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Influence of employment during COVID-19 on cognitive and motor functions among elders

The effects of employment on geriatric health during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak.

1 Nov 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

How next-gen sequencing is changing antibody drug discovery

New study outlines how next-generation sequencing (NGS) and machine-learning methods can revolutionize antibody discovery, particularly against SARS-CoV-2. The research demonstrates that NGS provides greater epitopic and paratopic diversity, enabling more effective identification and prioritization of therapeutic antibodies.

31 Oct 2023

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

Understanding COVID-19 mortality in people with severe mental illness and different ethnicities

In a recent study published in the British Journal of Psychiatry, researchers evaluated mortality in individuals with severe mental illness (SMI) following COVID-19.

31 Oct 2023

COVID-19’s long reach: Some physical symptoms can persist up to two years post-diagnosis

Researchers investigated the prevalence rate of physical-type symptoms by the severity of acute COVID-19 beyond two years of diagnosis.

31 Oct 2023

Late nights and skipping breakfast linked to increased heart disease risk, especially in men

Late sleepers who skip breakfast face elevated risk for metabolic syndrome and cardiovascular disease, especially in men, according to a large-scale study. The effects vary by age and gender, pointing to the complex interactions between sleep patterns, eating habits, and heart health.

30 Oct 2023

New MECP2 gene variant identified and characterized in Rett syndrome

Rett syndrome is a rare devastating neurological disorder that primarily affects young girls and manifests as an impaired ability to walk and talk, along with characteristic 'hand-wringing' movements, seizures, and cognitive disability.

30 Oct 2023

New classification criteria for antiphospholipid syndrome

APS is a systemic autoimmune disease associated with persistent antiphospholipid antibodies (aPL). It can cause thrombosis and pregnancy complications as well as non-thrombotic manifestations such as cardiac valve disease.

30 Oct 2023

Human-to-lion COVID transmission confirmed: Singapore study rings alarm bells for endangered species

The study reveals that the SARS-CoV-2 delta variant was transmitted from humans to lions at a Singapore zoo, emphasizing the risk to captive and endangered animals. The researchers call for strict infection control measures and suggest vaccinations for susceptible animals to protect them from anthropogenic viral transmissions.

30 Oct 2023

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

The efficacy of the bivalent Pfizer-BioNTech COVID-19 messenger ribonucleic acid (mRNA) vaccine BNT162b2 BA.4/5.

30 Oct 2023

Does adding sigh breaths to the usual care of trauma patients receiving mechanical ventilation increase ventilator-free days?

Researchers investigated whether adding sigh breaths to standard care regimens of mechanically ventilated trauma patients increased ventilator-free days.

30 Oct 2023

Trauma-informed care training leads to significant gains in knowledge and organizational change

A McLean Hospital study of 598 people across various industries who underwent a two-day training workshop where they learned about trauma-informed care and how to deploy these skills within their organizations, found participants reported significant gains in knowledge of trauma and made improvements to organizational policies, according to a comparison of survey data collected before and after the trainings.

30 Oct 2023

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

The role of anti-SARS-CoV-2 antibody levels on COVID-19 outcomes in patients with T2D.

30 Oct 2023

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

Researchers found that SARS-CoV-2 antigens can persist in the body for up to 14 months after initial infection, challenging the idea that COVID-19 is a transient illness. This finding has implications for understanding long-term effects of the virus and could influence future treatments and vaccines.

30 Oct 2023

Current jargon on antibiotic resistance fails to stick or scare, study finds

Researchers find that current terminology related to antimicrobial resistance (AMR) fails to effectively communicate the risks to the public. The study reveals that terms like "AMR" and "antimicrobial resistance" are poorly remembered and do not evoke sufficient risk perception, highlighting the need for improved public health messaging.

29 Oct 2023

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

Canadian researchers develop a cell-free DNA-based multimodal assay for early cancer detection in patients with Li-Fraumeni Syndrome, a high-cancer-risk condition. The assay outperforms conventional methods, promising more sensitive and less invasive cancer surveillance.

29 Oct 2023

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

AbbVie today announced that the UK Medicines and Healthcare products Regulatory Agency has granted conditional Marketing Authorisation for Tepkinly® (epcoritamab) as a monotherapy for the treatment of adults with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), after two or more systemic therapies.

28 Oct 2023

Ethical microbiome research with Indigenous communities: A framework for collaboration and sovereignty

Research on the trillions of microorganisms that make up a person's microbiome can lead to medical breakthroughs to treat diseases like inflammatory bowel syndrome and diabetes.

27 Oct 2023

From education to politics: a pan-European analysis of COVID-19 conspiracy theory influences

People’s belief in COVID-19-related conspiracy theories (CTs) In Europe.

27 Oct 2023

Syndrome News and Research

Influence of employment during COVID-19 on cognitive and motor functions among elders

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

How next-gen sequencing is changing antibody drug discovery

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

Understanding COVID-19 mortality in people with severe mental illness and different ethnicities

COVID-19’s long reach: Some physical symptoms can persist up to two years post-diagnosis

Late nights and skipping breakfast linked to increased heart disease risk, especially in men

New MECP2 gene variant identified and characterized in Rett syndrome

New classification criteria for antiphospholipid syndrome

Human-to-lion COVID transmission confirmed: Singapore study rings alarm bells for endangered species

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

Does adding sigh breaths to the usual care of trauma patients receiving mechanical ventilation increase ventilator-free days?

Trauma-informed care training leads to significant gains in knowledge and organizational change

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

Current jargon on antibiotic resistance fails to stick or scare, study finds

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

Ethical microbiome research with Indigenous communities: A framework for collaboration and sovereignty

From education to politics: a pan-European analysis of COVID-19 conspiracy theory influences

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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