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New vaccine principle delivers stronger and faster immune response

A new vaccine principle is being developed by scientists at the University of Copenhagen which - if it works to its full expected potential - could help to save millions of lives and revolutionise current vaccine technology.

24 Nov 2008

Obama's team presented with policy recommendations designed to combat obesity epidemic

President-elect Barack Obama's Health and Human Services Transition Team was presented with a series of nearly 50 legal and policy recommendations designed to combat the nation's obesity epidemic.

24 Nov 2008

HHS releases first-ever inventory of quality measures

The Department of Health and Human Services (HHS) has released the first-ever inventory of quality measures that are used for reporting, payment, or quality improvement by its agencies and operating divisions.

24 Nov 2008

Medarex starts phase 1b clinical trial with MDX-1106 for the treatment of cancer

Medarex, Inc. has announced it has initiated a Phase 1b clinical trial for MDX-1106 (ONO-4538: development code of Ono Pharmaceutical Co., Ltd.), a fully human anti-PD-1 antibody for the treatment of cancer.

24 Nov 2008

Mammograms may detect some cancers that would have otherwise regressed

Breast cancer rates increased significantly in four Norwegian counties after women there began undergoing mammography every two years, according to a report in the November 24 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

24 Nov 2008

Hospital admissions for lung cancer stable

Hospital admissions for lung cancer remained relatively stable - at roughly 150,000 a year between 1995 and 2006 - despite a steady decline in the number of Americans diagnosed with the disease, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

24 Nov 2008

New hope for lung disease pulmonary alveolar proteinosis

A tale of two sisters has helped researchers solve a medical mystery and discover a familial genetic mutation that causes an inherited form of the lung disease Pulmonary Alveolar Proteinosis (PAP).

24 Nov 2008

Health study in northern Uganda calls for improved services for internally displaced persons

There are over 1 million internally displaced persons (IDPs) in Uganda due to the 20-year conflict waged between a rebel group, the Lord's Resistance Army, and the central government.

24 Nov 2008

New model predicts risk of recurrence in early stage colon cancer patients

Researchers in the Duke Institute for Genome Sciences & Policy have developed a model for predicting risk of recurrence in early stage colon cancer patients, and have used the model to also predict sensitivity to chemotherapy and targeted therapy regimens.

24 Nov 2008

Gasping a good sign in sudden cardiac arrest

People who witness an individual collapse suddenly and unexpectedly should perform uninterrupted chest compressions even if the patient gasps or breathes in a funny way, research from the Resuscitation Research Group at The University of Arizona Sarver Heart Center shows.

24 Nov 2008

Sexual reproduction and evolution

The utility of sex, according to an intriguing new theory of evolutionary biology, may be its ability to promote genes that play well with many other partners rather than those that shine with just one specific set of genes.

24 Nov 2008

Tapentadol hydrochloride approved for pain relief

The U.S. Food and Drug Administration has approved Tapentadol hydrochloride, an immediate-release oral tablet for the relief of moderate to severe acute pain.

24 Nov 2008

Exercise helps manage anger in overweight children

Regular exercise seems to reduce anger expression in overweight but otherwise healthy children, researchers said.

24 Nov 2008

Gorillas may be at increased risk of pathogen exchange with humans

A new study finds that mountain gorillas are at increased risk of acquiring gastrointestinal microbes, such as Escherichia Coli, from humans.

24 Nov 2008

Artemisinin combination therapies may be almost as effective as treated bednets in preventing malaria

Artemisinin combination therapies (ACTs) could be almost as effective in reducing transmission of malaria as insecticide-treated bednets (ITNs) in areas of low transmission, a study based on data from Tanzania has found. In high transmission areas, long-acting antimalarial regimens may be needed to achieve significant transmission reductions.

24 Nov 2008

Children with sickle cell disease have inadequate healthcare

A new study finds that youth populations with sickle cell disease (SCD) are receiving inadequate healthcare, and thus may fail to benefit from scientific advances.

24 Nov 2008

Children with constipation a significant health issue

According to new research conducted at Nationwide Children's Hospital, the burden of illness in children suffering from constipation, and the costs associated with this condition, are roughly of the same magnitude as those for asthma and attention deficit-hyperactivity disorder (ADHD).

24 Nov 2008

Bioinformatics lecturers enlist undergrads to tackle DNA annotation challenge

In this week's issue of PLoS Biology, a team of Marseilles University lecturers led by Pascal Hingamp, describe the Annotathon - an innovative bioinformatics teaching approach that appeals to undergraduate biology students.

24 Nov 2008

Major discovery in the control of bad cholesterol

A study performed by the team of Dr. Nabil G. Seidah, Director of the Biochemical Neuroendocrinology Research Unit at the IRCM, shows for the very first time that the degradation by PCSK9 of the LDLR receptor, which is responsible for removing the bad cholesterol (LDL-cholesterol) from the bloodstream, may be inhibited by a third protein, annexin A2.

24 Nov 2008

New plan to tackle off-label prescribing

Physicians and policy-makers know that drugs are frequently prescribed to treat certain diseases despite a lack of FDA approval - a practice known as off-label prescribing.

24 Nov 2008