CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

ISSCR updates guidelines for oversight and regulation of stem cell-based embryo models

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid advancements and ensure responsible scientific progress.

11 Jun 2025

Italian researcher sheds light on the lasting psychiatric impact of childhood trauma

In a revealing Genomic Press Interview published today in Brain Medicine, Sara Poletti, PhD, senior researcher at IRCCS Ospedale San Raffaele Milan, illuminates the profound connections between childhood adversity and lifelong vulnerability to psychiatric disorders through persistent neuroinflammation pathways and alterations in brain structure.

11 Jun 2025

Study aims to demystify the immune toxicity triggered by osimertinib-ICI co-treatment

Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases and remains a leading cause of cancer mortality worldwide.

6 Jun 2025

Two blood pressure management strategies yield similar cognitive outcomes after non-cardiac surgery

A large international study has found that two different approaches to managing blood pressure in older adults undergoing non-cardiac surgery, one avoiding low blood pressure (hypotension) and the other high blood pressure (hypertension), lead to similar outcomes in terms of in-hospital delirium and cognitive changes one year after surgery.

4 Jun 2025

Microfluidic contact lenses emerge as next generation tools for eye care

The tear film coating the eye offers a window into a person's systemic and ocular health, carrying biomarkers such as glucose, electrolytes, and proteins.

31 May 2025

Monash-led research highlights urgent need to redefine PCOS

Most experts and those experiencing the potentially debilitating features of Polycystic Ovary Syndrome (PCOS), which affects one in eight women, want greater awareness and a name change to improve care and outcomes.

29 May 2025

Traditional Kava rituals provide alternative pathway to PTSD recovery

Researchers reviewed pilot and qualitative evidence suggesting that combining traditional Pacific kava with talanoa dialogue may help reduce PTSD symptoms among Pacific veterans and first responders. A clinical trial is planned to formally evaluate the safety, efficacy, and cultural adaptability of this innovative, culturally grounded therapy.

29 May 2025

ESMO releases updated scale to measure clinical benefit of cancer treatments

The European Society for Medical Oncology (ESMO) is pleased to announce the publication of the latest version of the scale that measures the clinical benefit of cancer treatments, the ESMO-MCBS (ESMO-Magnitude of Clinical Benefit Scale).

23 May 2025

New genetic test speeds up brain tumor diagnosis to just two hours

Scientists and medics have developed an ultra-rapid method of genetically diagnosing brain tumors that will cut the time it takes to classify them from 6-8 weeks, to as little as two hours – which could improve care for thousands of patients each year in the UK.

21 May 2025

Allen Institute introduces CellScapes to map cellular cooperation

The Allen Institute today announced the launch of CellScapes, a bold new research initiative aimed at revolutionizing how scientists understand and predict the behavior of human cells as they work together to build tissues and organs.

15 May 2025

Brain imaging study reveals the power of 'eureka moments'

Have you ever been stuck on a problem, puzzling over something for what felt like ages without getting anywhere, but then suddenly the answer came to you like a bolt from the blue?

15 May 2025

Can diet ease IBS? A low-FODMAP plan cut symptoms but raised nutrient concerns

A 10-week low-FODMAP diet significantly reduced symptom severity in Saudi adults with IBS, with most shifting from severe to moderate symptoms. However, the restrictive diet also led to declines in several essential nutrients, highlighting the need for professional guidance.

14 May 2025

Readers scrutinize federal cuts and medical debt

The recent KFF Health News article "Beyond Ivy League, RFK Jr.'s NIH Slashed Science Funding Across States That Backed Trump" (April 17) struck a nerve.

13 May 2025

A California lawmaker leans into her medical training in fight for health safety net

State Sen. Akilah Weber Pierson anticipates that California's sprawling Medicaid program, known as Medi-Cal, may need to be dialed back after Gov. Gavin Newsom releases his latest budget, which could reflect a multibillion-dollar deficit.

9 May 2025

Covered California pushes for better health care as federal spending cuts loom

Faced with potential federal spending cuts that threaten health coverage and falling childhood vaccination rates, Monica Soni, the chief medical officer of Covered California, has a lot on her plate — and on her mind.

2 May 2025

Intimate relationships may shield against cognitive decline during chemo

A satisfying intimate relationship may help diminish chemotherapy-related cognitive problems experienced by patients with breast cancer, a new study suggests.

29 Apr 2025

Heart transplant volume rises with adoption of DCD techniques

Researchers at the Annual Meeting and Scientific Sessions of the International Society of Heart and Lung Transplantation (ISHLT) marked the 10-year anniversary of modern heart donation after circulatory death (DCD), a technique that has significantly increased transplant volumes around the world.

27 Apr 2025