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Combining medical knowledge to save lives

Cardiovascular disease (CVD) is the biggest killer among chronic diseases, claiming 17 million lives globally every year. Yet doctors can only attribute 50% of cardiovascular diseases to known risk factors.

9 Jul 2008

Gene silencer and quantum dots reduce protein production to a whisper

More than 15 years ago, scientists discovered a way to stop a particular gene in its tracks. The Nobel Prize-winning finding holds tantalizing promise for medical science, but so far it has been difficult to apply the technique, known as RNA interference, in living cells.

9 Jul 2008

Nanotechnology, biomolecules, and light unite to "cook" cancer cells

Using carbon nanotubes linked to tumor-homing antibodies, a research team headed by Ellen Vitetta, Ph.D., M.D., of the University of Texas Southwestern Medical Center has shown that they can specifically kill the targeted tumor cells using near-infrared light. This work appears in the Proceedings of the National Academy of Sciences.

9 Jul 2008

Holey nanoparticles create new tumor imaging and therapeutic agent

Using a polymer that has both water-soluble and water-insoluble regions, a team of investigators from the Siteman Center of Cancer Nanotechnology Excellence has created a nanoparticle shaped like a bialy, a close relative of the bagel. Combining this nanoparticle with manganese, a metal that boosts magnetic resonance imaging signals, and an antibody that targets blood vessels, the investigators then created a new type of imaging agent that also has the potential to deliver drugs to tumors.

9 Jul 2008

Nanoparticles detect telomerase activity

Telomerase, an enzyme that prevents chromosomes from shortening when they divide, is widely suspected of playing a key role in making cancer cells immortal.

9 Jul 2008

Nanocantilevers image nanoparticles in cells

Borrowing from a Nobel Prize-winning technique credited with starting the nanotechnology revolution, a team of researchers from Oak Ridge National Laboratory (ORNL) and Northwestern University's Nanomaterials for Cancer Diagnostics and Therapeutics has developed a method for imaging nanoparticles inside of cells.

9 Jul 2008

Improving quantum dot synthesis

Materials researchers at the National Institute of Standards and Technology (NIST) have developed a simplified, low-cost process for producing high-quality, water-soluble quantum dots for biomedical applications.

9 Jul 2008

New antimicrobial coatings from single-walled carbon nanotubes and lysozyme

A team of researchers in Auburn University's Samuel Ginn College of Engineering has produced new antimicrobial coatings with potential to prevent diseases from spreading on contaminated surfaces - possibly solving a growing problem not only in hospitals but also in schools, offices, airplanes and elsewhere.

9 Jul 2008

The good and bad side of dopamine

The chemical dopamine induces both desire and dread, according to new animal research in the July 9 issue of The Journal of Neuroscience. Although dopamine is well known to motivate animals and people to seek positive rewards, the study indicates that it also can promote negative feelings like fear.

9 Jul 2008

Slowing the biological processes of aging is way to prevent and fight diseases

A group of aging experts from the United States and the United Kingdom suggest that the best strategy for preventing and fighting a multitude of diseases is to focus on slowing the biological processes of aging.

9 Jul 2008

Enzymes are the way to a virus' 'heart'

The arrival of bluetongue virus (BTV) in the UK last year posed a major threat to the economy and the increasing temperatures of our changing climate mean it is here to stay.

9 Jul 2008

Liver protein fetuin-A linked to type 2 diabetes in seniors

The presence of a protein expressed by the liver which inhibits insulin action may identify individuals more likely to develop type 2 diabetes, according to a new study led by a researcher from the UCSD School of Medicine, to be published July 9 in the Journal of the American Medical Association.

9 Jul 2008

New tool identifies genes affecting health

A new tool which makes it possible to extract information about an individual's health from genotypes in a fraction of a second, has been developed by an academic at the University of Southampton.

9 Jul 2008

GAP method very accurate in predicting birth-weight of babies born to obese mothers

Researchers have found what they believe to be the most accurate way of predicting the birth-weight of babies born to the growing number of obese mothers, according to a study in the UK-based journal Ultrasound in Obstetrics and Gynecology.

9 Jul 2008

Fish oil supplements taken in last trimester could reduce risk of child developing asthma

Mothers who take fish oil supplements during the last trimester of their pregnancy could be reducing the risk of their child going on to develop asthma, claims a study published today (9th July) in the American Journal of Clinical Nutrition (Am J Clin Nutr 2008;88:167-175).

9 Jul 2008