Laboratory News and Research

RSS

Investigators identify gene that underlies devastating autoinflammatory condition in children

Investigators have identified a gene that underlies a very rare but devastating autoinflammatory condition in children. Several existing drugs have shown therapeutic potential in laboratory studies, and one is currently being studied in children with the disease, which the researchers named STING-associated vasculopathy with onset in infancy (SAVI).

17 Jul 2014

Single injection of protein FGF1 enough to restore blood sugar levels

In mice with diet-induced diabetes—the equivalent of type 2 diabetes in humans—a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days.

17 Jul 2014

Scientists build artificial cells programmed to eat their undesirable neighbors

A team of researchers has devised a Pac-Man-style power pellet that gets normally mild-mannered cells to gobble up their undesirable neighbors. The development may point the way to therapies that enlist patients’ own cells to better fend off infection and even cancer, the researchers say. A description of the work will be published July 15 in the journal Science Signaling.

16 Jul 2014

Thirteen scientists receive grant to identify new treatments, cure for psoriasis

Thirteen scientists received a total of $1.05 million in funding from the National Psoriasis Foundation for projects that aim to identify new treatments and a cure for psoriasis—an autoimmune disease that appears on the skin, affecting 7.5 million Americans—and psoriatic arthritis—an inflammatory arthritis that affects the joints and tendons, occurring in up to 30 percent of people with psoriasis.

16 Jul 2014

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

The basic idea of cancer chemoprevention is to arrest or reverse the progression of premalignant cells towards full malignancy, using physiological mechanisms that do not kill healthy cells.

16 Jul 2014

Research highlights potential cancer risk in non-smokers

Research led by the University of York has highlighted the potential cancer risk in non-smokers - particularly young children - of tobacco smoke gases and particles deposited to surfaces and dust in the home.

16 Jul 2014

USAMRIID provides on-site laboratory support to current Ebola outbreak

Analysis of clinical samples from suspected Lassa fever cases in Sierra Leone showed that about two-thirds of the patients had been exposed to other emerging diseases, and nearly nine percent tested positive for Ebola virus.

16 Jul 2014

Research sheds new light on brain's complicated barrier tissue

Research from the University of Copenhagen is shedding new light on the brain's complicated barrier tissue. The blood-brain barrier is an effective barrier which protects the brain, but which at the same time makes it difficult to treat diseases such as Alzheimer's.

16 Jul 2014

Engineering single-celled parasite in cat's intestine as cancer vaccine

Toxoplasma gondii (T. gondii) is a single-celled parasite that is happiest in a cat's intestines, but it can live in any warm blooded animal. Found worldwide, T. gondii affects about one-third of the world's population, 60 million of which are Americans.

16 Jul 2014

Personalized medicine for breast cancer patients may be just around the corner

For breast cancer patients, the era of personalized medicine may be just around the corner, thanks to recent advances by USC Stem Cell researcher Min Yu and scientists at Massachusetts General Hospital and Harvard Medical School.

16 Jul 2014

OSU creates new assay to test authenticity of primary drugs used to treat malaria

Chemists and students in science and engineering at Oregon State University have created a new type of chemical test, or assay, that's inexpensive, simple, and can tell whether or not one of the primary drugs being used to treat malaria is genuine - an enormous and deadly problem in the developing world.

16 Jul 2014

CHEST guideline released for PAH

An updated CHEST guideline for treating pulmonary arterial hypertension provides some evidence-based recommendations but also highlights many evidence gaps.

15 Jul 2014

Study to understand impairments of working memory among patients with schizophrenia

The inability to ignore irrelevant stimuli underlies the impaired working memory and cognition often experienced by individuals diagnosed with schizophrenia, reports a new study in the current issue of Biological Psychiatry.

15 Jul 2014

DARPins could revolutionize protein therapeutics

Integrating an INTEGRA VIAFLO 96 multichannel pipette into their high throughput expression facility has enabled Molecular Partners (Zurich, Switzerland) to streamline the discovery and development of a novel class of targeted protein therapeutics termed DARPins.

From INTEGRA Biosciences 15 Jul 2014

BAI and Novartis determine whether investigational drugs can prevent symptoms of Alzheimer's

Researchers from the Banner Alzheimer's Institute (BAI) today announced a partnership with Novartis in a pioneering medical trial to determine whether two investigational anti-amyloid drugs-an active immunotherapy and an oral medication-can prevent or delay the emergence of symptoms of Alzheimer's in people at particularly high risk for developing the disease at older ages.

15 Jul 2014

CDC closes labs after anthrax, flu accidents

Federal government labs in Atlanta were temporarily shut after it was discovered they had improperly sent potentially deadly pathogens, including anthrax, botulism and virulent bird flue virus, to other labs.

15 Jul 2014

Researchers create combination drug that controls both tumor growth and metastasis

Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase (sEH) inhibitor, the drug controls angiogenesis (blood vessel formation), limiting a tumor's ability to grow and spread.

14 Jul 2014

Laboratory News and Research

Investigators identify gene that underlies devastating autoinflammatory condition in children

Single injection of protein FGF1 enough to restore blood sugar levels

Scientists build artificial cells programmed to eat their undesirable neighbors

Thirteen scientists receive grant to identify new treatments, cure for psoriasis

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

Research highlights potential cancer risk in non-smokers

USAMRIID provides on-site laboratory support to current Ebola outbreak

Research sheds new light on brain's complicated barrier tissue

Engineering single-celled parasite in cat's intestine as cancer vaccine

Personalized medicine for breast cancer patients may be just around the corner

OSU creates new assay to test authenticity of primary drugs used to treat malaria

CHEST guideline released for PAH

Study to understand impairments of working memory among patients with schizophrenia

DARPins could revolutionize protein therapeutics

BAI and Novartis determine whether investigational drugs can prevent symptoms of Alzheimer's

CDC closes labs after anthrax, flu accidents

Researchers create combination drug that controls both tumor growth and metastasis

Boston Scientific gains CE Mark, begins European commercial launch of 25 mm Lotus TAVI System

New research opens up potential new therapeutic targets for hard-to-treat food allergy

First Edition: July 14, 2014

Lab Diagnostics and Automation - Third Edition eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics