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Using lung simulators to help tackle COVID-19

COVID-19 is a virus that affects the respiratory system in humans. By using realistic lung simulators, we can understand how this virus affects the lungs.

From neosim AG 1 Jun 2020

Findings indicate potential therapeutic interventions for Alzheimer’s and other diseases

A team of scientists from Japan recently achieved more efficient degradation of the human serum albumin protein - an important protein in the blood - via high-intensity infrared irradiation, by attaching a zinc metal complex to the protein.

1 Jun 2020

Researchers develop new method to measure hydroxychloroquine levels in SLE patients

Researchers at Uppsala University and Uppsala University Hospital have developed a new method to measure levels of the medication hydroxychloroquine in patients with rheumatic disease systemic lupus erythematosus (SLE).

1 Jun 2020

Researchers use optical mapping system to observe the effect of hydroxychloroquine

The malaria drug hydroxychloroquine, which has been promoted as a potential treatment for Covid-19, is known to have potentially serious effects on heart rhythms.

1 Jun 2020

No specific COVID-19-linked lesions found despite extensive organ injury

A recent paper published online on the preprint server medRxiv in May 2020 reports autopsy results on COVID-19 patients. The paper concludes that there were no specific hallmark lesions of COVID-19 in any of the many organs found to be injured by the infection in patients who died of the disease.

1 Jun 2020

How COVID-19 affects the nervous system

A new paper published in the journal JAMA Neurology in May 2020 discusses the presentation and complications of COVID-19 with respect to the nervous system.

31 May 2020

Deep vein clots in critical COVID-19 illness

A new research paper published in the journal JAMA Network Open in May 2020 reports a high incidence of deep vein clots in patients with severe COVID-19 at a single French medical center. This could indicate the need for systematic anticoagulant therapy in these patients as a preventive measure.

31 May 2020

COVID-19 mortality is significantly higher in hospitalized patients with diabetes

A new meta-analysis published on the preprint server medRxiv by the researchers from the United States and Greece reveals that the likelihood of death is 65% higher in hospitalized coronavirus disease (COVID-19) patients with diabetes when compared to non-diabetics – urging the adequate glucose control in the era of the pandemic.

31 May 2020

University of Freiburg receives 30 million euros for excellent research

The German Research Foundation has approved a new proposal for a collaborative research center under the leadership of the Institute for Experimental Cardiovascular Medicine at the University Heart Centre Freiburg · Bad Krozingen.

30 May 2020

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

A large international trial involving UCL and University College London Hospitals NHS Foundation Trust (UCLH) has found that pembrolizumab, a form of immunotherapy, more than doubled the 'progression free survival' time of patients with a specific subtype of advanced bowel cancer, when compared with chemotherapy.

30 May 2020

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

By analyzing tumors from patients treated with immunotherapy for advanced kidney cancer in three clinical trials, Dana-Farber Cancer Institute scientists have identified several features of the tumors that influence their response to immune checkpoint inhibitor drugs.

30 May 2020

Preventing novel coronavirus from entering into a host cell

How might the novel coronavirus be prevented from entering a host cell in an effort to thwart infection? A team of biomedical scientists has made a discovery that points to a solution.

30 May 2020

Columbia engineers develop novel technique to study how tissues flow in the embryo

As embryos develop, tissues flow and reorganize dramatically on timescales as brief as minutes. This reorganization includes epithelial tissues that cover outer surfaces and inner linings of organs and blood vessels.

30 May 2020

Identifying optimal vasopressor treatment for nontraumatic subarachnoid hemorrhage

Results of an Electronic Health Record (EHR) study assessing the most commonly used medications for raising blood pressure in patients with nontraumatic subarachnoid hemorrhage (SAH), a rare type of stroke, have been published in Neurosurgical Focus by scientists at The University of Texas Health Science Center at Houston (UTHealth).

30 May 2020

High-throughput analysis of blood plasma could help identify biomarkers for ALS

High-throughput analysis of blood plasma could aid in identification of diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis (ALS), according to research from North Carolina State University.

29 May 2020

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

UMSOM scientists develop experimental rapid diagnostic test for COVID-19

Scientists from the University of Maryland School of Medicine (UMSOM) developed an experimental diagnostic test for COVID-19 that can visually detect the presence of the virus in 10 minutes.

29 May 2020

Cancer drug nilotinib found to be safe and well-tolerated in Alzheimer's disease clinical trial

A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer's disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy.

29 May 2020

Using gene therapy to help the body to make its own cancer drugs

Imagine that we could instruct our bodies to make the drugs they need themselves. The gene technology that makes this possible is called mRNA therapy, which may become a major tool in the treatment of multiple diseases.

29 May 2020

NIH funding supports research on first therapeutic drug to regenerate heart tissue

With funding from the National Institutes of Health, University of Arkansas researchers hope to develop the first therapeutic drug that can regenerate heart tissue.

29 May 2020

Blood News and Research

Using lung simulators to help tackle COVID-19

Findings indicate potential therapeutic interventions for Alzheimer’s and other diseases

Researchers develop new method to measure hydroxychloroquine levels in SLE patients

Researchers use optical mapping system to observe the effect of hydroxychloroquine

No specific COVID-19-linked lesions found despite extensive organ injury

How COVID-19 affects the nervous system

Deep vein clots in critical COVID-19 illness

COVID-19 mortality is significantly higher in hospitalized patients with diabetes

University of Freiburg receives 30 million euros for excellent research

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

Preventing novel coronavirus from entering into a host cell

Columbia engineers develop novel technique to study how tissues flow in the embryo

Identifying optimal vasopressor treatment for nontraumatic subarachnoid hemorrhage

High-throughput analysis of blood plasma could help identify biomarkers for ALS

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

UMSOM scientists develop experimental rapid diagnostic test for COVID-19

Cancer drug nilotinib found to be safe and well-tolerated in Alzheimer's disease clinical trial

Using gene therapy to help the body to make its own cancer drugs

NIH funding supports research on first therapeutic drug to regenerate heart tissue

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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