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Proteinuria reduction slows kidney decline in patients with focal segmental glomerulosclerosis

Reducing the amount of protein in the urine of patients with focal segmental glomerulosclerosis (FSGS), a rare disease in which scar tissue forms on the parts of the kidneys that filter waste from the blood, can significantly slow declines in kidney function and extend time before patients' kidneys fail, a new analysis by a Children's National Hospital researcher and her colleagues shows.

10 Aug 2020

Dietary interventions to optimize healing of injury-induced inflammation

Injuries induce the initiation of inflammation to control the damage. However, the resolution of the injury-induced inflammation leading to healing is not well characterized.

10 Aug 2020

Non-fasting blood test can help accurately identify youth at risk for diabetes and related risks

A simple blood test that does not require overnight fasting has been found to be an accurate screening tool for identifying youth at risk for type 2 diabetes and heart disease risk later in life, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

10 Aug 2020

Kids with silent malaria remain vulnerable to developing endemic Burkitt lymphoma

A study has found strong similarities between children with endemic Burkitt lymphoma — an aggressive cancer that attacks the body's defense system and children with silent malaria infection.

10 Aug 2020

Baylor Scott & White Research Institute enrolls first patients in NIH ACTIV-3 clinical trial

On Wednesday, August 5, in Dallas, just one day after the initiative was launched by the National Institutes of Health, Baylor Scott & White Research Institute enrolled the first patient in the world for the ACTIV-3 clinical trial. A second patient was enrolled the following day.

10 Aug 2020

AI-enhanced precision medicine approach lays groundwork for identification of autism subtype

A novel precision medicine approach enhanced by artificial intelligence (AI) has laid the groundwork for what could be the first biomedical screening and intervention tool for a subtype of autism, reports a new study from Northwestern University, Ben Gurion University, Harvard University and the Massachusetts Institute of Technology.

10 Aug 2020

Researchers develop fitness app to reduce hospital visits

An app that can measure fitness at home by hospital out-patients is being shared for free by its Malmö University developer. Such technology could be vital in reducing the number of appointments high risk groups must attend.

10 Aug 2020

Stress-induced activity in the brain region may predict chest pain in people with coronary artery disease

Stress-induced activity in the inferior frontal lobe of the brain may have a direct correlation with chest pain among people with coronary artery disease.

10 Aug 2020

TAU researchers reduce colorectal cancer metastases after tumor removal surgery

A research group from Tel Aviv University successfully reduced metastatic spread following tumor removal surgery in colorectal cancer patients.

10 Aug 2020

People may have a pre-existing immune response to COVID-19 thanks to common colds

Now, a new study shows that some people have immune responses against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, thanks to how the body reacted the last time it caught a cold. This means that even if a person has not been exposed to the novel coronavirus, the body has a memory of it and can trigger an immune response to fight the infection.

10 Aug 2020

Scientists identify new treatment targets for blinding retinal disease

When the eye isn't getting enough oxygen in the face of common conditions like premature birth or diabetes, it sets in motion a state of frenzied energy production that can ultimately result in blindness, and now scientists have identified new points where they may be able to calm the frenzy and instead enable recovery

10 Aug 2020

COVID-19 patient with repeatedly undetectable SARS-CoV-2 antibodies

A recent case study published in the Journal of Applied Laboratory Medicine in August 2020 illustrates this with its finding of persistent seronegativity in a patient confirmed to be SARS-CoV-2 positive.

10 Aug 2020

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

As COVID-19 continues to take a heavy toll on human health and life in many parts of the world, there is still no effective antiviral drug or vaccine. This has fueled an intensive search for small molecules and proteins that can inhibit viral entry and replication.

10 Aug 2020

A new feasible treatment option for vein of Galen aneurysmal malformation in babies

Endovascular treatment of vein of Galen aneurysmal malformation (VGAM) in babies with severe pulmonary hypertension can improve chances of survival, according to a study released today at the Society of NeuroInterventional Surgery's 17th Annual Meeting.

9 Aug 2020

FDA approves first companion diagnostic that uses liquid biopsy and NGS technology

Today, the U.S. Food and Drug Administration approved the first liquid biopsy companion diagnostic that also uses next-generation sequencing (NGS) technology to identify patients with specific types of mutations of the epidermal growth factor receptor (EGFR) gene in a deadly form of metastatic non-small cell lung cancer (NSCLC).

7 Aug 2020

Scientists find new way of identifying and targeting hidden HIV viral reservoirs during ART therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

7 Aug 2020

Research identifies a potential therapeutic target for clogged arteries

New work led by Carnegie's Meredith Wilson and Steve Farber identifies a potential therapeutic target for clogged arteries and other health risks that stem from an excess of harmful fats in the bloodstream. Their findings are published by PLOS Genetics.

7 Aug 2020

Blood News and Research

Proteinuria reduction slows kidney decline in patients with focal segmental glomerulosclerosis

Dietary interventions to optimize healing of injury-induced inflammation

Non-fasting blood test can help accurately identify youth at risk for diabetes and related risks

Kids with silent malaria remain vulnerable to developing endemic Burkitt lymphoma

Baylor Scott & White Research Institute enrolls first patients in NIH ACTIV-3 clinical trial

AI-enhanced precision medicine approach lays groundwork for identification of autism subtype

Researchers develop fitness app to reduce hospital visits

Stress-induced activity in the brain region may predict chest pain in people with coronary artery disease

TAU researchers reduce colorectal cancer metastases after tumor removal surgery

People may have a pre-existing immune response to COVID-19 thanks to common colds

Scientists identify new treatment targets for blinding retinal disease

COVID-19 patient with repeatedly undetectable SARS-CoV-2 antibodies

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

A new feasible treatment option for vein of Galen aneurysmal malformation in babies

FDA approves first companion diagnostic that uses liquid biopsy and NGS technology

Scientists find new way of identifying and targeting hidden HIV viral reservoirs during ART therapy

Research identifies a potential therapeutic target for clogged arteries

New approach enhances prediction of type 1 diabetes among susceptible children

Study shows link between high blood lead levels and aberrant methylation of DNA

USF Health researchers develop new reporter mouse strain for identifying P2X2-expressing cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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