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Clinical study shows promising results for treatment of VHL disease-associated renal tumors

In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)–associated renal cell carcinoma.

28 May 2020

Type 2 diabetes is more prevalent in American Indians and Alaska Natives

Type 2 diabetes (T2D) affects American Indians and Alaska Natives at approximately three times the rate of white Americans and is closely linked to the disproportionately high rates of cardiovascular diseases such as heart attacks and strokes, according to the American Heart Association Scientific Statement "Cardiovascular Health in American Indians and Alaska Natives," published today in the Association's flagship journal Circulation.

28 May 2020

PKU-led team identifies potent neutralizing antibodies against SARS-CoV-2

A joint research team led by Sunney Xie, Director of Beijing Advanced Innovation Center for Genomics at Peking University has successfully identified multiple highly potent neutralizing antibodies against the novel coronavirus SARS-CoV-2, the causative virus of the respiratory disease COVID-19, from convalescent plasma by high-throughput single-cell sequencing.

28 May 2020

Antibody tests were hailed as way to end lockdowns. Instead, they cause confusion.

Aspen was an early COVID-19 hot spot in Colorado, with a cluster of cases in March linked to tourists visiting for its world-famous skiing. Tests were in short supply, making it difficult to know how the virus was spreading.

28 May 2020

Molecular signatures can predict outcome of sepsis patients based on their immune response

Scientists have identified molecular signatures in the immune component of the blood which indicate how patients in intensive care with sepsis, septic shock and systemic inflammatory response syndrome are likely to respond to the conditions.

28 May 2020

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

Thermo Fisher Scientific, the world leader in serving science, and Biognosys, a leading developer of next-generation proteomics solutions, announce they are continuing their collaboration to advance data independent acquisition mass spectrometry-based workflows.

From Thermo Fisher Scientific Inc. 28 May 2020

Clinical trial of COVID-19 vaccine starts in Australia

Over 100 candidate vaccines are being explored as a means of ending the COVID-19 pandemic. Eight of these have already made it to clinical trials in humans, and another 94 are in the pre-clinical evaluation stage.

27 May 2020

WVU partnership produces thousands of swabs to meet demands for COVID-19 testing

With significantly increased testing a key component in the battle against COVID-19, the Innovation Hub at West Virginia University is working with WVU Medicine to churn out up to 10,000 swabs weekly to meet demands for tests.

27 May 2020

Research provides new evidence for potential blood-based biomarker for Alzheimer's

A potential blood-based biomarker for Alzheimer's and other neurodegenerative diseases seems even more promising thanks to new research from a Massachusetts General Hospital-led study.

27 May 2020

Molecular pair offers hope for development of new Parkinson's treatment

A promising molecular pair has offered hope that could lead to the development of a new treatment to slow down Parkinson's disease, a study by Nanyang Technological University, Singapore and Harvard University has found.

27 May 2020

City experts to develop a hybrid sensor for detection of diabetes

Dr Sumsun Naher and Professor Aziz Rahman have received a Marie Curie Fellowship to develop a hybrid sensor for the detection of diabetes from exhaled breath.

27 May 2020

SARS-CoV-2 RNA in blood tests not associated with infectious virus

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has challenged hospitals and laboratory services worldwide. Diagnostic testing for SARS-CoV-2 initially lagged but is now primarily based on the use of reverse transcriptase-polymerase chain reaction (RT-PCR) to detect viral nucleic RNA in the samples. However, viral RNA has also been reported in several small series of cases, though its significance and frequency remain unclear.

27 May 2020

Simple urine-testing method for people with kidney stones offers results in 30 minutes

An improved urine-testing system for people suffering from kidney stones inspired by nature and proposed by researchers from Penn State and Stanford University may enable patients to receive results within 30 minutes instead of the current turnaround time of a week or more.

27 May 2020

ACE2 receptors in the kidney not linked to high BP or RAS blockers

Even as the COVID-19 pandemic continues to smolder and flare up in various parts of the world, researchers are still trying to make sense of the virus, its routes of spread, its target tissues, and the immune responses it induces. One crucial piece of knowledge is that the primary viral receptor is a human enzyme called angiotensin-converting enzyme 2 (ACE2).

27 May 2020

Nimodipine-loaded biodegradable fibers to protect nerve cells after brain surgery

Brain surgery poses a major threat to nerve cells. Even slight injuries can kill the sensitive cells. The drug nimodipine could help prevent this.

27 May 2020

Mouse model mimics clinical course and pathology observed in COVID-19 patients

A mouse model of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reproduces features observed in human patients, researchers report May 26 in the journal Cell Host & Microbe.

27 May 2020

Researchers develop promising immunotherapy treatment for glioblastoma

Researchers of McMaster University and the University of Toronto have developed a promising immunotherapy treatment for a deadly form of adult brain cancer called glioblastoma.

27 May 2020

Ivy Center opens new clinical trial to evaluate experimental drug cocktail for glioblastoma

The Ivy Brain Tumor Center at Barrow Neurological Institute announced that patient recruitment has opened for a new Phase 0 clinical trial to evaluate two targeted therapy drugs, abemaciclib and LY3214996.

27 May 2020

No-deductible preventive drugs can reduce out-of-pocket costs for diabetic patients

For patients with diabetes - especially those with lower incomes - preventive drug lists (PDLs) of essential medications available with no deductible can reduce out-of-pocket costs while increasing use of important treatments, reports a study in a June supplement to Medical Care.

27 May 2020

Researchers are taking inventory of drugs used to treat COVID-19

With doctors and researchers around the world searching for effective treatments for COVID-19, many drugs approved to treat other diseases are being used in hopes that they'll be effective against the virus, a use that's known as "off-label."

27 May 2020

Blood News and Research

Clinical study shows promising results for treatment of VHL disease-associated renal tumors

Type 2 diabetes is more prevalent in American Indians and Alaska Natives

PKU-led team identifies potent neutralizing antibodies against SARS-CoV-2

Antibody tests were hailed as way to end lockdowns. Instead, they cause confusion.

Molecular signatures can predict outcome of sepsis patients based on their immune response

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

Clinical trial of COVID-19 vaccine starts in Australia

WVU partnership produces thousands of swabs to meet demands for COVID-19 testing

Research provides new evidence for potential blood-based biomarker for Alzheimer's

Molecular pair offers hope for development of new Parkinson's treatment

City experts to develop a hybrid sensor for detection of diabetes

SARS-CoV-2 RNA in blood tests not associated with infectious virus

Simple urine-testing method for people with kidney stones offers results in 30 minutes

ACE2 receptors in the kidney not linked to high BP or RAS blockers

Nimodipine-loaded biodegradable fibers to protect nerve cells after brain surgery

Mouse model mimics clinical course and pathology observed in COVID-19 patients

Researchers develop promising immunotherapy treatment for glioblastoma

Ivy Center opens new clinical trial to evaluate experimental drug cocktail for glioblastoma

No-deductible preventive drugs can reduce out-of-pocket costs for diabetic patients

Researchers are taking inventory of drugs used to treat COVID-19

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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