflammation

Researchers used a new imaging technique to take high quality color photographs of the clinical stages of ocular inflammation in mice, and the technology could help in the monitoring and treatment of diseases of the eye that may cause blindness.

1 Dec 2008

Breakthrough in strategy used to develop new pharmacological treatments for schizophrenia

In one of the first instances of targeted drug design in psychiatric treatment, University of Pittsburgh researchers have found an experimental agent that shows promise in addressing working memory impairments that occur in schizophrenia.

1 Dec 2008

The coming surgeon shortage

In less than two years, there may not be enough surgeons in U.S. hospitals to treat the critically injured or chronically ill.

1 Dec 2008

Magnetic imaging devices may damage cochlear implants

Patients with cochlear implants may want to steer clear of certain magnetic imaging devices, such as 3T MRI machines, because the machines can demagnetize the patient's implant, according to new research published in the December 2008 issue of Otolaryngology - Head and Neck Surgery.

1 Dec 2008

Etanercept found to be ineffective in treating alcoholic hepatitis

A new study from Mayo Clinic finds the use of the drug therapy etanercept ineffective in treating alcoholic hepatitis, an acute inflammation of the liver caused by excessive consumption of alcohol. The results of the study are published in the December issue of Gastroenterology.

1 Dec 2008

Exposure to folic acid antagonists during pregnancy has risks

Exposure to folic acid antagonists during pregnancy is associated with a higher risk of placenta-mediated adverse outcomes such as preeclampsia, placental abruption, fetal growth restriction or fetal death reports a retrospective cohort study published in CMAJ.

1 Dec 2008

Dramatic procedural results for pectus excavatum patients

Patients who have had the common chest wall deformity known as pectus excavatum corrected report improved body image and ability to exercise, according to a study published December in the journal Pediatrics.

1 Dec 2008

New insight into adhesion and migration of dendritic cells could lead to novel cancer treatments

Our immune system plays an essential role in protecting us from diseases, but how does it do this exactly?

1 Dec 2008

Protein indoleamine 2,3-dioxygenase points to new pancreatic cancer therapies

An enzyme that is overexpressed in pancreatic cancer cells may hold the key to successfully treating the disease with targeted immunotherapy, researchers from Thomas Jefferson University reported at the 2008 Annual Meeting of the Southern Surgical Association.

1 Dec 2008

GeoVax's HIV/AIDS human vaccine trials to begin in North and South America

GeoVax Labs, Inc. has announced that the launch of its Phase 2a Human Vaccine Trials will take place in twelve sites across North and South America.

1 Dec 2008

Fractional dose of scarce meningitis vaccine may be effective in outbreak control

A partial dose of a commonly used vaccine against meningitis may be as effective as a full dose, according to new research published December 2 in the open-access journal PLoS Neglected Tropical Diseases.

1 Dec 2008

Study looks at rare injuries in high school athletes

Rare injuries accounted for 3.5 percent of high school athletes' injuries 2005 through 2007, according to the first study to examine rare injuries and conditions of U.S. high school athletes.

1 Dec 2008

Alcohol-dependence study looks at impact of pharmacotherapy on quality-of-life

Most studies examining the impact of alcohol-dependence (AD) treatment on quality-of-life (QOL) have looked at psychosocial treatments.

1 Dec 2008

Latin women of European ancestry at greater risk for breast cancer

Latina women have a lower risk of breast cancer than European or African-American women generally, but those with higher European ancestry could be at increased risk, according to data published in the December 1 issue of Cancer Research , a journal of the American Association for Cancer Research.

1 Dec 2008

Researchers find that when cells shut down they also spew proteins into their surrounding environment

Cells shut down and stop dividing when their DNA is damaged, in a process known as cellular senescence, so as to prevent damaged DNA from leading to unregulated cell division and therefore cancer.

1 Dec 2008