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Researchers discover ‘brake’ that interferes with HIV's development into infectious agent

Viewed with a microscope, the virus faintly resembles a pineapple--the universal symbol of welcome. But HIV, the virus that causes AIDS, is anything but that. It has claimed the lives of more than 35 million people so far.

1 Dec 2017

Researchers identify vulnerability for glioblastoma subtypes

Glioblastoma, the most common and aggressive form of brain cancer, typically fails to respond to treatment or rapidly becomes drug resistant.

1 Dec 2017

Postnova’s AF2000 FFF system used to unlock mystery of neurodegenerative diseases

Postnova Analytics reports that the Department of Molecular Biology & Biotechnology at the University of Sheffield is using their AF2000 Field Flow Fractionation system to investigate the mechanism of amyloid formation, a protein mis-folding process implicated to be the cause of Alzheimer’s and other neurodegenerative diseases.

From Postnova Analytics 1 Dec 2017

Anti-aging protein could be used as target for rejuvenating cells in the immune system

Anti-aging proteins have long been shown to protect against age-related diseases, such as cancer, neurodegeneration, and cardiovascular disease. A study by researchers at the Gladstone Institutes now reveals that one such protein could also be targeted to rejuvenate cells in the immune system.

1 Dec 2017

Genetics may affect how the body responds to a particular diet

We can add one more thing to the list of traits affected by genetics: how our bodies respond to a particular diet.

1 Dec 2017

New targeted treatment could benefit patients with certain pancreatic tumors

Researchers at the University of Cincinnati College of Medicine have shown that a new targeted treatment could benefit patients with certain pancreatic tumors by preventing spread of the cancer and protecting their heart from damage--a direct result of the tumor.

1 Dec 2017

New drugs Erenumab and Fremanezumab show promise for migraine

Migraine headaches affect thousands of Americans and millions worldwide. There are several medications that are being prescribed for migraines and for many these do not work well.

30 Nov 2017

Scientists use computer analysis to complete antibody blueprint

Antibodies defend our bodies against intruders. These molecules consist of proteins with attached sugars. However, the blueprint directing the processing of these sugars on the protein was not well understood until now.

30 Nov 2017

New immunotherapy study shows positive results in chronic migraine sufferers

A new study of fremanezumab, an immunotherapy that counteracts one of the molecules released during migraine, was found successful in reducing the number of days that chronic migraine sufferers experienced headaches.

30 Nov 2017

Researchers create first semi-synthetic organism that can store and use unnatural genetic information

Researchers from The Scripps Research Institute (TSRI) have designed a bacterium that incorporates two unnatural bases, called X and Y, into genes, in addition to the four natural DNA bases − G, C, A and T − that usually code for proteins.

30 Nov 2017

Altering genetic mutation could enhance FluMist vaccine’s protective effect

Researchers at Johns Hopkins Bloomberg School of Public Health have discovered a genetic mutation in the FluMist intranasal flu vaccine that has the potential to be altered to enhance the vaccine's protective effect.

30 Nov 2017

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

Regenerative medicine researchers at UT Southwestern Medical Center developed an improved and simplified gene-editing technique using CRISPR/Cas9 tools to correct a common mutation that causes Duchenne muscular dystrophy.

30 Nov 2017

Blood test could provide low-cost alternative to MRI for monitoring disease activity in MS

A blood test to monitor a nerve protein in the blood of people with multiple sclerosis (MS) may help predict whether disease activity is flaring up, according to a study published in the November 29, 2017, online issue of Neurology Neuroimmunology and Neuroinflammation, an official journal of the American Academy of Neurology.

30 Nov 2017

Researchers unlock genetic processes underlying cancer

For many, breast cancer is more than just a disease – it's personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.

29 Nov 2017

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

Most complex diseases, such as obesity, longevity, and diabetes, are largely influenced by genetic factors. But at the same time, they are also modulated by environmental stimuli, such as diet and physical activity.

29 Nov 2017

Vanillin could prevent or reduce psoriatic skin inflammation

Small amounts of artificial vanilla extract, also known as vanillin, are in a wide range of products, from baked goods to perfumes.

29 Nov 2017

New microscope optimized to perform studies using optogenetic techniques

A newly developed microscope is providing scientists with a greatly enhanced tool to study how neurological disorders such as epilepsy and Alzheimer's disease affect neuron communication.

29 Nov 2017

Specific gene expression patterns could be key to younger looking skin

Some individuals' skin appears more youthful than their chronologic age. Although many people try to achieve this with creams, lotions, injections, and surgeries, new research published in the Journal of the American Academy of Dermatology indicates that increased expression of certain genes may be the key to intrinsically younger looking - and younger behaving - skin.

29 Nov 2017

UT Southwestern researchers take early step toward personalized care for breast cancer

UT Southwestern Medical Center researchers have developed a method to map protein changes that occur in different subtypes of breast cancer cells in response to DNA damage from a new class of chemotherapy drugs.

29 Nov 2017

New pluripotent stem cell technology provides insights into neuropsychiatric disorders

Studying the genetic code allows researchers to know whether some patients with neuropsychiatric disorders either have extra copies of the CHRNA7 gene or are missing copies. However, little was known about the functional consequences of this genetic imbalance in brain cells.

29 Nov 2017

Protein C News and Research

Researchers discover ‘brake’ that interferes with HIV's development into infectious agent

Researchers identify vulnerability for glioblastoma subtypes

Postnova’s AF2000 FFF system used to unlock mystery of neurodegenerative diseases

Anti-aging protein could be used as target for rejuvenating cells in the immune system

Genetics may affect how the body responds to a particular diet

New targeted treatment could benefit patients with certain pancreatic tumors

New drugs Erenumab and Fremanezumab show promise for migraine

Scientists use computer analysis to complete antibody blueprint

New immunotherapy study shows positive results in chronic migraine sufferers

Researchers create first semi-synthetic organism that can store and use unnatural genetic information

Altering genetic mutation could enhance FluMist vaccine’s protective effect

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

Blood test could provide low-cost alternative to MRI for monitoring disease activity in MS

Researchers unlock genetic processes underlying cancer

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

Vanillin could prevent or reduce psoriatic skin inflammation

New microscope optimized to perform studies using optogenetic techniques

Specific gene expression patterns could be key to younger looking skin

UT Southwestern researchers take early step toward personalized care for breast cancer

New pluripotent stem cell technology provides insights into neuropsychiatric disorders

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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