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Alarming increase in obesity-related cancers among young people in China

Obesity-related cancer rates in China were rising at an alarming 3.6% every year between 2007 and 2021 while non-obesity-related cancers remained stable, according to the first comprehensive study published August 22 in the Cell Press journal Med.

23 Aug 2024

Exploring the impact of thyroid hormone on brain function

Thyroid hormone plays a key role in regulating a range of physiologic functions, including metabolism, temperature, heart rate, and growth. It accomplishes this impressive array of activities by interacting with almost every organ system in the body. Yet despite a long history of research on how thyroid hormone influences different organs, its effects on arguably the most crucial organ - the brain - have remained shrouded in mystery.

23 Aug 2024

New perspectives on targeting BRAF alterations in cancer

A new research perspective was published in Oncotarget's Volume 15 on July 16, 2024, entitled, "Targeting the multifaceted BRAF in cancer: New directions."

12 Aug 2024

Potential liver risks from popular herbal supplements revealed in new study

A study in JAMA Network Open reveals that 5% of U.S. adults consume six potentially hepatotoxic botanicals, highlighting a significant need for increased regulatory oversight.

6 Aug 2024

New compound ZTA-26 could be a game-changer in lipid metabolism regulation

Scientists at Nagoya University in Japan have made a significant breakthrough in treating lipid disorders.

6 Aug 2024

Rising cancer rates in younger generations signal urgent need for early-life prevention strategies

A study in The Lancet Public Health reveals rising cancer incidence and mortality among younger US birth cohorts, indicating increased early-life carcinogenic exposure.

4 Aug 2024

Study finds fourfold increase in risk of overt hypothyroidism after diagnosis of gestational subclinical hypothyroidism

A new study has shown that subclinical hypothyroidism diagnosed before 21 weeks of pregnancy is associated with more than fourfold higher rates of overt hypothyroidism or thyroid replacement therapy within 5 years of delivery.

2 Aug 2024

Decreasing folate intake can support healthier metabolisms in aging animal models

In a study published in Life Science Alliance, Texas A&M AgriLife Research scientists found that decreasing folate intake can support healthier metabolisms in aging animal models, challenging the conventional belief that high folate consumption universally benefits health.

2 Aug 2024

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Xueqing Hu , Ujjwol Khatri , Tao Shen , and Jie Wu, at University of Oklahoma Health Sciences Center, USA, provides a comprehensive review of the role of the RET (REarranged during Transfection) receptor tyrosine kinase in cancer development and the advancements in RET-targeted cancer therapies.

19 Jul 2024

An Arm and a Leg: The woman who beat an $8,000 hospital fee

Hospital facility fees. They can feel like a charge just for walking in the door. Hospitals say they go toward overhead on facilities with lots of specialized equipment and staff, like emergency rooms.

17 Jul 2024

deCODE genetics study highlights potential drug targets for autoimmune thyroid disease

Scientists at deCODE genetics, a subsidiary of Amgen, have published a study in Nature Communications, comparing over 110 thousand patients with autoimmune thyroid disease (AITD) from Iceland, Finland, UK and USA with 1,1 million controls.

11 Jul 2024

Blood cancer drug could help improve the efficiency of radiotherapy in meningiomas

Drugs developed to fight blood and other cancers could also help improve the efficiency of radiotherapy in the most commonly diagnosed low-grade brain tumour in adults, a new study has found.

10 Jul 2024

Pregnancy loss risk heightened by family history of endocrine diseases

Women who have close family members with endocrine diseases, including type 2 diabetes, thyroid diseases and polycystic ovary syndrome (PCOS), are at higher risk of pregnancy loss, a new study has found.

9 Jul 2024

Mayo Clinic makes medical history with total larynx transplant for cancer patient

Mayo Clinic announces a groundbreaking achievement in organ transplantation, offering hope to thousands who have lost their ability to speak, swallow and breathe on their own due to diminished function or loss of their larynx.

9 Jul 2024

GLP-1 drugs found to lower cancer risk in diabetes patients

Research finds that GLP-1 receptor agonists significantly reduce the risk of 10 out of 13 obesity-associated cancers in type 2 diabetes patients compared to insulins, but show varied results against metformin.

8 Jul 2024

Novel genetic predisposition to being overweight or obese identified

Researchers performed a case-control study to compare metabolic changes between individuals homozygous for a loss-of-function genetic variation in small integral membrane protein 1 (SMIM1) and the general population.

25 Jun 2024

Vitamin D for carpal tunnel syndrome symptoms

Study examines the impact of vitamin D supplementation on carpal tunnel syndrome (CTS) patients with low vitamin D levels, finding that it improves pain relief and symptom severity when added to corticosteroid therapy.

23 Jun 2024

Role of SMIM1 gene in obesity uncovered

Scientists have discovered a new cause of why people who lack a specific blood group are genetically predisposed to be overweight or obese.

20 Jun 2024

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

A genetic treatment targeting the causal NRAS c.181C>A mutation in congenital melanocytic naevus.

19 Jun 2024

Study reveals doubling of chronic hypertension in pregnancy from 2008 to 2021 in the U. S.

The number of individuals in the U.S. who had chronic hypertension or chronic high blood pressure during pregnancy doubled between 2008 and 2021, while the prescribing and filling of antihypertensive medication during pregnancy remained low but stable at 60%, according to new research published today in Hypertension, a peer-reviewed journal of the American Heart Association.

17 Jun 2024