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Gene therapy can reduce painful bleeding episodes in patients with hemophilia B

Symptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the U.K.

12 Dec 2011

MCC invests $122M in Lesotho health system to address key challenges, including HIV, TB

"The Millennium Challenge Corporation (MCC), through its partnership with the Millennium Challenge Account-Lesotho, is helping Lesotho address key challenges in its health sector through a $122 million investment in health infrastructure and health systems," IIP Digital reports.

9 Dec 2011

New pediatric formula for Chagas disease treatment developed in Brazil

"A new pediatric formulation developed in Brazil holds out hope for a cure for over 90 percent of newborn babies infected with Chagas disease, a parasitic infection endemic in 21 Latin American countries, where it kills more people every year than malaria," Inter Press Service reports.

9 Dec 2011

Study explains molecular basis for cherubism disease

The Samuel Lunenfeld Research Institute's Drs. Frank Sicheri, Tony Pawson and Sebastian Guettler, in collaboration with Dr. Robert Rottapel at the Ontario Cancer Institute, have uncovered the detailed architecture of a crucial component of Tankyrase, a protein linked to the bone development disorder cherubism and involved in a myriad of cellular processes.

9 Dec 2011

Experimental sublingual vaccine shows promise against influenza infection

Scientists from the International Vaccine Institute (IVI) have discovered that an antigen common to most influenza viruses, and commonly referred to as matrix protein 2 (M2), when administered under the tongue could protect mice against experimental infection caused by various influenza viruses, including the highly pathogenic avian H5 virus and the pandemic H1 ("swine flu") virus.

9 Dec 2011

Study may help personalize pain medication management for sickle cell disease patients

A study that may help personalize pain medication management for sickle cell disease patients is underway at Georgia Health Sciences University.

9 Dec 2011

Genetically identical Salmonella appear in 2 types, each with an infective advantage

An unusual regulatory mechanism that controls the swimmer/non-swimmer option in genetically identical Salmonella also impacts the bacteria's ability to cause infection.

9 Dec 2011

Study: Hearing and sight are deeply intertwined

Our senses of sight and hearing work closely together, perhaps more than people realize, a new UCLA psychology study shows.

9 Dec 2011

Positive results from Metabolex arhalofenate plus febuxostat study on hyperuricemia, gout

Metabolex announced positive results from its clinical study of arhalofenate in combination with febuxostat. A key goal in the treatment of gout is to address the patient's underlying hyperuricemia by treatment with drugs that lower serum uric acid.

9 Dec 2011

Mystery of unpleasant tough texture in vegetable oil-cooked hot dogs

In part of an effort to replace animal fat in hot dogs, sausages, hamburgers and other foods with healthier fat, scientists are reporting an advance in solving the mystery of why hot dogs develop an unpleasant tough texture when vegetable oils pinch hit for animal fat. A report on their study appears in ACS' Journal of Agricultural and Food Chemistry.

8 Dec 2011

Recommendations to address challenges associated with chronic inflammatory diseases

A dramatic increase in the incidence of chronic inflammatory diseases such as asthma, allergy, and irritable bowel syndrome, has led to concern about how modern lifestyles may trigger physiological defense mechanisms.

8 Dec 2011

Considering varying extent to which genes are turned on or off can help develop personalised, predictive medicines

The vast majority of genetic disorders (schizophrenia or breast cancer, for example) have different effects in different people. Moreover, an individual carrying certain mutations can develop a disease, whereas another one with the same mutations may not. This holds true even when comparing two identical twins who have identical genomes. But why does the same mutation have different effects in different individuals?

8 Dec 2011

Ixabepilone-sunitinib combination holds potential against chemotherapy-resistant ovarian cancer

The use of two drugs never tried in combination before in ovarian cancer resulted in a 70 percent destruction of cancer cells already resistant to commonly used chemotherapy agents, say researchers at Mayo Clinic in Florida.

8 Dec 2011

Two new research studies to help colicky infant and their parents

The wail of a colicky baby can send parents into near panic and cause sleepless nights for all. Now, two innovative research studies are being conducted at the new UT Physicians Colic Clinic at The University of Texas Health Science Center at Houston (UTHealth) to help both crying babies and their worried parents.

8 Dec 2011

New gene editing technique can heal sickle cell patients with their own cells

Researchers at the Salk Institute for Biological Studies have developed a way to use patients' own cells to potentially cure sickle cell disease and many other disorders caused by mutations in a gene that helps produce blood hemoglobin.

8 Dec 2011

Scientists discover genetic trigger that makes stem cells differentiate in nose epithelia

University of California, Berkeley, neuroscientists have discovered a genetic trigger that makes the nose renew its smell sensors, providing hope for new therapies for people who have lost their sense of smell due to trauma or old age.

8 Dec 2011

BCX4945 proves effective at clearing malaria infections

An antimalarial agent developed by researchers at Albert Einstein College of Medicine of Yeshiva University proved effective at clearing infections caused by the malaria parasite most lethal to humans - by literally starving the parasites to death. The novel research, carried out on a small number of non-human primates, could bolster efforts to develop more potent therapies against one of the world's leading killers.

8 Dec 2011

PrEP shows promise against HIV infection

A new weapon has emerged to prevent HIV infection. Called pre-exposure prophylaxis, or PrEP, it is a strategy of providing medications to at-risk people before they are exposed to the virus. Having shown great promise in recent phase 3 clinical trials, PrEP may soon be rolled out for public use.

8 Dec 2011

OUP announces acquisition of two journal titles from Preston Publications

Oxford University Press (OUP) is pleased to announce the acquisition of two titles, Journal of Analytical Toxicology (JAT) and Journal of Chromatographic Science (JCS), from Preston Publications, in a transaction managed by DeSilva+Phillips.

8 Dec 2011

Alzheimer’s vaccine cures memory of mice

A vaccine that slows the progression of Alzheimer’s disease and other types of dementia has been developed by researchers at the University of Sydney’s Brain and Mind Research Institute (BMRI).

7 Dec 2011

Laboratory News and Research

Gene therapy can reduce painful bleeding episodes in patients with hemophilia B

MCC invests $122M in Lesotho health system to address key challenges, including HIV, TB

New pediatric formula for Chagas disease treatment developed in Brazil

Study explains molecular basis for cherubism disease

Experimental sublingual vaccine shows promise against influenza infection

Study may help personalize pain medication management for sickle cell disease patients

Genetically identical Salmonella appear in 2 types, each with an infective advantage

Study: Hearing and sight are deeply intertwined

Positive results from Metabolex arhalofenate plus febuxostat study on hyperuricemia, gout

Mystery of unpleasant tough texture in vegetable oil-cooked hot dogs

Recommendations to address challenges associated with chronic inflammatory diseases

Considering varying extent to which genes are turned on or off can help develop personalised, predictive medicines

Ixabepilone-sunitinib combination holds potential against chemotherapy-resistant ovarian cancer

Two new research studies to help colicky infant and their parents

New gene editing technique can heal sickle cell patients with their own cells

Scientists discover genetic trigger that makes stem cells differentiate in nose epithelia

BCX4945 proves effective at clearing malaria infections

PrEP shows promise against HIV infection

OUP announces acquisition of two journal titles from Preston Publications

Alzheimer’s vaccine cures memory of mice

Lab Diagnostics and Automation - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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